apoa5

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apoa5

Official Full Name apolipoprotein A-V
Background Apolipoproteins are proteins that bind lipids (oil-soluble substances such as fat and cholesterol) to form lipoproteins. They transport the lipids through the lymphatic and circulatory systems. The lipid components of lipoproteins are insoluble in water. However, because of their detergent-like (amphipathic) properties, apolipoproteins and other amphipathic molecules (such as phospholipids) can surround the lipids, creating the lipoprotein particle that is itself water-soluble, and can thus be carried through water-based circulation (i.e., blood, lymph). Apolipoproteins also serve as enzyme cofactors, receptor ligands, and lipid transfer carriers that regulate the metabolism of lipoproteins and their uptake in tissues.
Synonyms UNQ411/PRO773; APOAV; RAP3; apo-AV; apolipoprotein A5; regeneration-associated protein 3
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Flag
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human APOA5-103H Recombinant Human APOA5, Flag-tagged HEK293 Flag
    Human APOA5-2476H Recombinant human APOA5, His-tagged E.coli His
    Human APOA5-26876TH Recombinant Human APOA5, Protein A-tagged HEK293 FLAG
    Human APOA5-693H Recombinant Human APOA5 protein, GST-tagged Wheat Germ GST
    Human APOA5-787H Recombinant Human APOA5 Mammalian Cell His
    Human APOA5-8787HCL Recombinant Human APOA5 293 Cell Lysate HEK293 N/A
    Human APOA5-9750H Recombinant Human APOA5, His-tagged E.coli His
    Mouse APOA5-1783M Recombinant Mouse APOA5 Protein Mammalian Cell His
    Mouse Apoa5-2088M Recombinant Mouse Apoa5 protein, His & GST-tagged E.coli His/GST
    Rat Apoa5-2089R Recombinant Rat Apoa5 protein, His-tagged E.coli His
    Rat APOA5-720R Recombinant Rat APOA5 Protein Mammalian Cell His

    apoa5 involved in several pathways and played different roles in them. We selected most pathways apoa5 participated on our site, such as Chylomicron-mediated lipid transport, Fatty acid, triacylglycerol, and ketone body metabolism, Lipid digestion, mobilization, and transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with apoa5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chylomicron-mediated lipid transport APOA4A; APOC2; APOBB.1; APOA5; APOEB; APOA4B.2; APOA1B; MTP; APOA4B.1; APOEA
    Fatty acid, triacylglycerol, and ketone body metabolism SLC25A1A; ACOT11; MED29; MED8; ACSF2; DGAT1B; Agmo; ELOVL1A; G0S2; MMAA
    Lipid digestion, mobilization, and transport FABP11A; Alb; APOA4B.2; LMF1; MTP; APOA4B.1; APOEB; LMF2; LPA; CLPS
    Lipoprotein metabolism APOA4B.2; Alb; APOEA; ABCA1; APOEB; APOA4B.1; APOA5; MTP; CETP; APOA1B
    Metabolism MED10; CYP2W1; KCNC2; CYP4F11; HAS3; UGT1B5; ACY3.2; CYP2D6; ALOX5AP; CYP2N13
    Metabolism of lipids and lipoproteins MED16; ARSJ; CYP24A1; MED19; MTP; FABP12; OSBP; CPNE3; PPM1L; ARV1
    PPAR signaling pathway Scd2; AQP7; RXRBA; DBI; HMGCS2; PLTP; MMP1; SCD; APOA1A; PPARG
    PPARA activates gene expression MED9; MED20; MED31; PLIN2; MED22; G0S2; ANKRD1; MTF1; MED18; MED21

    apoa5 has several biochemical functions, for example, cholesterol binding, cholesterol transporter activity, enzyme activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by apoa5 itself. We selected most functions apoa5 had, and list some proteins which have the same functions with apoa5. You can find most of the proteins on our site.

    Function Related Protein
    cholesterol binding CYP11A1; OSBPL8; TSPO; APOA4; PMP2; OSBPL10; NPC1; SOAT1; APOEA; APOF
    cholesterol transporter activity CETP; ABCA1; ABCA4A; APOA4; APOB; ABCG1; ABCA7; APOEA; ABCA4; APOE
    enzyme activator activity GTF3C4; SAE1; PPP1R12B; APOA5; PRKCD; PITRM1; ALOX5AP; HSPB2; CLPS; LTC4S
    enzyme binding ADORA2A; CD4; TRP53; IL6R; HIST1H2AK; RAD9A; RAC1; CYP1A1; CYP1A2; GOT2
    heparin binding CTGF; COL5A1; APOH; ABI3BP; HSD17B12; CXCL11; MPO; PLA2G5; VEGFB; CCL2
    lipase activator activity APOA5
    lipase binding APOB; LRPAP1; GPIHBP1; PLIN5; FAF2; APOA5
    lipid binding FABP1B.1; YBX2; OSBPL11; COQ9; IQSEC1; ACOT12; BAX; C3; FABP6; FFAR1
    lipoprotein lipase activator activity APOH; APOA5; APOC2
    lipoprotein particle receptor binding LRP1; Reln; APOA5
    low-density lipoprotein particle receptor binding APOA5; DKK1; CCDC167; APOEA; SLC9A3R2; SNX17; SYT1; LDLRAP1; PCSK9; LRP2
    phosphatidylcholine binding ALDOB; RASGRP1; APOA1A; APOA1; GPR119; APOA2; APOA5; APOA4B.1; RPE65; APOA4B.2
    phosphatidylcholine-sterol O-acyltransferase activator activity APOA1A; APOE; APOA2; APOEB; APOA4; APOA4B.1; APOA5; APOA4A; APOA1; APOC1
    phospholipid binding NR5A2; DAPP1; NSMAF; NBEA; SPTBN1; SHC1; PLA2G7; PLA2G4C; SEC14L2; NR5A1

    apoa5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with apoa5 here. Most of them are supplied by our site. Hope this information will be useful for your research of apoa5.

    LPL; LPL; FAS; RAB5B; SMARCD1; q99ib8-pro_0000045598

    Ashraf, AP; Beukelman, T; et al. Type 1 Hyperlipoproteinemia and Recurrent Acute Pancreatitis due to Lipoprotein Lipase Antibody in a Young Girl with Sjogren's Syndrome. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 96:3302-3307(2011).
    Chen, Q; Reis, SE; et al. Association of anti-oxidized LDL and candidate genes with severity of coronary stenosis in the Women's Ischemia Syndrome Evaluation study. JOURNAL OF LIPID RESEARCH 52:801-807(2011).

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