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Official Full Name bone morphogenetic protein 5
Background This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors.
Synonyms BMP5; bone morphogenetic protein 5; BMP-5; MGC34244
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BMP5-05H Recombinant Human BMP5, Fc tagged Human Cell Fc
    Human BMP5-11H Recombinant Human Bone Morphogenetic Protein 5 E.coli N/A
    Human BMP5-221HG GMP Recombinant Human BMP5 protein, Fc-tagged HEK293 Fc
    Human BMP5-259H Recombinant Human BMP5 Protein, His-tagged E.coli His
    Human BMP5-268H Recombinant Human BMP5 Protein, GST-tagged Wheat Germ GST
    Human BMP5-269H Recombinant Human BMP5 Protein, GST-tagged Wheat Germ GST
    Human BMP5-26H Recombinant Human Bone Morphogenetic Protein 5 NS0 N/A
    Human BMP5-270H Recombinant Human BMP5 Protein, GST-tagged Wheat Germ GST
    Human BMP5-271H Recombinant Human BMP5 Protein, GST-tagged Wheat Germ GST
    Human BMP5-272H Recombinant Human BMP5 Protein, GST-tagged Wheat Germ GST
    Human BMP5-27H Recombinant Human Bone Morphogenetic Protein 5 CHO N/A
    Human BMP5-3074HCL Recombinant Human BMP5 cell lysate Human Cell N/A
    Human BMP5-8317H Recombinant Human BMP5 NS0 N/A
    Mouse Bmp5-260M Recombinant Mouse Bmp5 Protein, His-tagged E.coli His
    Chicken BMP5-6705C Recombinant Chicken BMP5 Mammalian Cell His
    Zebrafish BMP5-11279Z Recombinant Zebrafish BMP5 Mammalian Cell His

    bmp5 involved in several pathways and played different roles in them. We selected most pathways bmp5 participated on our site, such as TGF-beta signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with bmp5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    TGF-beta signaling pathway EP300; ID2B; BMPR1AB; SMAD3A; RHOAA; SMAD9; TGFBR1A; BMPR1BA; CHRD; BMPR1B
    Hippo signaling pathway WNT7B; LLGL2; TGFBR2; CRB2; ITGB2; PPP2CA; YWHAH; SMAD7; GSK3B; TGFB2

    bmp5 has several biochemical functions, for example, BMP receptor binding, cytokine activity, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by bmp5 itself. We selected most functions bmp5 had, and list some proteins which have the same functions with bmp5. You can find most of the proteins on our site.

    Function Related Protein
    BMP receptor binding BMP6; BMP4; BMP5; BMP2B; BMP8A; PYCARD; BMP8B; BMP7A; BMP7; BMP3
    cytokine activity Ccl27a; IL36A; TNFSF14; THPO; TNFSF8; VEGFA; WNT5A; BMP15; IFNT2; IL17D
    growth factor activity GDF6; FBRS; CECR1; FGF1B; PRL2C2; FGF2; TGFA; IGF2B; TGFB2; PSPN
    transforming growth factor beta receptor binding BMP3; GDF10; TGFBR3; GDF6B; GDF9; BMP15; GDF6; MSTN; BMP2; GDF10B

    bmp5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with bmp5 here. Most of them are supplied by our site. Hope this information will be useful for your research of bmp5.

    Endo, Y; Ishiwata-Endo, H; et al. Cloning and characterization of chicken alpha 5 integrin: Endogenous and experimental expression in early chicken embryos. MATRIX BIOLOGY 32:381-386(2013).
    Guan, QN; Li, SY; et al. Reduction of chronic rejection of renal allografts by anti-transforming growth factor-beta antibody therapy in a rat model. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 305:F199-F207(2013).


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