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SLC7A5

  • Official Full Name

    solute carrier family 7 (amino acid transporter light chain, L system), member 5

  • Overview

    L-type amino acid transporter 1 (LAT1), also known as Solute carrier family 7 member 5 (SLC7A5), is a high-affinity neutral transporter of larger amino acids. It facilitates the cellular amino acid uptake in a sodium independent manner and selectively tr
  • Synonyms

    SLC7A5; solute carrier family 7 (amino acid transporter light chain, L system), member 5; large neutral amino acids transporter small subunit 1; CD98; D16S469E; E16; LAT1; MPE16; 4F2 LC; 4F2 light chain; CD98 light chain; integral membrane protein E16; L-;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • 8His
  • MBP,Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC7A5-4893HCL Recombinant Human SLC7A5 Over-ex<x>pression cell lysate HEK293T Myc/DDK
Human SLC7A5-301594H Recombinant Human SLC7A5 protein, GST-tagged E.coli GST Met1-Ile58
Human SLC7A5-4561H Recombinant Human SLC7A5 protein, His-SUMO&Myc-tagged E.coli His-SUMO&Myc 16-50aa
Human SLC7A5-4562H Recombinant Human SLC7A5 protein, His-SUMO&Myc-tagged E.coli His-SUMO&Myc 16-50aa
Human SLC7A5-1256H Recombinant Human SLC7A5 Protein (A2-T507), 8×His-MBP, Flag tagged Insect Cell 8His-MBP,Flag A2-T507
Mouse SLC7A5-15519M Recombinant Mouse SLC7A5 Protein Mammalian Cell His
Mouse SLC7A5-8423M Recombinant Mouse SLC7A5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SLC7A5-8423M-B Recombinant Mouse SLC7A5 Protein Pre-coupled Magnetic Beads HEK293
Rat SLC7A5-5577R Recombinant Rat SLC7A5 Protein Mammalian Cell His
Rat SLC7A5-5236R Recombinant Rat SLC7A5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SLC7A5-5236R-B Recombinant Rat SLC7A5 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SLC7A5-6867Z Recombinant Zebrafish SLC7A5 Mammalian Cell His
Chicken SLC7A5-2292C Recombinant Chicken SLC7A5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SLC7A5 Related Articles

SLC7A5 involved in several pathways and played different roles in them. We selected most pathways SLC7A5 participated on our site, such as Central carbon metabolism in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC7A5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Central carbon metabolism in cancerPGAM1;PIK3CB;PDHB;PDHA2;PTEN;AKT1;SLC1A5;PIK3CG;PGAM2

SLC7A5 has several biochemical functions, for example, L-amino acid transmembrane transporter activity, L-leucine transmembrane transporter activity, L-phenylalanine transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC7A5 itself. We selected most functions SLC7A5 had, and list some proteins which have the same functions with SLC7A5. You can find most of the proteins on our site.

Function Related Protein
L-amino acid transmembrane transporter activitySLC43A1B;SLC38A7;SLC43A1A;Nat3;SLC43A2A;SLC43A2B;SLC7A7;SLC7A14;SLC7A8
L-leucine transmembrane transporter activitySLC7A5;SLC38A7
L-phenylalanine transmembrane transporter activity
L-tryptophan transmembrane transporter activitySLC7A5;SLC36A4
amino acid transmembrane transporter activityPEX3;SLC7A13;SLC6A17;SLC38A4;SLC6A20;SLC6A16B;SLC6A20A;SLC38A2;SLC7A8
antiporter activitySLC9A3.1;CLCN4;SLC9A6B;SLC7A13;CLCN5;SLC7A5;SLC26A3.1;SLC35E3;CLCN4-2

SLC7A5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC7A5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC7A5.

Ikotun, OF; Marquez, BV; et al. Imaging the L-Type Amino Acid Transporter-1 (LAT1) with Zr-89 ImmunoPET. PLOS ONE 8:-(2013).
Galluccio, M; Pingitore, P; et al. Cloning, Large Scale Over-Expression in E-coli and Purification of the Components of the Human LAT 1 (SLC7A5) Amino Acid Transporter. PROTEIN JOURNAL 32:442-448(2013).
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