Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

HCN4

  • Official Full Name

    hyperpolarization activated cyclic nucleotide-gated potassium channel 4

  • Overview

    The human HCN4 gene encodes the pore-forming subunit of a hyperpolarization-activated cation channel. HCN4 channels contribute to pacemaker currents in the heart and brain.
  • Synonyms

    HCN4; hyperpolarization activated cyclic nucleotide-gated potassium channel 4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; hyperpolarization activated cyclic nucleotide-gated cation channel 4; SSS2;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Flag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HCN4-4630H Recombinant Human HCN4 Protein, GST-tagged Wheat Germ GST
Human HCN4-3477H Recombinant Human HCN4 protein, His-tagged E.coli His 1-213 aa
Human HCN4-1183HFL Recombinant Human HCN4 protein, His&Flag-tagged HEK293 His&Flag 1-1203 aa
Rat HCN4-2809R Recombinant Rat HCN4 Protein Mammalian Cell His
Rat HCN4-2464R-B Recombinant Rat HCN4 Protein Pre-coupled Magnetic Beads HEK293
Rat HCN4-2464R Recombinant Rat HCN4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HCN4 Related Articles
  • HCN4 Related Research Area

HCN4 involved in several pathways and played different roles in them. We selected most pathways HCN4 participated on our site, such as HCN channels, Neuronal System, Potassium Channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with HCN4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
HCN channels
Neuronal SystemKCNV1;KCNH2A;KCNA2;KCNN3;KCNK3A;BCHE;ARL6IP5B;CHRNB2;KCNAB2B
Potassium ChannelsKCNJ14;KCNK7;HCN4;KCNQ2A;KCNH2A;KCNA1;KCNN1A;KCND3;KCNJ1A.1
cAMP signaling pathwayVAV3;LOC100328615;MC2R;PLD1;NPY1R;PPP1CC;SOX9;NPY;PLD2

HCN4 has several biochemical functions, for example, cAMP binding, identical protein binding, intracellular cAMP activated cation channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HCN4 itself. We selected most functions HCN4 had, and list some proteins which have the same functions with HCN4. You can find most of the proteins on our site.

Function Related Protein
cAMP bindingRAPGEF4;CNGA4;PDE2A;PRKAR1B;BVES;PRKAR2B;PDE3A;CNGA2;PRKAR1A
identical protein bindingREG3B;APP;BNIP3L;MRAP2;CEACAM5;COL18A1;DYRK1A;KCNIP2;LRRK1
intracellular cAMP activated cation channel activityCNGA4;HCN2;CNGA1;HCN4;CNGA5;CNGA3
voltage-gated potassium channel activityKCNF1A;KCNK5;KCNC1;KCNA2;KCNS3A;KCNH5A;KCNH6;KCNQ1;KCNA4
voltage-gated sodium channel activitySCN3B;SCN4A;SCN11A;SCN8A;SCN8AA;ASIC4A;SCN1A;SCN5A;SCN2A

HCN4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HCN4 here. Most of them are supplied by our site. Hope this information will be useful for your research of HCN4.

Pauza, DH; Rysevaite, K; et al. Innervation of sinoatrial nodal cardiomyocytes in mouse. A combined approach using immunofluorescent and electron microscopy. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 75:188-197(2014).
Newton, CM; Stoyek, MR; et al. Regional Innervation of the Heart in the Goldfish, Carassius auratus: A Confocal Microscopy Study. JOURNAL OF COMPARATIVE NEUROLOGY 522:456-478(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All HCN4 Products

Required fields are marked with *

My Review for All HCN4 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends