• Official Full Name
  • UDP glucuronosyltransferase 2 family, polypeptide B17
  • Background
  • This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis.
  • Synonyms
  • UGT2B17; UDP glucuronosyltransferase 2 family, polypeptide B17; UDP glycosyltransferase 2 family, polypeptide B17; UDP-glucuronosyltransferase 2B17; C19 steroid specific UDP glucuronosyltransferase; C19 steroid specific UDPGT; UDB17; UDP glucuronosyltransferase 2B17; UDPGT 2B17; C19-steroid-specific UDPGT; UDP glycosyltransferase 2 family, member B17; UDP-glucuronyltransferase, family 2, beta-17; C19-steroid-specific UDP-glucuronosyltransferase; UDPGT2B17
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat UGT2B17 Protein

UGT2B17 Related Articles

Izukawa, T; Nakajima, M; et al. Quantitative Analysis of UDP-Glucuronosyltransferase (UGT) 1A and UGT2B Expression Levels in Human Livers. DRUG METABOLISM AND DISPOSITION 37:1759-1768(2009).
Chouinard, S; Yueh, MF; et al. Inactivation by UDP-glucuronosyltransferase enzymes: The end of androgen signaling. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 109:247-253(2008).