CHST14

Official Full Name

carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
Background

This gene encodes a member of the HNK-1 family of sulfotransferases. The encoded protein transfers sulfate to the C-4 hydroxyl of N-acetylgalactosamine residues in dermatan sulfate. Mutations in this gene have been associated with adducted thumb-clubfoot syndrome.
Synonyms

CHST14; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14; D4ST1, dermatan 4 sulfotransferase 1; carbohydrate sulfotransferase 14; D4ST 1; HD4ST; D4st1; RP23-286G12.2; 2600016L03Rik; ATCS; Carbohydrate (N acetylgalactosamine 4 0) sulfotransferase 14; CHSTE_HUMAN; D4ST-1; Dermatan 4-sulfotransferase 1; hD4ST1; UNQ1925/PRO4400; dermatan 4 sulfotransferase 1; HNK1ST;

Type:
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species :
Human
Mouse
Zebrafish

Source :
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag :
GST
His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	CHST14-100H	Recombinant Human CHST14, His-tagged	HEK293	His	Inquiry
Human	CHST14-1341H	Recombinant Human CHST14 Protein, GST-tagged	Wheat Germ	GST	Inquiry
Human	CHST14-1831HF	Recombinant Full Length Human CHST14 Protein, GST-tagged	In Vitro Cell Free System	GST	Inquiry
Mouse	CHST14-3449M	Recombinant Mouse CHST14 Protein	Mammalian Cell	His	Inquiry
Mouse	CHST14-1673M	Recombinant Mouse CHST14 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	CHST14-1673M-B	Recombinant Mouse CHST14 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	CHST14-12095Z	Recombinant Zebrafish CHST14	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

CHST14 involved in several pathways and played different roles in them. We selected most pathways CHST14 participated on our site, such as Chondroitin sulfate/dermatan sulfate metabolism, Dermatan sulfate biosynthesis, Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Chondroitin sulfate/dermatan sulfate metabolism	CSPG4;B3GAT2;GPC6;CHST14;BCAN;NCAN;BGN;GPC1B;B4GALT7
Dermatan sulfate biosynthesis	BGNB;VCANB;BGNA;DSEL;CHST14;UST;CSPG5B
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	CHST14;CHST3;CHST3A;CHST12A;CHST3B;XYLT1;B3GAT3;XYLT2;CSGALNACT1
Glycosaminoglycan metabolism	B3GAT2;B3GNT1;HS3ST4;SLC35B2;HAS3;BGNB;CSPG5B;OGN;GPC1B
Metabolism	CTH;ETFA;FIG4;CIAO1;DDAH2;COQ7;ACMSD;GNG13A;MED20
Metabolism of carbohydrates	B3GAT2;PFKLB;MAPK1IP1L;SLC26A2;GYG1B;OXSR1;STAB2;SLC26A1;SLC35D2
dermatan sulfate biosynthesis (late stages)

CHST14 has several biochemical functions, for example, N-acetylgalactosamine 4-O-sulfotransferase activity, phosphate ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST14 itself. We selected most functions CHST14 had, and list some proteins which have the same functions with CHST14. You can find most of the proteins on our site.

Function	Related Protein
N-acetylgalactosamine 4-O-sulfotransferase activity	HS3ST1L1;SULT3ST2;SULT1ST2;CHST9;SULT3ST3;SULT2ST3;SULT1D1;SULT1ST3;HS6ST3B
phosphate ion binding	CHST14;RPH3A;GNG12;MTHFD2;PNP;ADSSL1;RELA;OTC;ADSS

CHST14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHST14 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHST14.