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Official Full Name ATPase, Ca++ transporting, plasma membrane 4
Background Plasma membrane calcium-transporting ATPase 4 is an enzyme that in humans is encoded by the ATP2B4 gene.
Synonyms ATP2B4; ATPase, Ca++ transporting, plasma membrane 4; plasma membrane calcium-transporting ATPase 4; AT2B4_HUMAN; ATP2B2; ATPase Ca++ transporting plasma membrane 4; Cation transporting ATPase; DKFZp686G08106; DKFZp686M088; Matrix remodelling associated 1; Matrix remodelling associated protein 1; Matrix-remodeling-associated protein 1; MXRA 1; MXRA1; OTTHUMP00000034088; OTTHUMP00000034089; Plasma membrane calcium ATPase 4; Plasma membrane calcium ATPase isoform 4; Plasma membrane calcium pump isoform 4; Plasma membrane calcium transporting ATPase 4; PMCA 4; PMCA4; PMCA4b; PMCA4x; Sarcolemmal calcium pump; ATPase, Ca++ transporting, plasma membrane 4 ATP synthase, H+ transporting, mitochondrial F1
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ATP2B4-2588H Recombinant Human ATP2B4 protein, His-tagged E.coli His
    Human ATP2B4-301117H Recombinant Human ATP2B4 protein, GST-tagged E.coli GST
    Human ATP2B4-27795TH Recombinant Human ATP2B4 Wheat Germ N/A
    Human ATP2B4-2945H Recombinant Human ATP2B4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ATP2B4-6544H Recombinant Human ATP2B4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ATP2B4-973H Recombinant Human ATP2B4 protein, GST-tagged Wheat Germ GST
    Mouse Atp2b4-1767M Recombinant Mouse Atp2b4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat ATP2B4-864R Recombinant Rat ATP2B4 Protein Mammalian Cell His
    Rat ATP2B4-865R Recombinant Rat ATP2B4 Protein, His-tagged E. coli His
    Rhesus Macaque ATP2B4-451R Recombinant Rhesus monkey ATP2B4 Protein, His-tagged Mammalian Cell His
    Zebrafish ATP2B4-4741Z Recombinant Zebrafish ATP2B4 Mammalian Cell His

    ATP2B4 involved in several pathways and played different roles in them. We selected most pathways ATP2B4 participated on our site, such as Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP2B4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium signaling pathway PLCD3; LHCGR; SPHK2; ATP2A3; CALM3; CACNA1SB; GRIN1; TACR1; SLC8A2; ITPKB
    cGMP-PKG signaling pathway ATP1B2; PIK3R5; MEF2A; INS2; OPRD1; AGTR1B; GNAI1; ATP1A3; PLCB1; VDAC1
    cAMP signaling pathway PLN; PRKACB; GPR119; ACOX1; CREB5; HTR6; LIPE; CREB3L1; GNAS; HHIP
    Adrenergic signaling in cardiomyocytes ATP1A3B; PIK3R1; ATP1A2; CREB3L3; ATF6B; CACNA2D1A; PIK3CB; CACNB2; PPP1R1A; PPP2R5EA
    Salivary secretion MUC7; GNAQ; PRH1; LPO; LYZ1; BEST2; ATP1A4; TRPV6; CALML3; ATP1B2
    Pancreatic secretion RAB11A; Slc4a2; CA2; AMY2A4; ATP2A2; LOC780933; CLCA5; PLA2G2D; Car2; RAP1B

    ATP2B4 has several biochemical functions, for example, ATP binding, PDZ domain binding, calcium-transporting ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP2B4 itself. We selected most functions ATP2B4 had, and list some proteins which have the same functions with ATP2B4. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding UBE2O; DDX10; DYNC1LI2; DTYMK; AK9; FBXO18; RAD50; NEK2; MYO19; ERBB3A
    PDZ domain binding FZD8; GIPC1; CRIPT; SLC9A3R1; DOCK4; ERC1; PSEN1; KIF14; KCNJ4; EXOC4
    calcium-transporting ATPase activity ATP2B2; ATP2B3B; ATP2A1; ATP2C1; ATP2A2B; ATP2B1B; ATP2A2A; ATP2C2; ATP2B1; ATP2B1A
    calmodulin binding IQGAP3; STRN; KCNN2; PDE1C; GAP43; SPTAN1; PLCB3; KCNQ3; CAMK2A; PPP3R1
    metal ion binding TSSK1; MYLIPA; REV1; ITGAX; NUDT12; DMRTA2; NLN; SMYD1A; ZNF554; KLF13
    nitric-oxide synthase binding SLC6A4; DNM2; NOS1AP; CAV1; DMD; CALM2; ACTB; SCN5A; DNM3; CAMK2D
    nitric-oxide synthase inhibitor activity ATP2B4
    contributes_to nitric-oxide synthase inhibitor activity ATP2B4
    protein binding SMR3B; NRL; AKAP7; PRKDC; PYYA; EXOC4; AAK1; COLQ; VASH1; DSN1
    protein phosphatase 2B binding ATP2B4; SOD1; MYOZ2; AKAP1; AKAP5; PPP3CB; SLC9A1; BAD
    scaffold protein binding MAPK3; NLRP1; NLGN3; GRID2; CASP8; P2RY1; SHANK3; ADCY6; SRC; PDE4D
    contributes_to sodium channel regulator activity ATP2B4; SNTA1

    ATP2B4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP2B4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP2B4.

    Nos1; CALCA; STIM1; Nos1; 15-deoxy-delta(12,14; EGFR; 1C; CDK7; YWHAE

    Brandenburger, T; Strehler, EE; et al. Switch of PMCA4 Splice Variants in Bovine Epididymis Results in Altered Isoform Expression during Functional Sperm Maturation. JOURNAL OF BIOLOGICAL CHEMISTRY 286:7938-7946(2011).
    Mangialavori, I; Giraldo, AMV; et al. A New Conformation in Sarcoplasmic Reticulum Calcium Pump and Plasma Membrane Ca2+ Pumps Revealed by a Photoactivatable Phospholipidic Probe. JOURNAL OF BIOLOGICAL CHEMISTRY 284:4823-4828(2009).

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