| Description : |
This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors. |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Form : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : |
78.1 kDa |
| AA Sequence : |
MHLTVFLLKGIVGFLWSCWVLVGYA KGGLGDNHVHSSFIYRRLRNHERRE IQREILSILGLPHRPRPFSPGKQAS SAPLFMLDLYNAMTNEENPEESEYS VRASLAEETRGARKGYPASPNGYPR RIQLSRTTPLTTQSPPLASLHDTNF LNDADMVMSFVNLVERDKDFSHQRR HYKEFRFDLTQIPHGEAVTAAEFRI YKDRSNNRFENETIKISIYQIIKEY TNRDADLFLLDTRKAQALDVGWLVF DITVTSNHWVINPQNNLGLQLCAET GDGRSINVKSAGLVGRQGPQSKQPF MVAFFKASEVLLRSVRAANKRKNQN RNKSSSHQDSSRMSSVGDYNTSEQK QACKKHELYVSFRDLGWQDWIIAPE GYAAFYCDGECSFPLNAHMNATNHA IVQTLVHLMFPDHVPKPCCAPTKLN AISVLYFDDSSNVILKKYRNMVVRS CGCH |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
