• Official Full Name
  • ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
  • Background
  • Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29.
  • Synonyms
  • ST8SIA1; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; sialyltransferase 8 (alpha N acetylneuraminate: alpha 2,8 sialytransferase, GD3 synthase) A , SIAT8, SIAT8A; alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; ST8Sia I; gangliosid
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ST8SIA1, His-tagged
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human ST8SIA1
Source (Host):HEK293Species:Human
Product nameRecombinant Human ST8SIA1 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ST8SIA1 Protein
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ST8SIA1
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ST8SIA1
Source (Host):Species:Human
Product nameRecombinant Human ST8SIA1 293 Cell Lysate

ST8SIA1 Related Articles

Miyata, M; Ichihara, M; et al. UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor alpha and interleukin 6. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 445:504-510(2014).
Bobowski, M; Vincent, A; et al. Estradiol Represses the G(D3) Synthase Gene ST8SIA1 Expression in Human Breast Cancer Cells by Preventing NF kappa B Binding to ST8SIA1 Promoter. PLOS ONE 8:-(2013).