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  • Official Full Name
  • renal tumor antigen
  • Background
  • This gene belongs to the MAP kinase superfamily. The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein. The encoded protein, which is localized to epithelial cells in the intestinal crypt, may play a role in growth arrest and differentiation of cells of upper crypt and lower villus regions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
  • Synonyms
  • RAGE; renal tumor antigen; renal tumor antigen; MOK protein kinase; MOK; MAPK/MAK/MRK overlapping kinase; renal cell carcinoma antigen (MOK protein kinase); Renal tumor antigen 1; EC 2.7.11.22; RAGE1; RAGE-1; OTTHUMP00000227853; OTTHUMP00000227854; OTTHUMP00000227855

RAGE Related Articles

Sharaf, H; Matou-Nasri, S; et al. Advanced glycation endproducts increase proliferation, migration and invasion of the breast cancer cell line MDA-MB-231. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1852:429-441(2015).
Rodriguez-Teja, M; Gronau, JH; et al. AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival. JOURNAL OF PATHOLOGY 235:581-592(2015).