CHST1
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Official Full Name
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
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Background
This locus encodes a member of the keratin sulfotransferase family of proteins. The encoded enzyme catalyzes the sulfation of the proteoglycan keratin. -
Synonyms
CHST1; carbohydrate (keratan sulfate Gal-6) sulfotransferase 1; carbohydrate sulfotransferase 1; C6ST; KSGal6ST; Carbohydrate chondroitin 6 keratan sulfotransferase1; Carbohydrate chondroitin 6 keratan sulfotransferase; Carbohydrate keratan sulfate Gal 6 sulfotransferase; Carbohydrate keratan sulfate Gal 6 sulfotransferase 1; EC 2.8.2.21; Galactose N acetylglucosamine N acetylglucosamine 6 O sulfotransferase 1; GST 1; Keratan sulfate Gal 6 sulfotransferase; KS6ST; KSST; OTTHUMP00000233116; carbohydrate (chondroitin 6/keratan) sulfotransferase 1; galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1; GST-1;
- Involved Pathway
- Protein Function
- Interacting Protein
CHST1 involved in several pathways and played different roles in them. We selected most pathways CHST1 participated on our site, such as Glycosaminoglycan biosynthesis - keratan sulfate, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycosaminoglycan biosynthesis - keratan sulfate | ST3GAL3;ST3GAL1;B4GALT2;ST3GAL2;B3GNT1;FUT8;B4GALT3;B4GALT1;CHST4 |
CHST1 has several biochemical functions, for example, N-acetylglucosamine 6-O-sulfotransferase activity, keratan sulfotransferase activity, sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST1 itself. We selected most functions CHST1 had, and list some proteins which have the same functions with CHST1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| N-acetylglucosamine 6-O-sulfotransferase activity | Chst5;HS3ST3B1A;CHST4;SULT1ST1;SULT3ST4;HS3ST3B1B;SULT2ST1;HS6ST1B;SULT2ST3 |
| keratan sulfotransferase activity | |
| sulfotransferase activity | CHST2;SULT1ST3;HS3ST1L1;Sult2a2;SULT1ST1;HS3ST3A1;CHST1;SULT1C4;HS3ST3L |
CHST1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHST1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHST1.
SFN; NHP2L1
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