ATP6V0D1

  • Official Full Name

    ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1

  • Overview

    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c, c, and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously.
  • Synonyms

    ATP6V0D1; ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1; ATP6D, ATPase, H+ transporting, lysosomal (vacuolar proton pump), member D , ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d isoform 1 , ATPase, H+ transporting, lysosomal 38kDa,;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • MYC
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ATP6V0D1-10037H Recombinant Human ATP, His-tagged E.coli His 1-351a.a.
Human ATP6V0D1-997H Recombinant Human ATP6V0D1 protein, GST-tagged Wheat Germ GST
Human ATP6V0D1-8588HCL Recombinant Human ATP6V0D1 293 Cell Lysate HEK293 N/A
Human ATP6V0D1-1868H Recombinant Human ATP6V0D1 protein, GST-tagged E.coli GST 1-351 aa
Human ATP6V0D1-1091HF Recombinant Full Length Human ATP6V0D1 Protein, GST-tagged In Vitro Cell Free System GST 351 amino acids
Mouse ATP6V0D1-2154M Recombinant Mouse ATP6V0D1 Protein Mammalian Cell His
Mouse ATP6V0D1-871M Recombinant Mouse ATP6V0D1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse ATP6V0D1-871M-B Recombinant Mouse ATP6V0D1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Atp6v0d1-672M Recombinant Mouse Atp6v0d1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Zebrafish ATP6V0D1-10021Z Recombinant Zebrafish ATP6V0D1 Mammalian Cell His
Chicken ATP6V0D1-5584C Recombinant Chicken ATP6V0D1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ATP6V0D1 Related Articles

ATP6V0D1 involved in several pathways and played different roles in them. We selected most pathways ATP6V0D1 participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP6V0D1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Oxidative phosphorylationNDUFB3;ATP6V1G3;ATP6V0A1;NDUFS2;ctaG;COX10;ATP5G3;SDHC;ATP5IA
Metabolic pathwaysPDHA1A;ACLY;OGDHL;PPAP2CB;ALG3;AKR1B10;ZNF408;NME1;COX6B2
LysosomeCTSC;PSAP;NAGA;ARSA;GGA3;GNSA;GUSB;CLN3;SLC11A2
PhagosomeCd209g;FAM49BA;ITGB2L;TUBA3A;DYNC1LI2;MSR1;RAB7B;ATP6V1C1A;TUBB2
Synaptic vesicle cycleSLC17A6;UNC13C;SNAP25;ATP6V0D2;ATP6V1E2;RAB3A;CPLX2;STX3;ATP6V0A1
Collecting duct acid secretionATP6V1A;ATP6V0C;SLC12A7;ATP6V1D;ATP6V1G1;Car2;ATP6V1C1;ATP6V1F;CA2
Vibrio cholerae infectionATP6V0D1;ACTG1;ATP6V0E1;TJP2;PRKACG;PRKACB;PRKCA;MUC2;ATP6V1H
Epithelial cell signaling in Helicobacter pylori infectionF11R;MAP3K14;ATP6V0D2;MAPK13;LYN;RELA;IKBKG;CXCL1;ADAM17
TuberculosisHLA-DMB;H2-AA;ATP6V0D2;MAPK10;ATP6V0B;PLK3;CALM2;Pla2r1;cgr2b
Viral carcinogenesisHLA-C;CREB5;IRF7;GSN;GTF2A1L;CCND1;HIST1H2BB;CASP8;HDAC2
Rheumatoid arthritisATP6V0D2;ATP6V1B2;HLA-DRB4;TNFSF13;ATP6V1D;IL17A;TEK;CTLA4;IL6

ATP6V0D1 has several biochemical functions, for example, hydrogen-exporting ATPase activity, phosphorylative mechanism, protein binding, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP6V0D1 itself. We selected most functions ATP6V0D1 had, and list some proteins which have the same functions with ATP6V0D1. You can find most of the proteins on our site.

Function Related Protein
hydrogen-exporting ATPase activity, phosphorylative mechanismATP6V1G1;ATP6V0D1;ATP6V1E1;ATP6V1E2;ATP6V1G3;ATP6V1C2;ATP6V1C1
protein bindingBCL2;NPM1;CYS1;FAM65B;NHEJ1;LMO2;EPHA10;CD244;PLIN1
protein complex bindingCtsl;EPCAM;TUBB;COG2;NOG;NFKBIA;CALCA;ARRB2;CYFIP1

ATP6V0D1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP6V0D1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP6V0D1.

ATXN1; pi3p; Ccdc9; ATP6AP2; A2M; CDK1; PTPN1; Rab5c; Bmpr1a; TMPO; Vps4b; RAB5C; RAB7A; RAB2A; Cbx1; CLTC; Rmdn3; TMEM63B; Ptpn23; RFWD3

Pacheco-Costa, R; Hassan, I; et al. High Bone Mass in Mice Lacking Cx37 Because of Defective Osteoclast Differentiation. JOURNAL OF BIOLOGICAL CHEMISTRY 289:8508-8520(2014).
Chung, JY; Yi, JW; et al. Changes in Gene Expression in the Rat Hippocampus after Focal Cerebral Ischemia. JOURNAL OF KOREAN NEUROSURGICAL SOCIETY 50:173-178(2011).
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