pxn Protein, paxillin

pxn

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pxn

Official Full Name paxillin
Background This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the;extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been;described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well;as physiological properties (PMID:9054445).
Synonyms PXN; paxillin; FLJ16691
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • T7
    • N/A
    • Trx
    • S
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PXN-029H Recombinant Human PXN Protein, Trx, His and S-tags-tagged E.coli Trx/His/S
    Human PXN-030H Recombinant Human PXN Protein, His-tagged E.coli His
    Human PXN-2083H Recombinant Human PXN, His-tagged E.coli His
    Human PXN-2413H Recombinant Human Paxillin, GST-tagged E.coli GST
    Human PXN-2651HCL Recombinant Human PXN 293 Cell Lysate HEK293 N/A
    Human PXN-29060TH Recombinant Human PXN E.coli N/A
    Mouse Pxn-1874M Recombinant Mouse Pxn protein, His & T7-tagged E.coli His/T7
    Rat Pxn-1875R Recombinant Rat Pxn protein, His & T7-tagged E.coli His/T7
    Rat PXN-4856R Recombinant Rat PXN Protein Mammalian Cell His
    Chicken PXN-6542C Recombinant Chicken PXN Mammalian Cell His

    pxn involved in several pathways and played different roles in them. We selected most pathways pxn participated on our site, such as Chemokine signaling pathway, VEGF signaling pathway, Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with pxn were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chemokine signaling pathway PIK3R3; CXCR3; CCL3L3; CRK; CCL4; MAP2K1; CCL21B; IKBKG; CCL4L1; WASL
    VEGF signaling pathway MAPK13; PPP3R2; PIK3R3; VEGFAA; PTGS2B; PXNA; AKT2L; RAF1; MAPK3; CASP9
    Focal adhesion TLN2A; PDGFRB; VWF; ITGA10; BIRC3; SRMS; VAV2; BAD; PDGFAA; VAV3
    Leukocyte transendothelial migration BCAR1; VAV3; ACTN3; CXCL12; ACTG1; EZR; CLDN5; CTNNA3; CD99; CYBA
    Regulation of actin cytoskeleton MYLK4; MYL12.2; CDC42L; PDGFD; DIAP3; FGF13B; FGF20B; PTK2AA; BAIAP2A; FGF1
    Bacterial invasion of epithelial cells CD2AP; DNM2; VCL; SHC3; SEPT2; MAD2L2; CBL; ARPC5L; CTNNA3; RHOA
    Viral carcinogenesis RHOA; HIST1H2BK; KRAS; PRKACB; ATP6V0D1; HLA-A; HDAC8; YWHAG; YWHAE; PIK3R5
    Proteoglycans in cancer MMP2; FZD3; PIK3R2; HGF; PRKACA; MAPK1; ARHGEF12; NRAS; CD63; TIMP3

    pxn has several biochemical functions, for example, BH4 domain binding, beta-catenin binding, integrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by pxn itself. We selected most functions pxn had, and list some proteins which have the same functions with pxn. You can find most of the proteins on our site.

    Function Related Protein
    BH4 domain binding PXN
    beta-catenin binding CTNNA3; APC2; SMAD3; TBL1X; DACT2; PTBP3; BCL9L; APC; CDH5; SLC9A3R1
    integrin binding TIMP2; ACTN1; FN1; LAMB2; NOV; FAP; ACTN3; ADAM22; SRC; CTGFA
    protein binding PHYH; NUDT21; EPOR; RLTPR; NPLOC4; PAK2; FAM83A; FBN2; ZNF567; EIF4EBP3
    protein kinase binding CHEK2; PRKAB1; YWHAZ; CDC25B; TSACC; BCL2L14; NCS1; CAMK2N1A; STXBP1; PTK2
    vinculin binding DAG1; SORBS3; SYNM; PXN; CTNNA1; ACTN1; C22orf28; TLN1; DMD; NRAP
    zinc ion binding RARA; FTR54; ADAMDEC1; EWSR1A; ZFP276; ZCCHC10; RNF168; MT1A; NRAP; RAG2

    pxn has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with pxn here. Most of them are supplied by our site. Hope this information will be useful for your research of pxn.

    PTK2; PTPN11; Sorbs1

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