Recombinant Human ATP2B4 protein, His-tagged
Cat.No. : | ATP2B4-2588H |
Product Overview : | Recombinant Human ATP2B4 protein(281-345 aa), fused to His tag, was expressed in E. coli. |
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Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole. |
Protein length : | 281-345 aa |
AA Sequence : | GIILTLLGVNEDDEGEKKKKGKKQG VPENRNKAKTQDGVALEIQPLNSQE GIDNEEKDKKAVKVP |
Purity : | 95%, by SDS-PAGE with Coomassie Brilliant Blue staining. |
Storage : | Short-term storage: Store at 2-8°C for (1-2 weeks). Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles. |
Reconstitution : | Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage. Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage. |
Gene Name : | ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 [ Homo sapiens ] |
Official Symbol : | ATP2B4 |
Synonyms : | ATP2B4; ATPase, Ca++ transporting, plasma membrane 4; ATP2B2, matrix remodelling associated 1 , MXRA1; plasma membrane calcium-transporting ATPase 4; plasma membrane calcium transporting ATPase 4; PMCA4; sarcolemmal calcium pump; matrix-remodeling-associated protein 1; MXRA1; ATP2B2; PMCA4b; PMCA4x; DKFZp686M088; DKFZp686G08106; |
Gene ID : | 493 |
mRNA Refseq : | NM_001001396 |
Protein Refseq : | NP_001001396 |
MIM : | 108732 |
UniProt ID : | P23634 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionATP2B4 gene mutation may be related to some hereditary diseases such as acoustic neuroma and lung cancer.
This is a calcium transporter, which is mainly responsible for transporting intracellular calcium to the outside of the cell, thereby maintaining the intracellular and extracellular calcium balance.
There are several differences in protein structure and function between ATP2B4 and other atpase B family members, mainly depending on how they are expressed and regulated in different tissues and cells.
The production pathway of ATP2B4 protein mainly includes multiple biological processes such as gene transcription, RNA splicing, protein translation and subsequent modification.
The expression of ATP2B4 may be related to the occurrence and development of diabetes, obesity, cardiovascular disease, liver disease and other diseases.
The relationship between ATP2B4 and cardiovascular disease may be achieved through several mechanisms such as regulating cardiomyocyte contraction and vascular smooth muscle cell contraction.
Customer Reviews (3)
Write a reviewBecause it is not easy to be contaminated, it is stored again.
The protein's activity is truly remarkable, able to catalyze reactions even under extreme conditions.
ATP2B4's stability is truly remarkable, able to maintain its activity even under extreme conditions.
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