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Official Full Name chemokine (C-X-C motif) receptor 7
Background CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large protein family of G protein-coupled receptors (GPCR). CXCR7 binds with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, which regulates the trafficking
Synonyms CXCR7; chemokine (C-X-C motif) receptor 7; chemokine orphan receptor 1 , CMKOR1; C-X-C chemokine receptor type 7; GPR159; RDC1; G protein-coupled receptor; chemokine orphan receptor 1; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolo
    • Species :
    • Chicken
    • Human
    • Rat
    • Rhesus Macaque
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CXCR7-25H Recombinant Human CXCR7 protein, GST-tagged Wheat Germ GST
    Human CXCR7-7159HCL Recombinant Human CXCR7 293 Cell Lysate HEK293 N/A
    Rat CXCR7-1696R Recombinant Rat CXCR7 Protein Mammalian Cell His
    Rhesus Macaque CXCR7-1117R Recombinant Rhesus monkey CXCR7 Protein, His-tagged Mammalian Cell His
    Chicken CXCR7-3678C Recombinant Chicken CXCR7 Mammalian Cell His
    Kit-0907 CYP3A4 Green Screening Kit N/A
    Kit-1206 CXCR7 CHO-K1 β-Arrestin GPCR Assay Kit N/A
    Kit-1207 CXCR7 Activated GPCR Internalization Assay Kit N/A

    cxcr7 involved in several pathways and played different roles in them. We selected most pathways cxcr7 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with cxcr7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction Il6ra; IL6R; FAS; CCR7; IL17RA; IL3; NT5C3; CCR1L1; IFNA1; TNFRSF19

    cxcr7 has several biochemical functions, for example, C-X-C chemokine binding, C-X-C chemokine receptor activity, coreceptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cxcr7 itself. We selected most functions cxcr7 had, and list some proteins which have the same functions with cxcr7. You can find most of the proteins on our site.

    Function Related Protein
    C-X-C chemokine binding CXCR7; CXCR3; CXCR6; HMGB1
    C-X-C chemokine receptor activity CXCR5; CXCR4B; CCR9A; CXCR6; CXCR4; CCBP2; CXCR2; CXCR7; CXCR3; CXCR4A
    coreceptor activity CCR5; CCR8; ACVR2A; CD4; ZP2; CD8B; CXCR6; IGSF1; LRP5; CXCR7
    protein binding C3orf52; DHX58; KRT6C; SLN; PCMT1; GRK6; TDRD1; TRIAP1; TBC1D17; GFM1
    scavenger receptor activity LOXL2; PGBD1; TMPRSS5; CCBP2; CD163; GM106; SCART1; CFI; MSR1; LGALS3BPB

    cxcr7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cxcr7 here. Most of them are supplied by our site. Hope this information will be useful for your research of cxcr7.

    PECAM1; GRB2; nirB; alaS; ATP13A2; MRPL4; ATP5H; ATP5B; ATP5A1; GJB2; ATP5O; CD164; ESPL1; HECTD2; UBR7

    Shi, JY; Yang, LX; et al. CC chemokine receptor-like 1 functions as a tumour suppressor by impairing CCR7-related chemotaxis in hepatocellular carcinoma. JOURNAL OF PATHOLOGY 235:546-558(2015).
    Zhang, SS; Lv, C; et al. Corticosterone Mediates the Inhibitory Effect of Restraint Stress on the Migration of Mesenchymal Stem Cell to Carbon Tetrachloride-Induced Fibrotic Liver by Downregulating CXCR4/7 Expression. STEM CELLS AND DEVELOPMENT 24:587-596(2015).

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