MRPL22

  • Official Full Name

    mitochondrial ribosomal protein L22

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    MRPL22; mitochondrial ribosomal protein L22; 39S ribosomal protein L22, mitochondrial; HSPC158; MRP L25; RPML25; 39S ribosomal protein L22 mitochondrial precursor; L22mt; MRP L22; L25mt; 39S ribosomal protein L25, mitochondrial; MRP-L22; MRP-L25;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MRPL22-145H Recombinant Human MRPL22, His-tagged HEK293 His
Human MRPL22-990H Recombinant Human MRPL22, His-tagged E.coli His
Human MRPL22-4187HCL Recombinant Human MRPL22 293 Cell Lysate HEK293 N/A
Human MRPL22-5567H Recombinant Human MRPL22 Protein, GST-tagged Wheat Germ GST
Human MRPL22-6414HF Recombinant Full Length Human MRPL22 Protein, GST-tagged In Vitro Cell Free System GST
Rat MRPL22-3767R Recombinant Rat MRPL22 Protein Mammalian Cell His
Rat MRPL22-3426R-B Recombinant Rat MRPL22 Protein Pre-coupled Magnetic Beads HEK293
Rat MRPL22-3426R Recombinant Rat MRPL22 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MRPL22-2839R Recombinant Rhesus monkey MRPL22 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MRPL22-2659R Recombinant Rhesus Macaque MRPL22 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MRPL22-2659R-B Recombinant Rhesus Macaque MRPL22 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish MRPL22-6571Z Recombinant Zebrafish MRPL22 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MRPL22 involved in several pathways and played different roles in them. We selected most pathways MRPL22 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RibosomeMRPS15;RPLP0;MRPS7;RPL37A;RPL23;RPL36A-HNRNPH2;RPS10-NUDT3;RPS3;RPS6

MRPL22 has several biochemical functions, for example, poly(A) RNA binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL22 itself. We selected most functions MRPL22 had, and list some proteins which have the same functions with MRPL22. You can find most of the proteins on our site.

Function Related Protein
poly(A) RNA bindingNAT10;TRIM56;GTPBP10;SYF2;NOSIP;EBNA1BP2;NGRN;FMR1;NKRF
structural constituent of ribosomeRPS23;MRPL35;RPS17;RPS4Y1;MRPL42;RPL10A;RPL34;MRPL51;RPL12

MRPL22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL22 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL22.

C1qbp; Ppp2ca; ICT1; MRPL50; MRPL9

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