Recombinant Human COL7A1 Protein, Myc/DDK-tagged

• Cat.No.: COL7A1-341H
• Product Overview: Purified recombinant protein of Human collagen, type VII, alpha 1 (COL7A1), full length, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.
• Source: HEK293T
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 295.22 kDa
• Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: > 50 μg/mL as determined by microplate Bradford method
• Storage Buffer: 25 mM Tris-HCl, 100 mM glycine, 10 % glycerol, pH7.3

Gene Information

• Gene Name: COL7A1 collagen type VII alpha 1 chain [ Homo sapiens (human) ]
• Official Symbol: COL7A1
• Synonyms: COL7A1; collagen type VII alpha 1 chain; EBD1; EBR1; EBDCT; NDNC8; collagen alpha-1(VII) chain; LC collagen; collagen VII, alpha-1 polypeptide; collagen, type VII, alpha 1; long-chain collagen
• Gene ID: 1294
• mRNA Refseq: NM_000094
• Protein Refseq: NP_000085
• MIM: 120120
• UniProt ID: Q02388