|Official Full Name||hyperpolarization activated cyclic nucleotide-gated potassium channel 4|
|Background||The human HCN4 gene encodes the pore-forming subunit of a hyperpolarization-activated cation channel. HCN4 channels contribute to pacemaker currents in the heart and brain.|
|Synonyms||HCN4; hyperpolarization activated cyclic nucleotide-gated potassium channel 4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; hyperpolarization activated cyclic nucleotide-gated cation channel 4; SSS2|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
hcn4 involved in several pathways and played different roles in them. We selected most pathways hcn4 participated on our site, such as HCN channels, Neuronal System, Potassium Channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with hcn4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Neuronal System||SNAP25B; KCNJ1A.5; ARL6IP5B; ARL6IP5A; KCNG4A; GRIP1; CAMKK1B; RAB3AB; KCNC3A; LIN7A|
|Potassium Channels||KCNC3A; KCNV1; KCNK13B; KCNK6; KCNJ1A.3; KCNH1; KCND1; HCN4; ABCC9; KCNK7|
|cAMP signaling pathway||MC2R; FSHR; HTR1B; CALM4; CNGA1; TSHR; CNGA3; NPY; RAC3; PPARA|
hcn4 has several biochemical functions, for example, cAMP binding, identical protein binding, intracellular cAMP activated cation channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by hcn4 itself. We selected most functions hcn4 had, and list some proteins which have the same functions with hcn4. You can find most of the proteins on our site.
|cAMP binding||RAPGEF4; PDE4A; CNGA4; RAPGEF3; HCN4; PDE4D; PDE4B; PRKAR2B; CNGA2; CNMPD1|
|identical protein binding||KCTD13; DAPK3; CBX3; L3MBTL1; MBIP; PFKFB1; SNX8; AGER; DPY30; HTT|
|intracellular cAMP activated cation channel activity||HCN4; CNGA3; CNGA4; CNGA1; CNGA5; HCN2|
|voltage-gated potassium channel activity||KCNJ11; CNGA2; KCNK5; KCNC3A; KCNAB1; KCNH1A; KCNA6; KCNV2; KCNH5A; KCNH2A|
|voltage-gated sodium channel activity||SCN1LAB; SCN1A; HCN2; HCN4; SCN4AA; SCN5A; SCN1B; SCN3A; SCN12AA; SCN8AB|
hcn4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hcn4 here. Most of them are supplied by our site. Hope this information will be useful for your research of hcn4.