AP1S2 involved in several pathways and played different roles in them. We selected most pathways AP1S2 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP1S2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Lysosome |
ARSA; ASAH1B; NAGLU; AP3S2; CTSLA; ACP5; GBA; ABCB9; SORT1B; LITAF |
AP1S2 has several biochemical functions, for example, NF-kappaB binding, calcium ion binding, calcium-dependent phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AP1S2 itself. We selected most functions AP1S2 had, and list some proteins which have the same functions with AP1S2. You can find most of the proteins on our site.
| Function |
Related Protein |
| NF-kappaB binding |
AP1S2; CDK5RAP3; ANXA4; BRMS1; FOXP3; ANKRD42; CDKN2A; HSPA6; HIF1AN; FAF1 |
| calcium ion binding |
PCDH1G30; CD97; PCDH1G29; LPCAT2; STIM2; ITGB1BP2; EFCAB4A; S100A9; DMP1; F9A |
| calcium-dependent phospholipid binding |
ANXA10; ESYT2; ANXA9; ANXA5B; PCLO; SYT1A; DOC2B; ANXA11A; ANXA11; ANXA11B |
| endopeptidase activity |
TMEM59; CD46; CPS1; PSEN1; MME; PSMA6; MMP1A; SENP3B; KLK1B16; AP1S2 |
| phosphatidylserine binding |
MFGE8; AXL; JPH2; OSBPL8; THBS1; GAS6; RPE65; PLCD1; SCIN; ANXA13 |
| protein binding |
DYNAP; KRIT1; CFH; NGLY1; HUWE1; PRL; HYPK; SH3GLB1; MED26; TNNC2 |
| protein homodimerization activity |
UGT1A1; RBM11; PDK2; ID1; TRIM8; ANO2; FZD9; RCHY1; SPPL2B; VPS24 |
| transporter activity |
FABP7A; SYPA; PTGDSB; NUP98; AQP3; PBSN; SLC22A23; ABCA7; SLC25A38B; SLCO2B1 |
AP1S2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP1S2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP1S2.
AP1G1; AP1S1; TNS2; SLC43A3; AP1G1; AP1G2; NUDT3; CLTA; CPS1; GGCX; ABCG1; SEC13; UBE2M; AP2B1; AP1B1; CLINT1; AP1AR; AFTPH
Stratta, P; Merlotti, G; et al. Calcium-sensing-related gene mutations in hypercalcaemic hypocalciuric patients as differential diagnosis from primary hyperparathyroidism: detection of two novel inactivating mutations in an Italian population. NEPHROLOGY DIALYSIS TRANSPLANTATION 29:1902-1909(2014).
Kim, YA; Choi, HJ; et al. Replication of Caucasian loci associated with bone mineral density in Koreans. OSTEOPOROSIS INTERNATIONAL 24:2603-2610(2013).
