• Official Full Name

    pim-3 oncogene

  • Overview

    The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is;overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the;regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a;selective advantage in tumorigenesis.
  • Synonyms

    PIM3; pim-3 oncogene; serine/threonine-protein kinase pim-3; serine/threonine kinase Pim-3; pim-3;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Sf21 Insect Cell
  • Sf9 Insect Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human Pim3-116H Active Recombinant Human Pim-3, His-tagged Sf21 Insect Cell His
Human PIM3-2436HF Active Recombinant Full Length Human PIM3 Protein, GST-tagged Insect (sf21) GST 1-326
Human PIM3-3656H Recombinant Human PIM3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PIM3-1461H Recombinant Human PIM3 protein, His & T7-tagged E.coli His/T7 Met1~Leu326 (Accession # Q86V86)
Human PIM3-4508H Recombinant Human PIM3 Protein (Met1-Cys309), N-His tagged E.coli N-His Met1-Cys309
Human PIM3-0923H Recombinant Human PIM3 Protein (L2-L326), Tag Free Insect Cell No tag L2-L326
Human PIM3-4507H Recombinant Human PIM3 Protein (1-309), His tagged E.coli His 1-309
Human PIM3-0924H Recombinant Human PIM3 Protein (L2-L326), GST tagged Insect Cell GST L2-L326
Mouse PIM3-1457M Active Recombinant Mouse PIM3, GST-tagged Sf9 Insect Cell GST Full length
Mouse Pim3-1081M Active Recombinant Mouse Pim3, GST-tagged Sf9 Insect Cell GST Full Length
Mouse Pim3-1081H Recombinant Mouse Pim3 protein, GST-tagged Insect Cell GST Full Length
Mouse Pim3-4870M Recombinant Mouse Pim3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PIM3-4466R Recombinant Rat PIM3 Protein Mammalian Cell His
Rat PIM3-4126R Recombinant Rat PIM3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PIM3-4126R-B Recombinant Rat PIM3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PIM3-3453Z Recombinant Zebrafish PIM3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

PIM3 involved in several pathways and played different roles in them. We selected most pathways PIM3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PIM3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

PIM3 has several biochemical functions, for example, ATP binding, protein binding, protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PIM3 itself. We selected most functions PIM3 had, and list some proteins which have the same functions with PIM3. You can find most of the proteins on our site.

Function Related Protein
protein bindingTNNC2;AHSA2;RMI1;PRDX3;TP53;NLRP3;CD19;TMEM171;COX6B2
protein serine/threonine kinase activityERN2;ACVR1BA;DCLK1;TRIOA;DCLK3;MOS;PIK3CG;PAK2A;PHKG1A

PIM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PIM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PIM3.


Research Area

Related articles

Lopane, C; Goffredo, V; et al. LPA6 promotes growth and tumorigenicity of hepatocellular carcinoma via activation of PIM-3 proto-oncogene kinase. EUROPEAN JOURNAL OF CANCER 50:161-161(2014).
Guo, Q; Lan, PX; et al. Immunotherapy for Hepatoma Using a Dual-Function Vector with Both Immunostimulatory and Pim-3-Silencing Effects. MOLECULAR CANCER THERAPEUTICS 13:1503-1513(2014).
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