• Official Full Name
  • drebrin-like
  • Background
  • Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.
  • Synonyms
  • DBNL; drebrin-like; ABP1; HIP55; SH3P7; HIP-55; drebrin-like protein; drebrin-F; cervical SH3P7; SH3 domain-containing protein 7; cervical mucin-associated protein; HPK1-interacting protein of 55 kDa; src homology 3 domain-containing protein HIP-55;
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DBNL Protein, GST-tagged
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human DBNL Protein,DDK-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DBNL, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DBNL Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DBNL Protein
Source (Host):Species:Human
Product nameRecombinant Human DBNL 293 Cell Lysate

DBNL Related Articles

Li, ZJ; Park, HR; et al. Pro-oncogenic function of HIP-55/Drebrin-like (DBNL) through Ser269/Thr291-phospho-sensor motifs. ONCOTARGET 5:3197-3209(2014).
Liu, N; Xing, R; et al. HIP-55/DBNL-dependent regulation of adrenergic receptor mediates the ERK1/2 proliferative pathway. MOLECULAR BIOSYSTEMS 10:1932-1939(2014).