CHST14

  • Official Full Name

    carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14

  • Overview

    This gene encodes a member of the HNK-1 family of sulfotransferases. The encoded protein transfers sulfate to the C-4 hydroxyl of N-acetylgalactosamine residues in dermatan sulfate. Mutations in this gene have been associated with adducted thumb-clubfoot syndrome.
  • Synonyms

    CHST14; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14; D4ST1, dermatan 4 sulfotransferase 1; carbohydrate sulfotransferase 14; D4ST 1; HD4ST; D4st1; RP23-286G12.2; 2600016L03Rik; ATCS; Carbohydrate (N acetylgalactosamine 4 0) sulfotransferase 14; CHSTE_HUMAN; D4ST-1; Dermatan 4-sulfotransferase 1; hD4ST1; UNQ1925/PRO4400; dermatan 4 sulfotransferase 1; HNK1ST;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CHST14-100H Recombinant Human CHST14, His-tagged HEK293 His
Human CHST14-1341H Recombinant Human CHST14 Protein, GST-tagged Wheat Germ GST
Human CHST14-1831HF Recombinant Full Length Human CHST14 Protein, GST-tagged In Vitro Cell Free System GST 376 amino acids
Mouse CHST14-3449M Recombinant Mouse CHST14 Protein Mammalian Cell His
Mouse CHST14-1673M Recombinant Mouse CHST14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CHST14-1673M-B Recombinant Mouse CHST14 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CHST14-12095Z Recombinant Zebrafish CHST14 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CHST14 involved in several pathways and played different roles in them. We selected most pathways CHST14 participated on our site, such as Chondroitin sulfate/dermatan sulfate metabolism, Dermatan sulfate biosynthesis, Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chondroitin sulfate/dermatan sulfate metabolismBGN;B4GALT7;NCAN;BGNB;AGRN;GPC1B;CSPG4;GPC6;DSEL
Dermatan sulfate biosynthesisBGNB;UST;DSEL;CHST14;VCANB;CSPG5B;BGNA
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateCHST7;XYLT2;XYLT1;CHST3A;B3GAT3;CHST3B;CHPF2;CHSY1;DSE
Glycosaminoglycan metabolismB4GALT7;SLC35B3;LYVE1;HS3ST4;Gpc2;GLB1L;GPC5A;SLC26A1;KIAA1199
MetabolismADSL;SLC25A15A;SULT1ST6;NDUFAF7;AWAT1;DIO2;TPTE;AZIN1;CYGB2
Metabolism of carbohydratesCHP;NHLRC1;B3GNT3;PFKLB;GLB1L;SLC26A2;SLC5A9;SLC25A1;ST3GAL3A
dermatan sulfate biosynthesis (late stages)

CHST14 has several biochemical functions, for example, N-acetylgalactosamine 4-O-sulfotransferase activity, phosphate ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST14 itself. We selected most functions CHST14 had, and list some proteins which have the same functions with CHST14. You can find most of the proteins on our site.

Function Related Protein
N-acetylgalactosamine 4-O-sulfotransferase activityHS3ST3L;CHST2;CHST3A;SULT1ST1;SULT6B1;SULT1ST4;Sult3a1;SULT1ST8;CHST11
phosphate ion bindingGNG12;G6PC;CHST14;PNP;OTC;RPH3A;SLC34A2;SH2B3;RELA

CHST14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHST14 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHST14.

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