RPS6KA4 Protein

RPS6KA4

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RPS6KA4

Official Full Name ribosomal protein S6 kinase, 90kDa, polypeptide 4
Background This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Synonyms RPS6KA4; ribosomal protein S6 kinase, 90kDa, polypeptide 4; MSK2; RSK-B; ribosomal protein S6 kinase alpha-4; RSKB; S6K-alpha-4; ribosomal protein kinase B; ribosomal protein S6 kinase alpha 4; 90 kDa ribosomal protein S6 kinase 4; mitogen- and stress-activated protein kinase 2; nuclear mitogen- and stress-activated protein kinase 2;
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect (sf21)
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • His (Fc)-Avi
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RPS6KA4-2434H Recombinant Human RPS6KA4, His-tagged E.coli His Inquiry
    Human RPS6KA4-29913TH Recombinant Human RPS6KA4, His-tagged E.coli His Inquiry
    Mouse Rps6ka4-1062M Recombinant Mouse Ribosomal Protein S6 Kinase, Polypeptide 4, GST-tagged Sf9 Insect Cell GST Inquiry
    Mouse RPS6KA4-14496M Recombinant Mouse RPS6KA4 Protein Mammalian Cell His Inquiry
    Rhesus Macaque RPS6KA4-4029R Recombinant Rhesus monkey RPS6KA4 Protein, His-tagged Mammalian Cell His Inquiry
    Zebrafish RPS6KA4-6718Z Recombinant Zebrafish RPS6KA4 Mammalian Cell His Inquiry
    Human RPS6KA4-2160HCL Recombinant Human RPS6KA4 293 Cell Lysate HEK293 N/A Inquiry
    Rhesus Macaque RPS6KA4-3846R Recombinant Rhesus Macaque RPS6KA4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human RPS6KA4-4448HF Recombinant Full Length Human RPS6KA4 Protein, GST-tagged Insect (sf21) GST Inquiry
    Mouse RPS6KA4-7793M Recombinant Mouse RPS6KA4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human RPS6KA4-2049H Recombinant Human RPS6KA4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Mouse Rps6ka4-5610M Recombinant Mouse Rps6ka4 Protein, Myc/DDK-tagged HEK293T Myc/DDK Inquiry

    RPS6KA4 involved in several pathways and played different roles in them. We selected most pathways RPS6KA4 participated on our site, such as MAPK signaling pathway, TNF signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPS6KA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway TGFBR1A; RAF1; TNF; PPP5C; TGFBR1; PLA2G4AA; FGF11A; MAPK10; FGF13B; TGFB3
    TNF signaling pathway CFLAR; MAPK3; TRAF3; MAP3K7; CCL5; PIK3R1; TNF; IL15; IL1B; CREB3L3

    RPS6KA4 has several biochemical functions, for example, ATP binding, histone kinase activity (H3-S10 specific), magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPS6KA4 itself. We selected most functions RPS6KA4 had, and list some proteins which have the same functions with RPS6KA4. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding RPS6KAL; TTK; ACTA1B; ATP8B5; BSK146; FGR; HSP90AA1.1; UBE2NB; RYK; MAST2
    histone kinase activity (H3-S10 specific) RPS6KA5; RPS6KA4; VRK1
    magnesium ion binding ITPK1; ATP11C; EPHX2; SRPK1; PGM1; IDH2; FARS2; ABL2; CIB2; RRAGC
    mitogen-activated protein kinase p38 binding RPS6KA4; PRMT1; NFATC1; SPAG9; TAB1
    protein binding RAP2B; GLS; SERPINA3; KLHL35; TTPA; FGF10; GDI1; KIAA1217; SNCG; FAM125B
    protein serine/threonine kinase activity CAMK2D2; RAF1; RIOK3; GM7168; MAP2K3; TSSK4; PBK; STK32C; MAP3K10; AAK1
    ribosomal protein S6 kinase activity RPS6KB2; RPS6KA3; RPS6KA1; RPS6KA3B; ALPK2; RPS6KA4; RPS6KA6; RPS6KB1; RPS6KA3A; RPS6KA2

    RPS6KA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPS6KA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPS6KA4.

    MAPK14; MAPK3; pi3p; linkable sunitinib analogue; purvalanol b; midostaurin; SNW1; CDC37; CDC5L

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