CXCR7

  • Official Full Name

    chemokine (C-X-C motif) receptor 7

  • Overview

    CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large protein family of G protein-coupled receptors (GPCR). CXCR7 binds with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, which regulates the trafficking
  • Synonyms

    CXCR7; chemokine (C-X-C motif) receptor 7; chemokine orphan receptor 1 , CMKOR1; C-X-C chemokine receptor type 7; GPR159; RDC1; G protein-coupled receptor; chemokine orphan receptor 1; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolo;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Chicken
  • Human
  • Rat
  • Rhesus Macaque
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CXCR7-25H Recombinant Human CXCR7 protein, GST-tagged Wheat Germ GST
Human CXCR7-7159HCL Recombinant Human CXCR7 293 Cell Lysate HEK293 N/A
Human CXCR7-617HF Recombinant Full Length Human CXCR7 Protein, GST-tagged In Vitro Cell Free System GST 362 amino acids
Rat CXCR7-1696R Recombinant Rat CXCR7 Protein Mammalian Cell His
Rat CXCR7-1355R Recombinant Rat CXCR7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CXCR7-1355R-B Recombinant Rat CXCR7 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CXCR7-1117R Recombinant Rhesus monkey CXCR7 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CXCR7-942R Recombinant Rhesus Macaque CXCR7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CXCR7-942R-B Recombinant Rhesus Macaque CXCR7 Protein Pre-coupled Magnetic Beads HEK293
Chicken CXCR7-3678C Recombinant Chicken CXCR7 Mammalian Cell His
Kit-0907 CYP3A4 Green Screening Kit N/A
Kit-1206 CXCR7 CHO-K1 β-Arrestin GPCR Assay Kit N/A
Kit-1207 CXCR7 Activated GPCR Internalization Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CXCR7 involved in several pathways and played different roles in them. We selected most pathways CXCR7 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CXCR7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionRNF207B;CXCR4;BMPR1B;TNFSF12;CCL16;IFNA10;OSM;TNFSF8;PDGFAA

CXCR7 has several biochemical functions, for example, C-X-C chemokine binding, C-X-C chemokine receptor activity, coreceptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CXCR7 itself. We selected most functions CXCR7 had, and list some proteins which have the same functions with CXCR7. You can find most of the proteins on our site.

Function Related Protein
C-X-C chemokine bindingHMGB1;CXCR6;CXCR3;CXCR7
C-X-C chemokine receptor activityCXCR4;CXCR6;CXCR3.1;CCR9A;CXCR4B;CXCR5;CCBP2;CXCR3;CXCR7
coreceptor activityCD8B;RGMB;CD4;PVRL2;CD8A;TMIGD2;ZP2;LY96;HFE2
protein bindingC2orf62;TMEM59;PI4KB;BCKDHA;SPAST;Ccl27a;DIS3L2;BMPR1A;TFRC
scavenger receptor activityPRG4;C8orf84;PRG4B;CXCL16;SCARA3;HHIPL1;GM106;TMPRSS2;LGALS3BP

CXCR7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXCR7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXCR7.

PECAM1; GRB2; nirB; alaS; ATP13A2; MRPL4; ATP5H; ATP5B; ATP5A1; GJB2; ATP5O; CD164; ESPL1; HECTD2; UBR7

Research Area

Related articles

Shi, JY; Yang, LX; et al. CC chemokine receptor-like 1 functions as a tumour suppressor by impairing CCR7-related chemotaxis in hepatocellular carcinoma. JOURNAL OF PATHOLOGY 235:546-558(2015).
Zhang, SS; Lv, C; et al. Corticosterone Mediates the Inhibitory Effect of Restraint Stress on the Migration of Mesenchymal Stem Cell to Carbon Tetrachloride-Induced Fibrotic Liver by Downregulating CXCR4/7 Expression. STEM CELLS AND DEVELOPMENT 24:587-596(2015).
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