• Official Full Name
  • collagen, type VII, alpha 1
  • Background
  • This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.
  • Synonyms
  • COL7A1; collagen, type VII, alpha 1; EBD1, EBDCT, EBR1, epidermolysis bullosa, dystrophic, dominant and recessive; collagen alpha-1(VII) chain; collagen VII; alpha 1 polypeptide; LC collagen; long-chain collagen; collagen VII, alpha-1 polypeptide; EBD1
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human COL7A1 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse COL7A1 Protein

COL7A1 Related Articles

Tampoia, M; Bonamonte, D; et al. Prevalence of specific anti-skin autoantibodies in a cohort of patients with inherited epidermolysis bullosa. ORPHANET JOURNAL OF RARE DISEASES 8:-(2013).
Has, C; et al. Molecular genetic assays for inherited epidermolysis bullosa. CLINICS IN DERMATOLOGY 29:420-426(2011).