• Official Full Name

    ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit

  • Overview

    This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the epsilon subunit of the catalytic core. Two pseudogenes of this gene are located on chromosomes 4 and 13. Read-through transcripts that include exons from this gene are expressed from the upstream gene SLMO2.
  • Synonyms

    ATP5E; ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit; ATP synthase subunit epsilon, mitochondrial; F(0)F(1)-ATPase; mitochondrial ATPase; H(+)-transporting two-sector ATPase; mitochondrial ATP synthase epsilon chain; ATPE; MC5DN;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ATP5E-10018H Recombinant Human ATP5E, GST-tagged E.coli GST 1-51a.a.
Human ATP5E-980H Recombinant Human ATP5E protein, GST-tagged Wheat Germ GST
Human ATP5E-8602HCL Recombinant Human ATP5E 293 Cell Lysate HEK293 N/A
Human ATP5E-1392HF Recombinant Full Length Human ATP5E Protein, GST-tagged In Vitro Cell Free System GST 51 amino acids
Mouse ATP5E-2133M Recombinant Mouse ATP5E Protein Mammalian Cell His
Mouse ATP5E-860M Recombinant Mouse ATP5E Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Atp5e-1769M Recombinant Mouse Atp5e Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse ATP5E-860M-B Recombinant Mouse ATP5E Protein Pre-coupled Magnetic Beads HEK293
Rat Atp5e-3717R Recombinant Rat Atp5e, GST-tagged E.Coli or Yeast GST 51
Rat ATP5E-870R Recombinant Rat ATP5E Protein Mammalian Cell His
Rat ATP5E-526R-B Recombinant Rat ATP5E Protein Pre-coupled Magnetic Beads HEK293
Rat ATP5E-526R Recombinant Rat ATP5E Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bovine ATP5E-3718B Recombinant Bovine ATP5E, GST-tagged E.Coli or Yeast GST 51
Rhesus Macaque ATP5E-455R Recombinant Rhesus monkey ATP5E Protein, His-tagged Mammalian Cell His
Rhesus Macaque ATP5E-284R-B Recombinant Rhesus Macaque ATP5E Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ATP5E-284R Recombinant Rhesus Macaque ATP5E Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish ATP5E-8514Z Recombinant Zebrafish ATP5E Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ATP5E involved in several pathways and played different roles in them. We selected most pathways ATP5E participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP5E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Oxidative phosphorylationATP5B;NDUFA11;NDUFA9;COX7A1;UQCRB;ATP6V0A1B;UQCR10;ATP5J2;COX5AA
Parkinsons diseaseSLC6A3;CASP9;SLC25A31;NDUFV3;ATP5G1;COX7A1;COX7B2;ATP5F1;ATP5E
Huntingtons diseaseCOX4I1;SDHA;SP1;NDUFA1;SLC25A31;GNAQ;ATP5G1;GPX1;BAX

ATP5E has several biochemical functions, for example, contributes_to ATPase activity, proton-transporting ATP synthase activity, rotational mechanism, proton-transporting ATPase activity, rotational mechanism. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP5E itself. We selected most functions ATP5E had, and list some proteins which have the same functions with ATP5E. You can find most of the proteins on our site.

Function Related Protein
contributes_to ATPase activityATP5L;ATP5I;RUVBL2;ATP5E;ATP5F1;PPP2R4;ATP5D;ABCA7;RFC3
proton-transporting ATP synthase activity, rotational mechanismATP5B;ATP5A1;ATP5E;ATP5O;ATP6V0C;ATP6AP1B;ATP5C1;ATP6AP1
proton-transporting ATPase activity, rotational mechanismATP6V1E1;ATP6V0E;ATP6V1AA;ATP6V0A2;ATP6AP1;ATP6V1B2;ATP6V0A1B;ATP6V1H;ATP6V0CA
transmembrane transporter activitySV2BA;SLC2A1A;SLC2A13B;SLC22A16;SLC2A9L1;ATP5D;ATP5C1;ATP5H;SV2A

ATP5E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP5E here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP5E.

CYP17A1; BLK; Atp5a1; SLC36A1; SLC38A2; SLC38A1

  • Q&As
  • Reviews

Q&As (6)

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What is the role of ATP5E in tumors? 11/08/2022

ATP5E may play a role in tumor cell metabolism and energy supply.

Are ATP5E mutations associated with nervous system diseases? 06/03/2022

Yes, ATP5E gene mutations are associated with certain neurological disorders such as Parkinson's disease, spinocerebellar ataxia, etc.

What is the role of ATP5E protein in metabolic diseases? 03/28/2022

ATP5E protein may be associated with the occurrence and progression of metabolic diseases such as obesity and diabetes.

How are ATP5E mutations associated with disease? 10/23/2020

Gene mutation may lead to abnormal protein structure or function, which in turn affects the physiological function of the protein and is associated with specific diseases.

What are the regulatory mechanisms of ATP5E? 10/01/2020

ATP5E expression and function are affected by a variety of regulatory mechanisms, including regulation of transcription factors and epigenetic modifications.

In which tissues or organs is ATP5E highly expressed? 01/02/2020

It is highly expressed in multiple tissues and organs, especially metabolically active tissues such as heart, liver, and brain.

Customer Reviews (3)

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    The manufacturer's products are derived from sustainable sources, ensuring minimal impact on the environment and local communities.


      This manufacturer's reputation for excellence in protein production is well deserved, with a focus on customer satisfaction and reliable delivery.


        Because proteins have short half-lives, they can be delivered more precisely and in a controlled manner, ensuring optimal therapeutic effects.

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