Recombinant Human Retinoid X Receptor, Alpha, His-tagged

• Cat.No.: RXRA-5479H
• Product Overview: Recombinant HumanHis-tagged Retinoid X Receptor-alpha containing amino acids 200-462 (LigandBinding Domain) under the control of a T7 promoter.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 200-462 a.a.
• Description: RetinoidX receptor alpha (RXR-alpha), also known as NR2B1 (nuclear receptor subfamily2, group B, member 1) is a nuclear receptor that in humans is encoded by theRXRA gene.
• Form: Liquid in 20 mMTris-HCl, pH 8.0 + 100 mM KCl + 0.2 mM EDTA + 1 mM DTT + 20% glycerol.
• Purity: > 95% asdetermined by SDS-PAGE analysis.
• Applications: In vitrotranscription assays, DNA, and protein-protein interactions assays.
• Storage: Stable for 1 year inworking aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: RXRA
• Pathways: Adipocytokinesignaling pathway; Adipogenesis; Bile secretion; Developmental Biology;Energy Metabolism; Gene Expression; Generic Transcription P; Hepatitis C;IL-3 Signaling Pathway; Metabolism of lipids and lipoproteins; Non-small celllung cancer; Nuclear Receptor transcription pathway; Nuclear Receptors; PPARsignaling pathway; Pathways in cancer

Gene Information

• Gene Name: RXRA retinoid X receptor, alpha[ Homo sapiens ]
• Synonyms: RXRA; retinoidX receptor, alpha; NR2B1; retinoic acid receptor RXR-alpha;OTTHUMP00000022510; retinoid X nuclear receptor alpha; nuclear receptorsubfamily 2 group B member 1; Retinoic acid receptor RXR-alpha; Nuclear receptor subfamily 2 group B member 1; Retinoid Xreceptor alpha
• Gene ID: 6256
• mRNA Refseq: NM_002957
• Protein Refseq: NP_002948
• MIM: 180245
• UniProt ID: P19793
• Chromosome Location: 9q34
• Function: DNA binding;double-stranded DNA binding; enzyme binding; ligand-regulated transcriptionfactor activity; metal ion binding; protein binding; proteinheterodimerization activity; receptor activity; retinoic acid receptoractivity; retinoic acid-responsive element binding; retinoid-X receptoractivity; sequence-specific DNA binding; sequence-specific DNA bindingtranscription factor activity; steroid binding; steroid hormone receptoractivity; transcription coactivator activity