RXRA
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Official Full Name
RXRA retinoid X receptor, alpha -
Synonyms
RXRA;retinoid X receptor, alpha;retinoic acid receptor RXR-alpha;NR2B1;nuclear receptor subfamily 2 group B member 1;retinoid X nuclear receptor alpha;FLJ00280;FLJ00318;FLJ16020;FLJ16733;MGC102720
Recombinant Proteins
- Bovine
- Human
- Mouse
- E.coli
- Sf9 Cells
- HEK293
- Mammalian Cells
- His
- GST
- Non
- Flag
- Avi
- Fc
- DDK
- Myc
Involved Pathway
RXRA involved in several pathways and played different roles in them. We selected most pathways RXRA participated on our site, such as PPAR signaling pathway,PIK-Akt signaling pathway,Thyroid hormone signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RXRA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Non-small cell lung cancer | PIK3R2,MAP2K2,PRKCG,CASP9,MAP2K1,KRAS,TGFA,PIK3R5,STK4,RASSF1 |
| Hepatitis C | PPP2CA,MAVS,TNF,CLDN6,PPARA,STAT1,TNFRSF1A,Ifna11,IRF1,CLDN10 |
| Pathways in cancer | NFKB1,TCEB1,PTGER1,ARNT2,Ar,ITGAV,FGF11,MAP2K2,RALGDS,PIK3CG |
| Small cell lung cancer | TP53,LAMB4,MAX,AKT1,ITGA3,TRAF6,ITGA2,TRAF3,LAMC1,COL4A1 |
| PIK-Akt signaling pathway | FGF5,IFNA4,VTN,GNG2,GNG12,MLST8,Fgf15,IFNAR2,IFNA5,GNG13 |
| PPAR signaling pathway | OLR1,ACSL1,CYP27A1,ACADM,ACSL3,ACSL4B,ACSL3A,FABP6,MMP1A,FABP7A |
| Transcriptional misregulation in cancer | Aff1,TGFBR2,IL1R2,FCGR1,CD14,ITGB7,TRAF1,NR4A3,HIST1H3E,SSX2 |
| Non-alcoholic fatty liver disease (NAFLD) | SDHA,PRKAG1,COX6A2,ERN1,NDUFA4L2,UQCRB,NDUFV3,IL6,COX7A2L,NDUFA13 |
| Thyroid cancer | PAX8,HRAS,MAP2K2,RXRG,LEF1,KRAS,TPM3,NTRK1,NCOA4,MAPK3 |
Protein Function
RXRA has several biochemical functions, for example, 9-cis retinoic acid receptor activity,DNA binding,RNA polymerase II regulatory region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RXRA itself. We selected most functions RXRA had, and list some proteins which have the same functions with RXRA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | NPAS1,ZFP516,ZNF35,RXRBA,NR5A5,STAT5B,IKZF2,FOXE1,HLFA,SLC26A3 |
| zinc ion binding | RBM10,BTR18,SOD3A,NR3C2,SIRT6,UBOX5,TRIM23,ZFHX3,ADH1A,RNF217 |
| protein binding | CCDC43,EIF3D,PLEKHG4,ROBO1,ADPRH,POLDIP3,SMAD1,VCL,Mill2,NAA30 |
| protein domain specific binding | DBNL,YWHAE2,EFS,NR0B2,SERPINB1A,HIST1H4H,NFASC,HIST1H4N,ICA1,TACC2 |
| contributes_to vitamin D response element binding | VDR,VDRB,VDRA |
| protein heterodimerization activity | HSPD1,CEBPE,HIST1H4A,SYCP2,TYR,NFKB1,HIST1H3H,PDGFB,TERF1,HER5 |
| 9-cis retinoic acid receptor activity | RXRB,RXRG,RXRGA,RXRAB |
| chromatin DNA binding | EP300,APEX1,H2AFZ,H1F0,XBP1,HIST1H1A,MED1,ACTN4,GRHL2,SMAD3 |
| RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding | NR5A2,NR2E3,VDRA,ESRRA,NR2F6,STAT3,NR1H3,AHR2,NR2F6B,NR5A5 |
Interacting Protein
RXRA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RXRA here. Most of them are supplied by our site. Hope this information will be useful for your research of RXRA.
RARA;NCOA1;MED25;sulindac;PIK3R1
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