KRT19

  • Official Full Name

    keratin 19

  • Overview

    Cytokeratin 19 is a type I acidic subfamily of intermediate filament protein that is expressed in stratified and simple type epithelia. Keratin 19 is not expressed in hepatocytes; therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumors. Keratin 19 is often co-expressed with keratin 7.
  • Synonyms

    KRT19; keratin 19; K19; CK19; K1CS; keratin, type I cytoskeletal 19; CK-19; keratin-19; cytokeratin 19; cytokeratin-19; keratin, type I, 40-kd; 40-kDa keratin intermediate filament;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Others
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E. coli
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293T
  • Human
  • Human breast adenocarcinoma cell line
  • Human epithelial ovarian cancer cell culture supernatant
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Myc
  • DDK
  • Flag
  • GST
  • His (Fc)
  • Avi
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KRT19-7239H Recombinant Human KRT19 Protein, His tagged E.coli N-His
Human KRT19-616H Recombinant Human Keratin 19 E.coli N/A
Human KRT19-020H Recombinant Human KRT19, DDK-tagged Insect Cell DDK
Human KRT19-019H Recombinant Human KRT19, MYC/DDK-tagged HEK293 Myc/DDK
Human KRT19-175H Recombinant human KRT19 E.coli N/A
Human KRT19-4875HCL Recombinant Human KRT19 293 Cell Lysate HEK293 N/A
Human KRT19-40H Native Human KRT19 protein Human breast adenocarcinoma cell line N/A
Human KRT19-3263H Recombinant Human KRT19 protein, His-tagged HEK293 His
Human KRT19-4865H Recombinant Human KRT19 Protein, GST-tagged Wheat Germ GST
Human KRT19-5H Native Human CK19 Human epithelial ovarian cancer cell culture supernatant N/A
Human KRT19-2235H Recombinant Human KRT19 protein, His&Myc-tagged Insect Cell His&Myc
Human KRT19-382H Native Human KRT19 Human N/A
Human KRT19-001H Recombinant Human KRT19 Protein, His-tagged E. coli His
Human KRT19-0025H Recombinant Human KRT19 Protein HEK293 cells
Human KRT19-360HFL Recombinant Full Length Human KRT19 Protein, C-Flag-tagged Mammalian cells Flag
Human KRT19-4395H Recombinant Human KRT19 Protein (Glu80-Pro241), N-GST tagged E.coli N-GST
Human KRT19-244H Recombinant Human KRT19 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human KRT19-4396H Recombinant Human KRT19 Protein (Met1-Leu400), C-His tagged E.coli C-His
Human KRT19-1265H-B Recombinant Human KRT19 Protein Pre-coupled Magnetic Beads HEK293
Human KRT19-1076H Recombinant Human KRT19 Protein, His-tagged E.coli N-His
Human KRT19-5930HF Recombinant Full Length Human KRT19 Protein, GST-tagged In Vitro Cell Free System GST
Human KRT19-1265H Recombinant Human KRT19 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human KRT19-169H Native Human Cytokeratin 19 Human N/A
Mouse Krt19-5852M Recombinant Mouse Krt19 protein, His-tagged E.coli His
Mouse KRT19-67M Recombinant Mouse KRT19 Protein, His-tagged E.coli His
Mouse Krt19-237M Recombinant Mouse Krt19 protein, His-tagged E. coli His
Mouse Krt19-1284M Recombinant Mouse Krt19 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat Krt19-5853R Recombinant Rat Krt19 protein, His-tagged E.coli His
Rat KRT19-3316R Recombinant Rat KRT19 Protein Mammalian Cell His
Rat KRT19-2972R Recombinant Rat KRT19 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KRT19-2972R-B Recombinant Rat KRT19 Protein Pre-coupled Magnetic Beads HEK293
Chicken KRT19-6567C Recombinant Chicken KRT19 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KRT19 Related Articles
  • KRT19 Related Research Area

KRT19 involved in several pathways and played different roles in them. We selected most pathways KRT19 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KRT19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

KRT19 has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT19 itself. We selected most functions KRT19 had, and list some proteins which have the same functions with KRT19. You can find most of the proteins on our site.

Function Related Protein
structural molecule activityCLDN10;CLDNA;SPRR2A;KRT6A;CLTCB;SNTG1;SPRR2F;TUBB;DESMA

KRT19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT19 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT19.

Ju, JH; Oh, S; et al. Cytokeratin19 induced by HER2/ERK binds and stabilizes HER2 on cell membranes. CELL DEATH AND DIFFERENTIATION 22:665-676(2015).
Guzvic, M; Braun, B; et al. Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes. CANCER RESEARCH 74:7383-7394(2014).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
Are there any clinical trials involving KRT19 protein? 09/29/2022

Yes, there are ongoing clinical trials exploring the use of KRT19 as a biomarker and its potential as a therapeutic target in cancer treatment.

Are there any non-cancer clinical applications of KRT19? 11/10/2020

Yes, KRT19 can also be used as a biomarker in other diseases, such as liver diseases and rheumatoid arthritis.

Are there any targeted therapies based on KRT19 expression? 11/27/2019

Some targeted therapies are being developed that specifically target cancer cells with high KRT19 expression.

Can KRT19 protein be used to predict the prognosis of cancer patients? 01/25/2019

Yes, KRT19 expression levels can provide information about the prognosis of cancer patients, helping in treatment planning.

How is KRT19 protein detected in clinical samples? 04/23/2016

KRT19 protein can be detected using various laboratory techniques, including immunohistochemistry, ELISA, and PCR.

Customer Reviews (3)

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Reviews
08/25/2021

    Such support helps researchers overcome challenges and obtain reliable results.

    11/22/2020

      This flexibility allows researchers to focus on specific aspects of KRT19 protein functionality, regulation, or disease associations, enhancing the relevance and applicability of their work.

      08/26/2020

        Manufacturers might offer customization options, such as different variants or modifications of the KRT19 protein, to cater to specific research requirements.

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