AP1S2
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Official Full Name
adaptor-related protein complex 1, sigma 2 subunit
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- Human
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Fc
- Avi
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | AP1S2-650H | Recombinant Human AP1S2 protein, GST-tagged | Wheat Germ | GST |
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| Human | AP1S2-4967H | Recombinant Human Adaptor-Related Protein Complex 1, Sigma 2 Subunit, His-tagged | Human | His |
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| Human | AP1S2-3546H | Recombinant Human AP1S2, His-tagged | E.coli | His |
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| Human | AP1S2-1073HF | Recombinant Full Length Human AP1S2 Protein, GST-tagged | In Vitro Cell Free System | GST | 157 amino acids |
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| Human | AP1S2-0243H | Recombinant Human AP1S2 Protein (Met1-Thr157), N-His-tagged | E.coli | His | Met1-Thr157 |
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| Rhesus Macaque | AP1S2-346R | Recombinant Rhesus monkey AP1S2 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | AP1S2-174R | Recombinant Rhesus Macaque AP1S2 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Rhesus Macaque | AP1S2-174R-B | Recombinant Rhesus Macaque AP1S2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Zebrafish | AP1S2-11602Z | Recombinant Zebrafish AP1S2 | Mammalian Cell | His |
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| Chicken | AP1S2-1408C | Recombinant Chicken AP1S2 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
AP1S2 involved in several pathways and played different roles in them. We selected most pathways AP1S2 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP1S2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysosome | HEXB;CTSLA;ATP6V0CB;PSAPL1;Ctsl;GNSB;CTSM;CTSH;MFSD8 |
AP1S2 has several biochemical functions, for example, NF-kappaB binding, calcium ion binding, calcium-dependent phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AP1S2 itself. We selected most functions AP1S2 had, and list some proteins which have the same functions with AP1S2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NF-kappaB binding | HSPA6;CPNE1;RELA;CDKN2A;NFKBID;DNAJA3;MTDH;HDAC3;EP300 |
| calcium ion binding | PLCB2;CDH11;MAN1B1;PCDH2G1;MATN2;NOTCH2NL;CALR;NOTCH4;SYTL3 |
| calcium-dependent phospholipid binding | SYT1A;PLA2G4A;SYT17;SYT2;SYTL4;C2CD4B;ANXA10;SYT10;SYT11A |
| endopeptidase activity | APH1C;KLK1B3;SENP3B;PSMB8F;PSMB11;MMP9;PSMA2;ACE;PSMB4 |
| phosphatidylserine binding | FCHO2;GAS6;RPE65;JPH2;CD300A;THBS1;ANXA9;GAP43;CPNE1 |
| protein binding | RBM41;GNB1;RAB1A;TBCEL;CISH;ITGB5;CCDC93;RFX4;FBXW8 |
| protein homodimerization activity | PVRL3;CAMK2B;NRBP1;TENM2;SNF8;PON3;PRKG2;AOC3;RAP1GAP |
| transporter activity | RBP5;SLC13A2;SLC13A4;AQP8A.1;SLC22A17;AP3B2;CRABP2B;SLC25A31;SLC13A5A |
AP1S2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP1S2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP1S2.
AP1G1; AP1S1; TNS2; SLC43A3; AP1G1; AP1G2; NUDT3; CLTA; CPS1; GGCX; ABCG1; SEC13; UBE2M; AP2B1; AP1B1; CLINT1; AP1AR; AFTPH
Research Area
Related articles
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewThe catalytic activity of AP1S2 is very strong, and it can play an excellent catalytic role even under extremely harsh conditions, and its stability is amazing.
Ideal for experiments or applications that require a high degree of repeatability.
AP1S2 have a wide range of applications and can be used in a variety of biological experiments.
Q&As (15)
Ask a questionThe present study suggests that the AP1S2 may be involved in the regulation of cellular DNA replication and repair, but the specific mechanism needs to be further explored.
The abnormal expression of AP1S2 may be related to people's longevity, health, obesity and other aspects. But the relevant mechanism needs to be further explored.
The present study suggests that the AP1S2 may affect cell growth and development mainly through mechanisms such as cell proliferation and differentiation, DNA replication and repair. However, the specific signal transduction mechanism needs further study.
The AP1S2 is mainly associated with cancer and cell proliferation-related diseases.
The abnormal expression of AP1S2 in tumor is closely related to proliferation, invasion, metastasis and prognosis. Targeted therapies that target its expression may have a positive impact on tumor treatment.
There is insufficient evidence that the AP1S2 directly affects the health of the skeletal system. However, it is closely related to the regulation of cell growth and differentiation, and may have an impact on the maintenance and repair of the skeletal system.
The abnormal expression of AP1S2 is closely related to tumor invasion, metastasis and prognosis. It may affect the process of tumor metastasis through various mechanisms.
The current study suggests that the AP1S2 may be a potential target for tumor drug development, but the specific development and application need to be further explored.
The current study found that the abnormal expression of AP1S2 may be related to neurodegenerative diseases, but the specific mechanism needs to be further studied.
Current research evidence suggests that AP1S2 plays an important role in apoptosis and programmed death, but the specific regulatory mechanisms need to be further explored.
It has not yet been determined whether recombinant AP1S2 can be used as a marker of tumor prognosis, and relevant studies need to continue.
At present, there is insufficient evidence to show that the AP1S2 directly affects immunity. However, it is closely related to the regulation of cell growth and differentiation, so it may have an impact on the regulation of immunity.
There is insufficient evidence to show that AP1S2 has a direct impact on maternal and fetal health. However, it is closely related to the regulation of cell growth and differentiation, and may have an impact on embryonic development and maternal and child health.
The expression of AP1S2 may be influenced by genetic factors. The study of its gene regulation mechanism is helpful to better understand the regulatory role of AP1S2 and the pathogenesis of related diseases.
Recombinant AP1S2 protein is involved in the regulation of tumor cell proliferation, metastasis and prognosis, and its targeted therapy may inhibit tumor cell growth, invasion and metastasis through multiple mechanisms to improve patient prognosis.
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