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Official Full Name adenylate cyclase 6
Background This gene encodes adenylate cyclase 6, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). The expression of this gene is found in normal thyroid and brain tissues, as well as some tumors; and its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants.
Synonyms ADCY6; adenylate cyclase 6; adenylate cyclase type 6; AC6; ACVI; ADCY 6; ADCYB; Adenylate cyclase type VI; ATP pyrophosphate lyase 6; Ca(2+) inhibitable adenylyl cyclase; DKFZp779F075; EC; KIAA0422; adenylyl cyclase 6; ATP pyrophosphate-lyase 6; ca(2+)-inhibitable adenylyl cyclase
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • E.Coli or Yeast
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADCY6-3178H Recombinant Human ADCY6, GST-tagged E.Coli or Yeast GST
    Human ADCY6-330H Recombinant Human ADCY6 Protein, GST-tagged Wheat Germ GST
    Human ADCY6-9409H Recombinant Human ADCY6 protein, GST-tagged E.coli GST
    Human ADCY6-9410H Recombinant Human ADCY6 protein, His-tagged E.coli His
    Mouse Adcy6-6931M Recombinant Mouse Adcy6 protein, His & T7-tagged E.coli His/T7

    adcy6 involved in several pathways and played different roles in them. We selected most pathways adcy6 participated on our site, such as Activation of GABAB receptors, Adenylate cyclase activating pathway, Adenylate cyclase inhibitory pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with adcy6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of GABAB receptors KCNJ10; GNB3A; KCNJ2A; KCNJ6; ADCY3; ADCY8; KCNJ4; KCNJ9; ADCY1; GNGT2B
    Adenylate cyclase activating pathway ADCY9; ADCY1; ADCY7; ADCY3; ADCY8; ADCY6
    Adenylate cyclase inhibitory pathway ADCY3; ADCY1; ADCY6; ADCY8; ADCY9; ADCY7
    Adrenaline,noradrenaline inhibits insulin secretion ADRA2C; GNB5A; GNB3B; GNB3A; GNB5B; ADCY6; ADRA2A; GNB5
    Adrenergic signaling in cardiomyocytes GNA15.1; PRKACBB; PRKACAA; PPP2R5B; PPP2R3C; PPP1CB; ADCY1A; ATP1A4; PPP2R2BB; CACNA1D
    Aldosterone synthesis and secretion Adcy4; GNAQ; CALM4; CAMK4; ADCY9; PRKCB; PRKD3; CYP11B2; PRKACG; CREB5
    Aquaporin-mediated transport AQP1A.2; MIP; AQP9B; ADCY7; GNB5B; ADCY8; AQP10; AQP10B; GNB3A; AQP1A.1
    Bile secretion ATP1B1; ADCY9; AQP9; ABCC3; ATP1A1; CYP7A1; SCARB1; PRKACG; SLC5A1; ABCB1

    adcy6 has several biochemical functions, for example, ATP binding, adenylate cyclase activity, calcium- and calmodulin-responsive adenylate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by adcy6 itself. We selected most functions adcy6 had, and list some proteins which have the same functions with adcy6. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding IGHMBP2; DCAMKL2; HCK; AK7A; DHX35; RFC2; CDC34A; PLK2B; PAK7; PIM2
    adenylate cyclase activity ADCY1A; ADCY8; ADCY7; ADCY2B; ADCY6; ADCY3; ADCY9; GNAS; ADCY1; ADCY1B
    calcium- and calmodulin-responsive adenylate cyclase activity ADCY6; ADCY1; ADCY3; ADCY8
    metal ion binding CAR1; ZSWIM4; HE1A; SFTPBB; ELAC2; ISL2B; NT5C2B; FOXP1; DMRTA2; SMG1
    protein binding OLA1; AKR1A1; MAB21L1; CDX1; TSNAX; CSRP2BP; BIN2; SGCA; ODAM; MEIS1
    protein kinase binding CCNL1A; Fert2; SHC1; MAPT; PDPK1; CACNB3; FBXO7; SKI; RPS19; AP2A1
    scaffold protein binding NLGN4X; CHRNA7; SHANK1; MDM2; KRT5; CIT; NOS1; CASP8; KRT8; PDE4D

    adcy6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with adcy6 here. Most of them are supplied by our site. Hope this information will be useful for your research of adcy6.


    Cunha-Reis, D; Aidil-Carvalho, MD; et al. Endogenous Inhibition of Hippocampal LTD and Depotentiation by Vasoactive Intestinal Peptide VPAC(1) Receptors. HIPPOCAMPUS 24:1353-1363(2014).
    Dirix, V; Mielcarek, N; et al. Human dendritic cell maturation and cytokine secretion upon stimulation with Bordetella pertussis filamentous haemagglutinin. MICROBES AND INFECTION 16:562-570(2014).

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