Atp2c2

  • Official Full Name

    ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 [ Homo sapiens (human) ]

  • Synonyms

    AT2C2_HUMAN; ATP2C2; ATPase 2C2; ATPase, Ca++ transporting, type 2C, member 2; Calcium-transporting ATPase type 2C member 2; DKFZp686H22230; KIAA0703; Secretory pathway Ca(2+)-ATPase 2; SPCA2;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ATP2C2-10013H Recombinant Human ATP2C2, GST-tagged E.coli GST
Human ATP2C2-1169H Recombinant Human ATP2C2 Mammalian Cell His
Human ATP2C2-269H Recombinant Human ATP2C2 Protein, His-tagged E.coli N-His
Human ATP2C2-2518H Recombinant Human ATP2C2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ATP2C2-2518H-B Recombinant Human ATP2C2 Protein Pre-coupled Magnetic Beads HEK293
Human ATP2C2-0123H Recombinant Human ATP2C2 Protein (Met1-Tyr106), N-GST-tagged E.coli N-GST
Mouse ATP2C2-2126M Recombinant Mouse ATP2C2 Protein Mammalian Cell His
Mouse ATP2C2-857M Recombinant Mouse ATP2C2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse ATP2C2-857M-B Recombinant Mouse ATP2C2 Protein Pre-coupled Magnetic Beads HEK293
Rat ATP2C2-865R Recombinant Rat ATP2C2 Protein Mammalian Cell His
Rat ATP2C2-521R-B Recombinant Rat ATP2C2 Protein Pre-coupled Magnetic Beads HEK293
Rat ATP2C2-521R Recombinant Rat ATP2C2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Atp2c2 Related Articles

Atp2c2 involved in several pathways and played different roles in them. We selected most pathways Atp2c2 participated on our site, such as Ion channel transport, Ion transport by P-type ATPases, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with Atp2c2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ion channel transportCLCN7;ATP1A1A.3;ATP13A;FXYD6;SCNN1D;TRPV3;TTYH2;WWP1;ANO5B
Ion transport by P-type ATPasesATP13A5;ATP1A1A.2;FXYD3;ATP2B3A;CUTC;ATP2C1;ATP1A1A.4;FXYD7;ATP7B
Transmembrane transport of small moleculesUNC79;SLC15A3;TRPC4APA;NHEDC1;LCN9;SLC17A1;SLC31A1;RHCGL1;WNK1

Atp2c2 has several biochemical functions, for example, ATP binding, calcium-transporting ATPase activity, manganese-transporting ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Atp2c2 itself. We selected most functions Atp2c2 had, and list some proteins which have the same functions with Atp2c2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingHELZ2;FYNA;P2RX3A;CAMK2B1;CKMT1A;MAP3K14;HKDC1;PCCB;TRAP1
calcium-transporting ATPase activityATP2B4;ATP2B3B;ATP2A1;ATP2B1A;ATP2B3A;ATP2C1;ATP2B1B;ATP2C2;ATP2B1
manganese-transporting ATPase activityATP2C2;ATP2C1
metal ion bindingPPARAB;DTD1;KEX2;FIZ1;LNX2A;KAT6A;FCER2;GGPS1;AOX3L1
protein bindingC12orf50;SERPINE1;ARL14;CKB;MYO18A;IL10RB;LEMD3;BOK;IL17RA

Atp2c2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Atp2c2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Atp2c2.

ORAI1

Smith, AW; Holden, KR; et al. Deletion of 16q24.1 Supports a Role for the ATP2C2 Gene in Specific Language Impairment. JOURNAL OF CHILD NEUROLOGY 30:517-521(2015).
Wang, GQ; Zhou, YX; et al. Association of specific language impairment candidate genes CMIP and ATP2C2 with developmental dyslexia in Chinese population. JOURNAL OF NEUROLINGUISTICS 33:163-171(2015).
  • Q&As
  • Reviews

Q&As (6)

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What is the link between ATP2C2 and cardiovascular disease? 04/11/2022

ATP2C2 maintains calcium homeostasis in cardiomyocytes, and mutation of ATP2C2 may lead to abnormal myocardial systolic function, which in turn is associated with cardiovascular diseases such as myocardial infarction.

In what physiological processes does ATP2C2 function? 03/01/2022

ATP2C2 plays a role in physiological processes such as intracellular regulation of calcium ion concentration, cytoskeletal assembly, neurotransmitter release, muscle contraction, and cell proliferation.

How do mutations in ATP2C2 cause neurological diseases? 01/12/2022

Mutation of ATP2C2 may lead to the dysfunction of ATP2C2, and then affect the intracellular calcium balance, neurotransmitter release and other key processes in the nervous system, leading to the occurrence of nervous system diseases.

What diseases may be caused by ATP2C22 mutations? 11/17/2021

Mutations in ATP2C2 may be associated with neurological diseases such as Alzheimer's disease, cardiovascular diseases such as myocardial infarction, metabolic disorders, and cancer.

Does ATP2C2 have a potential therapeutic role? 12/19/2019

Given the important role of ATP2C2 in multiple physiological processes, studying its disease-related mutations and calcium regulation mechanism may provide new clues and directions for the treatment of related diseases.

What is the specific role of ATP2C2 in neurotransmitter release? 05/23/2019

This is responsible for the transport and regulation of intracellular calcium ions during neurotransmitter release, ensuring that neurotransmitters can be released correctly into the synaptic cleft.

Customer Reviews (3)

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Reviews
03/24/2020

    Since the protein has a short half-life, it is more potent and less likely to cause side effects compared to other similar proteins.

    09/24/2019

      Protein manufacturers consistently produce products of the highest quality with a firm commitment to purity, potency, and consistency.

      03/24/2019

        ATP2C2 manufacturer's commitment to environmental sustainability is evident in its production processes, using green and renewable resources.

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