Recombinant Human AP2B1 Protein, His-tagged

Cat.No. : AP2B1-186H
Product Overview : Recombinant Human AP2B1 Protein (Thr2-Phe266) with N-His tag was expressed in E. coli.
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  • Gene Information
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Description : The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.
Source : E. coli
Species : Human
Tag : N-His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 33.5 kDa
Accurate Molecular Mass: 31 kDa
Protein length : Thr2-Phe266
Purity : > 97%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name : AP2B1 adaptor-related protein complex 2, beta 1 subunit [ Homo sapiens (human) ]
Official Symbol : AP2B1
Synonyms : AP2B1; adaptor-related protein complex 2, beta 1 subunit; ADTB2, CLAPB1; AP-2 complex subunit beta; beta-adaptin; beta-2-adaptin; adaptin, beta 2 (beta); adaptor protein complex AP-2 subunit beta; adapter-related protein complex 2 beta subunit; clathrin assembly protein complex 2 beta large chain; plasma membrane adaptor HA2/AP2 adaptin beta subunit; clathrin-associated/assembly/adaptor protein, large, beta 1; ADTB2; AP105B; CLAPB1; AP2-BETA; DKFZp781K0743
Gene ID : 163
mRNA Refseq : NM_001030006
Protein Refseq : NP_001025177
MIM : 601025
UniProt ID : P63010

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (20)

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What are the structural characteristics of AP2B1 ? 12/02/2022

AP2B1 s belong to the chaperone family and contain several domains, the main one being the C-glycosyltransferase domain.

What is the difference between AP2B1 and other molecular chaperones? 06/05/2022

The main difference between AP2B1 and other molecular chaperones is that AP2B1 participates in different biological processes, and its structure and function are also different.

Can AP2B1 be used in clinical treatment? 04/25/2022

Recombinant AP2B1 protein may be a therapeutic target for some diseases, but further research and experimental validation are needed.

What is the role of AP2B1 in protein complex? 02/20/2022

The AP2B1 exists primarily as a molecular chaperone and part of a signaling pathway in protein complexes.

What factors affect the expression of AP2B1 ? 11/15/2021

The expression of recombinant AP2B1 protein is influenced by genetic and environmental factors, such as certain gene mutations, drugs, etc.

What is the localization of AP2B1 in the cell? 10/23/2021

The AP2B1 is mainly located in the cytoplasm and endoplasmic reticulum.

Is the biological function of recombinant AP2B1 affected by its expression level? 09/04/2021

The biological function of AP2B1 may be influenced by its expression level, but the specific details need to be further studied.

Which diseases are associated with recombinant AP2B1? 08/30/2021

The AP2B1 is associated with a variety of diseases, including cancer, neurodegenerative diseases, and genetic diseases.

What is the role of AP2B1 in tumor cells? 07/05/2021

Recombinant AP2B1 protein may be involved in tumor growth and metastasis in tumor cells, but further experimental verification is needed.

What is the role of AP2B1 in cell proliferation and apoptosis? 06/02/2021

The role of AP2B1 in cell proliferation and apoptosis still needs further research.

What is the biosynthetic pathway of AP2B1 ? 04/11/2021

The biosynthesis of recombinant AP2B1 requires participation in multiple protein synthesis pathways, including translation, transport, shearing, modification, etc.

What is the interaction of AP2B1 with other molecules? 01/05/2021

There are many interactions between AP2B1 and other molecules, such as protein-protein interactions, biochemical reactions, etc.

What is the role of recombinant AP2B1 in genetic diseases? 06/02/2020

Recombinant AP2B1 protein may be involved in a variety of metabolic, signal transduction and other biological processes in genetic diseases, but the specific role needs to be further studied.

What is the regulatory mechanism of AP2B1 ? 02/06/2020

The regulatory mechanism of AP2B1 includes regulation of many signaling pathways and regulatory elements such as transcription factors.

What is the function of AP2B1 ? 10/26/2019

The recombinant AP2B1 protein is a molecular chaperone involved in biological processes such as regulating internal cellular secretion pathways and endoplasmic reticulum function.

Is the structure, function and regulation of recombinant AP2B1 similar to other proteins? 09/15/2019

The structure, function and regulation of AP2B1 are similar to other proteins in some respects, but the specific differences need to be further studied.

In which tissues is recombinant AP2B1 expressed? 07/22/2019

AP2B1 is widely present in various tissues of the human body, including liver, lung, gastrointestinal tract, kidney and so on.

What is the help of AP2B1 in the treatment of neurological diseases? 06/29/2019

The AP2B1 may have certain research and therapeutic value for the treatment of some neurological diseases.

Can AP2B1 be used as a drug? 06/27/2019

AP2B1 may be used as a drug, which has certain application value in tumor therapy, nerve cell protection, genetic therapy and so on.

Is the study of recombinant AP2B1 meaningful for the treatment of diseases? 03/21/2019

The study of AP2B1 will be helpful in understanding the pathogenesis of the disease and developing treatments.

Customer Reviews (3)

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Reviews
09/27/2022

    Convenient storage, whether it is multiple use or long-term storage, its structure and function have always remained stable, providing great convenience for scientific research work.

    02/04/2022

      Green production process of AP2B1 pays attention to harmonious symbiosis with nature, realizes zero pollution in the production process, and has no negative impact on the environment.

      08/19/2019

        The high activity greatly reduces the time and energy required for chemical reactions, and its economic value is immeasurable.

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