AP1M2
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Official Full Name
adaptor-related protein complex 1, mu 2 subunit
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Background
This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals. -
Synonyms
AP1M2; adaptor-related protein complex 1, mu 2 subunit; AP-1 complex subunit mu-2; AP1 mu2; HSMU1B; mu2; Adaptor protein complex AP-1 mu-2 subunit; Adaptor protein complex AP1 mu2 subunit; Adaptor related protein complex 1 mu2 subunit; Adaptor-related protein complex 1 mu-2 subunit; AP mu chain family member mu1B; AP-mu chain family member mu1B; AP1 complex subunit mu2; AP1M2_HUMAN; AP47 2; Clathrin assembly protein complex 1 medium chain 2; Golgi adaptor HA1/AP1 adaptin mu-2 subunit; Golgi adaptor HA1/AP1 adaptin mu2 subunit; HA1 47 kDa subunit 2; MU 1B; Mu adaptin 2; Mu-adaptin 2; Mu1B adaptin; Mu1B-adaptin; golgi adaptor AP-1 47 kDa protein; clathrin coat assembly protein AP47 2; clathrin coat associated protein AP47 2; clathrin-associated adaptor medium chain mu2; MU1B; MU-1B; AP1-mu2;
| Species | Cat.# | Product name | Source (Host) | Tag | Price |
|---|---|---|---|---|---|
| Human | AP1M2-648H | Recombinant Human AP1M2 protein, GST-tagged | Wheat Germ | GST |
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| Human | AP1M2-86HCL | Recombinant Human AP1M2 cell lysate | N/A |
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| Human | AP1M2-1097HF | Recombinant Full Length Human AP1M2 Protein, GST-tagged | In Vitro Cell Free System | GST |
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| Human | AP1M2-183H | Recombinant Human AP1M2 Protein, His-tagged | E.coli | N-His |
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| Mouse | AP1M2-1734M | Recombinant Mouse AP1M2 Protein | Mammalian Cell | His |
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| Mouse | AP1M2-597M-B | Recombinant Mouse AP1M2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | AP1M2-597M | Recombinant Mouse AP1M2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Zebrafish | AP1M2-11734Z | Recombinant Zebrafish AP1M2 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- AP1M2 Related Articles
AP1M2 involved in several pathways and played different roles in them. We selected most pathways AP1M2 participated on our site, such as Adaptive Immune System, Clathrin derived vesicle budding, Disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP1M2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | FGF20A;OSCAR;MICA;IGKV1-5;KLB;SIGLEC9;CTSD;AMICA1;CLEC2H |
| Clathrin derived vesicle budding | CLTB;HIP1RB;NECAP1;BLOC1S1;CTSZ;AP1G1;DTNBP1B;FTH1A;YIPF6 |
| Disease | OGN;KPNA4;CCDC59;CCR5;KPNA5;GYG2;ANTXR1;NPM1;CCNC |
| Golgi Associated Vesicle Biogenesis | AP1B1;TFR1B;TGOLN2;TPD52;TPD52L1;CPD;CNO;DTNBP1B;AP1S1 |
| HIV Infection | NMT2;TAF1L;PSIP1;NPM1;CDK9;RCC1;VPS37A;AP1S1;PDCD6IP |
| Host Interactions of HIV factors | AP1G1;RCC1;AP1M2;PPIAL4A;DOCK2;AP1B1;APOBEC3G;PSIP1;AP1S1 |
| Immune System | CTSLL;POLR3G;TRIM45;RNF135;NCR3LG1;PPIAL4A;ASB14;TXNIPA;NA |
| Infectious disease | SYT2;KPNA5;PACS1;CPSF4;AP1M2;PPIAL4A;PDCD6IP;LTF;AP1S1 |
AP1M2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AP1M2 itself. We selected most functions AP1M2 had, and list some proteins which have the same functions with AP1M2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | DNASE1;MLLT1;KCNJ15;NLRP12;TBX5A;CHAMP1;SIRT7;TMPRSS15;ERAP1 |
AP1M2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP1M2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP1M2.
AP2B1; APP; ECSIT; MAST1; pi3p; ERBB3
- Q&As
- Reviews
Q&As (19)
Ask a questionAP1M2 has polymorphism, and the expression of different polymorphisms is associated with some diseases.
Due to the complex structure and precision production process of AP1M2 , its synthesis cost is relatively high.
The recombinant AP1M2 protein is recognized as an aptamer and is involved in the formation and transport of cell intimal vesicles.
The production process of AP1M2 requires strict quality control measures, including monitoring and verification of gene cloning, protein expression, purification and other links.
Recombinant AP1M2 can affect the regulation of the immune system and has been linked to autoimmune diseases.
The abnormal expression of AP1M2 is thought to be related to the occurrence of neurodegenerative diseases.
Recombinant AP1M2 protein is mainly expressed in lymphoid tissue, bone marrow, spleen and stomach.
The AP1M2 is mainly concentrated in the endoplasmic reticulum and Golgi apparatus during the cell life cycle.
AP1M2 is associated with tumors, autoimmune diseases, Alzheimer's disease and other diseases.
The AP1M2 interacts with CD8A, PEX5, VCP, STAM2 and other genes.
Recombinant protein AP1M2 has certain development prospects as a new means of tumor targeted therapy.
Recombinant protein AP1M2 can promote the proliferation of tumor cells, and thus promote the development and spread of tumors.
Recombinant AP1M2 protein is involved in the regulation of tumor-related signaling pathways, such as PI3K/AKT and Wnt/β-catenin signaling pathways.
The gene for the AP1M2 has been shown to be abnormally expressed in some tumors and can be used as a tumor diagnostic marker.
AP1M2 is related to the formation and proliferation of tumor stem cells.
The application of AP1M2 is not limited to the treatment of tumors, but also includes neurodegenerative diseases.
AP1M2 can be used in industrial production after immobilization, but its limitations lie in its specific structure and application field.
The AP1M2 is related to the regulation of the human immune system and may have a certain impact on the immune system.
AP1M2 can be cleared by the human body, but due to its complex molecular structure, there is still a lack of effective elimination methods.
Customer Reviews (3)
Write a reviewAP1M2 preparation cost is low and cost-effective, which is very suitable for our research. -
The strip locations in Western blot results were consistent with expectations, showing good target recognition capability. -
AP1M2 is really impressive, and the results of each experiment are very consistent, which shows that the production process is very careful. -
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