AP1M2

  • Official Full Name

    adaptor-related protein complex 1, mu 2 subunit

  • Overview

    This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals.
  • Synonyms

    AP1M2; adaptor-related protein complex 1, mu 2 subunit; AP-1 complex subunit mu-2; AP1 mu2; HSMU1B; mu2; Adaptor protein complex AP-1 mu-2 subunit; Adaptor protein complex AP1 mu2 subunit; Adaptor related protein complex 1 mu2 subunit; Adaptor-related protein complex 1 mu-2 subunit; AP mu chain family member mu1B; AP-mu chain family member mu1B; AP1 complex subunit mu2; AP1M2_HUMAN; AP47 2; Clathrin assembly protein complex 1 medium chain 2; Golgi adaptor HA1/AP1 adaptin mu-2 subunit; Golgi adaptor HA1/AP1 adaptin mu2 subunit; HA1 47 kDa subunit 2; MU 1B; Mu adaptin 2; Mu-adaptin 2; Mu1B adaptin; Mu1B-adaptin; golgi adaptor AP-1 47 kDa protein; clathrin coat assembly protein AP47 2; clathrin coat associated protein AP47 2; clathrin-associated adaptor medium chain mu2; MU1B; MU-1B; AP1-mu2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human AP1M2-648H Recombinant Human AP1M2 protein, GST-tagged Wheat Germ GST
Human AP1M2-86HCL Recombinant Human AP1M2 cell lysate N/A
Human AP1M2-1097HF Recombinant Full Length Human AP1M2 Protein, GST-tagged In Vitro Cell Free System GST 423 amino acids
Human AP1M2-183H Recombinant Human AP1M2 Protein, His-tagged E.coli N-His Met1-Met207
Mouse AP1M2-1734M Recombinant Mouse AP1M2 Protein Mammalian Cell His
Mouse AP1M2-597M-B Recombinant Mouse AP1M2 Protein Pre-coupled Magnetic Beads HEK293
Mouse AP1M2-597M Recombinant Mouse AP1M2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish AP1M2-11734Z Recombinant Zebrafish AP1M2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

AP1M2 involved in several pathways and played different roles in them. We selected most pathways AP1M2 participated on our site, such as Adaptive Immune System, Clathrin derived vesicle budding, Disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP1M2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemRNF138;LRR1;CTSO;MAP3K8;UBE2F;FGF8B;GRAP2A;Mill2;SIGLEC10
Clathrin derived vesicle buddingTBC1D8B;DNASE2;AP1B1;TPD52L1;PLDN;DNM2;TCEAL4;AP3S1;SNX9A
DiseaseAP1G1;RDBP;TCEA1;TCEB3;ACAN;NUP50;SFTPC;AP2S1;FDX1
Golgi Associated Vesicle BiogenesisAP3S1;SH3D19;AP4B1;FTH1B;SNX9A;CPD;GAK;AP1G1;PICALM
HIV InfectionPSTPIP2;PPIAL4A;RCC1;SSRP1;CHMP4B;CDK9;PDCD6IP;NMT2;AP1G1
Host Interactions of HIV factorsRCC1;AP1G1;AP1M2;PACS1;PPIAL4A;DOCK2;APOBEC3G;AP1S1;AP1B1
Immune SystemLAT2;IFIT2;CHST13;DEFB119;LTF;NCKIPSD;C1rb;TRIM9;ASB9
Infectious diseaseIPO5;CPSF4;PPIAL4A;CHMP4C;VPS37A;ANTXR2;AP1S1;AP1G1;STX1B

AP1M2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AP1M2 itself. We selected most functions AP1M2 had, and list some proteins which have the same functions with AP1M2. You can find most of the proteins on our site.

Function Related Protein
protein bindingMGP;TUBA3C;C1GALT1C1;TDG;RPS14;POC5;CDK18;GPR19;FRS2

AP1M2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP1M2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP1M2.

AP2B1; APP; ECSIT; MAST1; pi3p; ERBB3

Research Area

Related articles

Rohan, S; Tu, JLJ; et al. Gene expression profiling separates chromophobe renal cell carcinoma from oncocytoma and identifies vesicular transport and cell junction proteins as differentially expressed genes. CLINICAL CANCER RESEARCH 12:6937-6945(2006).
  • Q&As
  • Reviews

Q&As (19)

Ask a question
Is there polymorphism in AP1M2 ? 11/13/2022

AP1M2 has polymorphism, and the expression of different polymorphisms is associated with some diseases.

Is the cost of AP1M2 synthesis relatively high? 10/20/2022

Due to the complex structure and precision production process of AP1M2 , its synthesis cost is relatively high.

What is the biological function of AP1M2 ? 10/15/2022

The recombinant AP1M2 protein is recognized as an aptamer and is involved in the formation and transport of cell intimal vesicles.

How to guarantee the quality of AP1M2 in the production process? 08/07/2022

The production process of AP1M2 requires strict quality control measures, including monitoring and verification of gene cloning, protein expression, purification and other links.

What is the association between recombinant AP1M2 and autoimmune diseases? 07/07/2022

Recombinant AP1M2 can affect the regulation of the immune system and has been linked to autoimmune diseases.

Can recombinant AP1M2 promote neurodegenerative diseases? 03/04/2022

The abnormal expression of AP1M2 is thought to be related to the occurrence of neurodegenerative diseases.

What is the expression pattern of AP1M2 ? 02/23/2022

Recombinant AP1M2 protein is mainly expressed in lymphoid tissue, bone marrow, spleen and stomach.

What is the position distribution of AP1M2 in the cell life cycle? 01/26/2022

The AP1M2 is mainly concentrated in the endoplasmic reticulum and Golgi apparatus during the cell life cycle.

Which diseases are associated with recombinant AP1M2? 07/09/2021

AP1M2 is associated with tumors, autoimmune diseases, Alzheimer's disease and other diseases.

Which genes does the AP1M2 interact with? 03/23/2021

The AP1M2 interacts with CD8A, PEX5, VCP, STAM2 and other genes.

Can recombinant AP1M2 be used as a new means of tumor targeted therapy? 02/04/2021

Recombinant protein AP1M2 has certain development prospects as a new means of tumor targeted therapy.

What is the effect of AP1M2 on tumor cell proliferation? 11/10/2020

Recombinant protein AP1M2 can promote the proliferation of tumor cells, and thus promote the development and spread of tumors.

Which signaling pathways are involved in the regulation of recombinant AP1M2? 05/08/2020

Recombinant AP1M2 protein is involved in the regulation of tumor-related signaling pathways, such as PI3K/AKT and Wnt/β-catenin signaling pathways.

Can the gene of AP1M2 be used as a tumor diagnostic marker? 04/25/2020

The gene for the AP1M2 has been shown to be abnormally expressed in some tumors and can be used as a tumor diagnostic marker.

Is recombinant AP1M2 related to tumor stem cells? 01/31/2020

AP1M2 is related to the formation and proliferation of tumor stem cells.

Is the use of recombinant AP1M2 limited to the treatment of tumors? 10/26/2019

The application of AP1M2 is not limited to the treatment of tumors, but also includes neurodegenerative diseases.

Can AP1M2 be used in industrial production after immobilization? 07/24/2019

AP1M2 can be used in industrial production after immobilization, but its limitations lie in its specific structure and application field.

Does AP1M2 affect the human immune system? 05/13/2019

The AP1M2 is related to the regulation of the human immune system and may have a certain impact on the immune system.

Can AP1M2 be cleared by the human body? 02/14/2019

AP1M2 can be cleared by the human body, but due to its complex molecular structure, there is still a lack of effective elimination methods.

Customer Reviews (3)

Write a review
Reviews
02/06/2021

    AP1M2 preparation cost is low and cost-effective, which is very suitable for our research.

    05/06/2020

      The strip locations in Western blot results were consistent with expectations, showing good target recognition capability.

      10/03/2019

        AP1M2 is really impressive, and the results of each experiment are very consistent, which shows that the production process is very careful.

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