tp53bp2
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  • Official Full Name
  • tumor protein p53 binding protein, 2
  • Background
  • This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Synonyms
  • TP53BP2; tumor protein p53 binding protein, 2; BBP; 53BP2; ASPP2; P53BP2; PPP1R13A; apoptosis-stimulating of p53 protein 2; BCL2-binding protein; renal carcinoma antigen NY-REN-51; tumor suppressor p53-binding protein 2; apoptosis-stimulating protein of p53, 2;

TP53BP2 Related Articles

Sebest, P; Brazdova, M; et al. Differential Salt-Induced Dissociation of the p53 Protein Complexes with Circular and Linear Plasmid DNA Substrates Suggest Involvement of a Sliding Mechanism. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 16:3163-3177(2015).
Reuschenbach, M; Dorre, J; et al. A multiplex method for the detection of serum antibodies against in silico-predicted tumor antigens. CANCER IMMUNOLOGY IMMUNOTHERAPY 63:1251-1259(2014).