AP2B1 Protein

AP2B1

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AP2B1

Official Full Name adaptor-related protein complex 2, beta 1 subunit
Background Subunit of clathrin associated adaptor protein complex 1 that plays a role in protein sorting in the late Golgi/trans Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Adaptor protein complex 1 (AP1) is an heterotetramer composed of two large adaptins (gamma type subunit AP1G1 and beta type subunit AP1B1), a medium adaptin (mu type subunit AP1M1 or AP1M2) and a small adaptin (sigma type subunit AP1S1 or AP1S2 or AP1S3).
Synonyms AP2B1; adaptor-related protein complex 2, beta 1 subunit; AP-2 complex subunit beta; AP105B; beta1-adaptin; beta2-adaptin; beta-1-adaptin; beta-2-adaptin; beta-adaptin 1; AP-1 complex subunit beta-1; adaptor protein complex AP-2 subunit beta; golgi adapto
    • Species :
    • Bovine
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • In Vitro Cell Free System
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • Flag
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    • N-His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AP2B1-652H Recombinant Human AP2B1 protein, GST-tagged Wheat Germ GST
    Rat Ap2b1-3534R Recombinant Rat Ap2b1, His-tagged E.Coli or Yeast His
    Rat AP2B1-700R Recombinant Rat AP2B1 Protein Mammalian Cell His
    Bovine AP2B1-3533B Recombinant Bovine AP2B1, His-tagged E.Coli or Yeast His
    Zebrafish AP2B1-10288Z Recombinant Zebrafish AP2B1 Mammalian Cell His
    Human AP2B1-8815HCL Recombinant Human AP2B1 293 Cell Lysate HEK293 N/A
    Human AP2B1-1014HF Recombinant Full Length Human AP2B1 Protein, GST-tagged In Vitro Cell Free System GST
    Human AP2B1-186H Recombinant Human AP2B1 Protein, His-tagged E.coli N-His
    Human AP2B1-476HFL Recombinant Full Length Human AP2B1 Protein, C-Flag-tagged Mammalian cells Flag
    Human AP2B1-2317H Recombinant Human AP2B1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human AP2B1-6159H Recombinant Human AP2B1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Ap2b1-1653M Recombinant Mouse Ap2b1 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    AP2B1 involved in several pathways and played different roles in them. We selected most pathways AP2B1 participated on our site, such as Adaptive Immune System, Axon guidance, Beta-catenin independent WNT signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP2B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System LAIR2; LILRA3; KIF20A; SH2D1B; EGF; ITPR2; HLA-DQB2; KLRG1; SPSB1; DCTN6
    Axon guidance HRAS; NRG2A; SLIT2; SEMA3E; CSNK2A1; EPHA7; SEMA3G; DNM1; PEA15A; COL4A4
    Beta-catenin independent WNT signaling AP2A1; CLTC; ROR1; PRICKLE1; AP2S1; ROR2; DVL1; AGO3; AP2A2; AGO1
    Developmental Biology CRMP1; NADL1.1; HFE2; DUSP5; NR5A1; DPYSL4; LEFTY1; ACTR2B; GPC1A; CLTC
    Disease PACS1; CTDP1; AP2A2; SUPT4H1; DOCK2; CHMP4C; AMN; CUX1; CCDC167; GCKR
    EGFR downregulation AP2B1; AP2A1; STAM2; AP2M1; SPRY2; SPRY1; AP2S1; AP2A2; PTPRK
    EPH-Ephrin signaling KDR; EFNB3; EPHA2; SDCBP; CFL1; EPHB4B; DNM1; ACTR2B; EFNA3; SHB
    EPH-ephrin mediated repulsion of cells AP2A2; EFNA5; EFNB1; CLTB; AP2S1; EPHA10; EFNA1; EPHA2A; EFNB2; EPHA2

    AP2B1 has several biochemical functions, for example, contributes_to clathrin adaptor activity, clathrin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AP2B1 itself. We selected most functions AP2B1 had, and list some proteins which have the same functions with AP2B1. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to clathrin adaptor activity AP2S1; AP2A1; AP2B1; AP2M1; AP2A2
    clathrin binding SYT11A; SYT15; SYTL1; CCDC167; SYT1B; SYT6; SYT17; SYT9; CLINT1; NCALD
    protein binding GGPS1; BRD7; RTN3; XRCC6; ZBTB8A; KCNA2; PPIH; NGLY1; MTNR1A; CACNG1
    protein complex binding CPS1; MLKL; TG; Cel; SIX2; ERCC6; TAB1; RAP1A; VPS28; PFKP
    protein transporter activity IPO4; PGAP2; RAMP1; AP2S1; KPNA6; AP1S3; ITGB1BP1; TIMM10; XPO5; AP1G1
    signal sequence binding AP2B1; SRP68; AP2M1

    AP2B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP2B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP2B1.

    LDLRAP1; THAP1; AP1M2; Ap2m1; 10411; SLC25A6

    Kim, YA; Choi, HJ; et al. Replication of Caucasian loci associated with bone mineral density in Koreans. OSTEOPOROSIS INTERNATIONAL 24:2603-2610(2013).
    Jones, ML; Murden, SL; et al. Disruption of AP3B1 by a chromosome 5 inversion: a new disease mechanism in Hermansky-Pudlak syndrome type 2. BMC MEDICAL GENETICS 14:-(2013).

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