Recombinant Human Paxillin, GST-tagged
Cat.No. : | PXN-2413H |
Product Overview : | Recombinant Human paxillin encoding 356-558 aa was expressed inE. coli.It was fused with a GST tag at the N-terminus. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PXN-2413H |
Description : | Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation. |
Source : | E. coli. |
Presentation : | 100μl purified human Lyn protein at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol without BSA and Sodium Azide. |
Applications : | ELISA•Inhibition Assays• Western Blotting. |
Characterization : | On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 48 kDa (including GST). |
Storage & Stability : | Store vial at -20℃ to -80℃. When stored at the recommended temperature, this protein is stable for 12 months. |
Gene Name : | PXN paxillin [ Homo sapiens ] |
Synonyms : | PXN; paxillin; FLJ16691; Paxillin |
Gene ID : | 5829 |
mRNA Refseq : | NM_001080855 |
Protein Refseq : | NP_001074324 |
UniProt ID : | P49023 |
Chromosome Location : | 12q24 |
MIM : | 602505 |
Pathway : | Chemokine signaling pathway; Focal adhesion; Leukocyte transendothelial migration; Regulation of actin cytoskeleton; VEGF signaling pathway; Cell junction organization; Muscle contraction; Signaling by EGFR |
Function : | metal ion binding; protein binding; vinculin binding; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
Pxn-5268M | Recombinant Mouse Pxn Protein, Myc/DDK-tagged | +Inquiry |
PXN-4515R | Recombinant Rat PXN Protein, His (Fc)-Avi-tagged | +Inquiry |
PXN-01H | Recombinant Human PXN Protein, His-tagged | +Inquiry |
PXN-29060TH | Recombinant Human PXN | +Inquiry |
Pxn-1875R | Recombinant Rat Pxn protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
PXN-2651HCL | Recombinant Human PXN 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket