• Official Full Name

    ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit

  • Background

    This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the epsilon subunit of the catalytic core. Two pseudogenes of this gene are located on chromosomes 4 and 13. Read-through transcripts that include exons from this gene are expressed from the upstream gene SLMO2.
  • Synonyms

    ATP5E; ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit; ATP synthase subunit epsilon, mitochondrial; F(0)F(1)-ATPase; mitochondrial ATPase; H(+)-transporting two-sector ATPase; mitochondrial ATP synthase epsilon chain; ATPE; MC5DN;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Bovine
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Bovine ATP5E-3718B Recombinant Bovine ATP5E, GST-tagged E.Coli or Yeast GST
    Human ATP5E-10018H Recombinant Human ATP5E, GST-tagged E.coli GST
    Human ATP5E-8602HCL Recombinant Human ATP5E 293 Cell Lysate HEK293 N/A
    Human ATP5E-980H Recombinant Human ATP5E protein, GST-tagged Wheat Germ GST
    Mouse ATP5E-860M Recombinant Mouse ATP5E Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Mouse Atp5e-1769M Recombinant Mouse Atp5e Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse ATP5E-860M-B Recombinant Mouse ATP5E Protein Pre-coupled Magnetic Beads HEK293
    Mouse ATP5E-2133M Recombinant Mouse ATP5E Protein Mammalian Cell His
    Rat ATP5E-526R-B Recombinant Rat ATP5E Protein Pre-coupled Magnetic Beads HEK293
    Rat ATP5E-870R Recombinant Rat ATP5E Protein Mammalian Cell His
    Rat Atp5e-3717R Recombinant Rat Atp5e, GST-tagged E.Coli or Yeast GST
    Rat ATP5E-526R Recombinant Rat ATP5E Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque ATP5E-284R Recombinant Rhesus Macaque ATP5E Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque ATP5E-284R-B Recombinant Rhesus Macaque ATP5E Protein Pre-coupled Magnetic Beads HEK293
    Rhesus Macaque ATP5E-455R Recombinant Rhesus monkey ATP5E Protein, His-tagged Mammalian Cell His
    Zebrafish ATP5E-8514Z Recombinant Zebrafish ATP5E Mammalian Cell His
    • Involved Pathway
    • Protein Function
    • Interacting Protein

    ATP5E involved in several pathways and played different roles in them. We selected most pathways ATP5E participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP5E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Oxidative phosphorylationNDUFB11;NDUFS8B;UQCR11;COX6B2;ATP5H;ATP5G1;ATP6V1BA;ATP6V0E;ATP6V1D
    Parkinsons diseaseCOX6A2;MT-ND4;NDUFS6;PARK2;NDUFA4L2;LRRK2;CASP9;Atp5g2;ATP5H
    Huntingtons diseaseNDUFS1;SLC25A31;Casp3;IFT57;NDUFS5;NDUFA6;PLCB4;POLR2H;PPARGC1A

    ATP5E has several biochemical functions, for example, contributes_to ATPase activity, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP5E itself. We selected most functions ATP5E had, and list some proteins which have the same functions with ATP5E. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to ATPase activityATP5A1;ATP5C1;ABCG8;ABCA7;RUVBL2;ATP6V1H;MSH2;ATP5D;MSH6
    proton-transporting ATP synthase activity, rotational mechanismATP5E;ATP6AP1;ATP6V0C;ATP5B;ATP5A1;ATP6AP1B;ATP5C1;ATP5O
    proton-transporting ATPase activity, rotational mechanismATP6V0E;ATP6V0E1;ATP6V0CB;ATP5C1;ATP5B;ATP6V1AA;ATP6V1C1;ATP5A1;ATP6V0B
    transmembrane transporter activityATP5C1;ATP5E;SLC22A23;SLC2A9L1;RALBP1;ATP5H;SV2C;SLC22A1;ATP5O

    ATP5E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP5E here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP5E.

    CYP17A1; BLK; Atp5a1; SLC36A1; SLC38A2; SLC38A1

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