ARL5B
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Official Full Name
ADP-ribosylation factor-like 5B
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Overview
ARL5B (ARL8) belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs; see MIM 103180). ARLs and ARFs are part of the RAS superfamily of regulatory GTPases. -
Synonyms
ARL5B; ADP-ribosylation factor-like 5B; ADP ribosylation factor like 8 , ARL8; ADP-ribosylation factor-like protein 5B; ADP-ribosylation factor-like 8; ADP-ribosylation-like factor 8; ADP-ribosylation factor-like protein 8; ARL8;
- Recombinant Proteins
- Cell & Tissue Lysates
- Antibody
- Chicken
- Human
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ARL5B-815H | Recombinant Human ARL5B protein, GST-tagged | Wheat Germ | GST |
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| Human | ARL5B-9860H | Recombinant Human ARL5B, GST-tagged | E.coli | GST | 1-179a.a. | |
| Human | ARL5B-26184TH | Recombinant Human ARL5B, His-tagged | E.coli | His | 299 amino acids |
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| Human | ARL5B-3614H | Recombinant Human ARL5B, His-tagged | E.coli | His |
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| Human | ARL8-822H | Recombinant Human ARL8 protein, GST-tagged | Wheat Germ | GST |
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| Human | ARL5B-8709HCL | Recombinant Human ARL5B 293 Cell Lysate | HEK293 | N/A |
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| Human | ARL5B-1424HF | Recombinant Full Length Human ARL5B Protein, GST-tagged | In Vitro Cell Free System | GST | 179 amino acids |
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| Human | ARL5B-26182TH | Recombinant Human ARL5B | N/A |
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| Chicken | ARL5B-3903C | Recombinant Chicken ARL5B | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
ARL5B involved in several pathways and played different roles in them. We selected most pathways ARL5B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARL5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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ARL5B has several biochemical functions, for example, GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARL5B itself. We selected most functions ARL5B had, and list some proteins which have the same functions with ARL5B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | EIF5B;GLUD2;ANXA6;ARL4CA;MTIF2;DIRAS1A;EEF2A.1;RALB;RAB7A |
ARL5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARL5B here. Most of them are supplied by our site. Hope this information will be useful for your research of ARL5B.
- Q&As
- Reviews
Q&As (7)
Ask a questionWhile the specific protein interactors of ARL5B are not yet fully elucidated, being a member of the ARL family indicates that it likely interacts with other proteins involved in vesicle trafficking and membrane dynamics within the cell.
Yes, ARL5B protein is evolutionarily conserved across different species, including mammals, suggesting its functional significance in various biological processes.
Currently, there is limited information on post-translational modifications of ARL5B protein. Further research is needed to determine if ARL5B undergoes any modifications, such as phosphorylation or prenylation.
Currently, there are no known therapeutic targets or drugs specifically targeting ARL5B. Further understanding of its function and involvement in diseases is needed to explore its therapeutic potential.
The role of ARL5B in human diseases is currently unclear due to limited research. However, dysregulation of similar proteins involved in vesicle trafficking and membrane dynamics has been associated with various disorders, including neurodegenerative diseases and cancer.
To the best of our knowledge, there are no animal models available specifically targeting ARL5B for studying its function or disease associations. More research is required to develop such models in order to investigate its specific roles.
Limited research has been conducted on the regulation of ARL5B expression. However, some studies suggest that ARL5B expression may be regulated in a tissue-specific manner or in response to specific stimuli. Further investigations are needed to fully understand its regulation.
Customer Reviews (8)
Write a reviewthe manufacturer can play a vital role in supporting and optimizing the research process.
Manufacturers can provide researchers with purified and validated ARL5B protein, ensuring its quality and reliability for use in experiments and trials.
This ensures the consistency and reproducibility of experimental results, promoting confidence in the obtained data.
They can assist in identifying the most suitable experimental protocols or provide recommendations for optimal usage.
This can be particularly important in clinical trials to ensure accurate and reliable results.
The manufacturer can offer technical support and expertise to guide researchers through the experimental process.
Manufacturers may offer the option for custom protein production.
manufacturers offer customization options, such as alternative conjugation methods or tailored formulations, allowing researchers to optimize ARL5B protein to their specific experimental needs.
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