APOA5

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APOA5

Official Full Name apolipoprotein A-V
Background Apolipoproteins are proteins that bind lipids (oil-soluble substances such as fat and cholesterol) to form lipoproteins. They transport the lipids through the lymphatic and circulatory systems. The lipid components of lipoproteins are insoluble in water. However, because of their detergent-like (amphipathic) properties, apolipoproteins and other amphipathic molecules (such as phospholipids) can surround the lipids, creating the lipoprotein particle that is itself water-soluble, and can thus be carried through water-based circulation (i.e., blood, lymph). Apolipoproteins also serve as enzyme cofactors, receptor ligands, and lipid transfer carriers that regulate the metabolism of lipoproteins and their uptake in tissues.
Synonyms UNQ411/PRO773; APOAV; RAP3; apo-AV; apolipoprotein A5; regeneration-associated protein 3
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Flag
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human APOA5-103H Recombinant Human APOA5, Flag-tagged HEK293 Flag
    Human APOA5-2476H Recombinant human APOA5, His-tagged E.coli His
    Human APOA5-26876TH Recombinant Human APOA5, Protein A-tagged HEK293 FLAG
    Human APOA5-5395H Recombinant Human APOA5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human APOA5-693H Recombinant Human APOA5 protein, GST-tagged Wheat Germ GST
    Human APOA5-787H Recombinant Human APOA5 Mammalian Cell His
    Human APOA5-8787HCL Recombinant Human APOA5 293 Cell Lysate HEK293 N/A
    Human APOA5-9750H Recombinant Human APOA5, His-tagged E.coli His
    Mouse Apoa5-1662M Recombinant Mouse Apoa5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse APOA5-1783M Recombinant Mouse APOA5 Protein Mammalian Cell His
    Mouse Apoa5-2088M Recombinant Mouse Apoa5 protein, His & GST-tagged E.coli His/GST
    Rat Apoa5-2089R Recombinant Rat Apoa5 protein, His-tagged E.coli His
    Rat APOA5-720R Recombinant Rat APOA5 Protein Mammalian Cell His

    APOA5 involved in several pathways and played different roles in them. We selected most pathways APOA5 participated on our site, such as Chylomicron-mediated lipid transport, Fatty acid, triacylglycerol, and ketone body metabolism, Lipid digestion, mobilization, and transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with APOA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chylomicron-mediated lipid transport APOEA; APOEB; APOC2; APOA4B.1; APOA5; APOA4B.2; APOBB.1; APOA1B; MTP; APOA4A
    Fatty acid, triacylglycerol, and ketone body metabolism DECR1; ACOT11B; ACAD11; MED19; STIL; SLC25A20; MED16; CTGF; TIAM2; ACSF2
    Lipid digestion, mobilization, and transport FABP11B; APOEB; APOF; APOEA; APOBB.1; LPA; FABP12; APOA4B.2; LMF1; APOA4B.1
    Lipoprotein metabolism APOF; Alb; APOA4A; CETP; MTP; APOA4B.1; APOEA; APOA4B.2; APOEB; ABCA1
    Metabolism CERS5; UPP2; DECR1; ACOT11; ATP5H; PDK3B; AS3MT; FA2H; SLC16A1; CYP24A1
    Metabolism of lipids and lipoproteins AKR1C4; SLC27A5; CYP4F11; CPNE7; AGPAT6; SPTLC1; PPM1LA; ESRRA; GPAT2; FIG4
    PPAR signaling pathway SLC27A1A; FABP7; RXRG; AQP7; ACSL3B; FABP5; PDPK1B; ANGPTL4; ACADL; ACSL1A
    PPARA activates gene expression MED23; MED10; GLIPR1; TIAM2; MED22; MED6; MED29; ANKRD1; PLIN2; MED7

    APOA5 has several biochemical functions, for example, cholesterol binding, cholesterol transporter activity, enzyme activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by APOA5 itself. We selected most functions APOA5 had, and list some proteins which have the same functions with APOA5. You can find most of the proteins on our site.

    Function Related Protein
    cholesterol binding APOA1A; APOD; STARD6; APOA4B.2; STAR; APOC3; SOAT1; SCP2; STARD3; APOEA
    cholesterol transporter activity APOB; APOE; APOA5; APOEB; APOA4; ABCA4; ABCA1B; APOEA; ABCA4A; ABCG4B
    enzyme activator activity ALOX5AP; CFLAR; DBNL; SAE1; TRIM23; APOA5; LTC4S; ARL1; SLX4; PSAPL1
    enzyme binding TARBP2; CDC20; KMT2E; PRKCH; SCN5A; PPP1R3B; SRC; KRT79; ARPC4; LDB1
    heparin binding HDGF; RPL22; ADAMTS8; PLA2G2D; NRP1; CXCL13; SERPINC1; PLA2G5; FGF2; APLP2
    lipase activator activity APOA5
    lipase binding APOB; GPIHBP1; LRPAP1; PLIN5; FAF2; APOA5
    lipid binding CRABP1B; O3far1; RBP7B; PSAP; STARD8; FABP5; MAL; HDLBP; MARK2; STARD13
    lipoprotein lipase activator activity APOC2; APOA5; APOH
    lipoprotein particle receptor binding LRP1; APOA5; Reln
    low-density lipoprotein particle receptor binding LANCL1; PCSK9; APOB; APOEA; HSP90B1; CCDC167; MESDC2; LRPAP1; APOA5; LRP2
    phosphatidylcholine binding APOA4; CHMP3; CHMP2A; APOA4B.2; SERPINA5; GPR119; PCTP; GPR12; APOA2; APOA5
    phosphatidylcholine-sterol O-acyltransferase activator activity APOC1; APOE; APOA4B.1; APOA4A; APOEB; APOA2; APOA4B.2; APOA1A; APOA1; APOEA
    phospholipid binding OTC; CPS1; GOT2; NBEA; PREX1; AMPH; F10; APOA1; ESYT1; ANXA5

    APOA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of APOA5.

    LPL; LPL; FAS; RAB5B; SMARCD1; q99ib8-pro_0000045598

    Ashraf, AP; Beukelman, T; et al. Type 1 Hyperlipoproteinemia and Recurrent Acute Pancreatitis due to Lipoprotein Lipase Antibody in a Young Girl with Sjogren's Syndrome. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 96:3302-3307(2011).
    Chen, Q; Reis, SE; et al. Association of anti-oxidized LDL and candidate genes with severity of coronary stenosis in the Women's Ischemia Syndrome Evaluation study. JOURNAL OF LIPID RESEARCH 52:801-807(2011).

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