SHC1

  • Official Full Name

    SHC1 SHC (Src homology 2 domain containing) transforming protein 1
  • Synonyms

    SHC1;SHC (Src homology 2 domain containing) transforming protein 1;SHC, SHC (Src homology 2 domain containing) transforming protein 1;SHC-transforming protein 1;p66;SH2 domain protein C1;SHC-transforming protein 3;SHC-transforming protein A;SHC (Src homology 2 domain-containing) transforming protein 1;SHC;SHCA;FLJ26504

Recombinant Proteins

  • Human
  • Mouse
  • Rhesus macaque
  • Chicken
  • E.coli
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • Non
  • DDK
  • Myc
  • Avi
  • Fc
  • MBP
Cat.# Product name Source (Host) Species Tag Protein Length Price
SHC1-2654H Recombinant Human SHC1, GST-tagged E.coli Human GST 1-169AA
SHC1-15090M Recombinant Mouse SHC1 Protein Mammalian Cells Mouse His
SHC1-30065TH Recombinant Human SHC1, His-tagged E.coli Human His 474 amino acids
SHC1-3579H Recombinant Human SHC1, His-tagged E.coli Human His
SHC1-4192R Recombinant Rhesus monkey SHC1 Protein, His-tagged Mammalian Cells Rhesus macaque His
SHC1-5568C Recombinant Chicken SHC1 Mammalian Cells Chicken His
SHC1-1862HCL Recombinant Human SHC1 293 Cell Lysate HEK293 Human Non
SHC1-1005H Recombinant Human SHC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
SHC1-4008R Recombinant Rhesus Macaque SHC1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
SHC1-4008R-B Recombinant Rhesus Macaque SHC1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
Shc1-5854M Recombinant Mouse Shc1 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
SHC1-6283H Recombinant Human SHC1 Protein (Glu272-His559), N-His tagged E.coli Human His Glu272-His559
SHC1-8141M Recombinant Mouse SHC1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
SHC1-8141M-B Recombinant Mouse SHC1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
SHC1-9383H Recombinant Human SHC1 protein, MBP&His-Avi-tagged, Biotinylated E.coli Human Avi&His&MBP 150-320aa

    Involved Pathway

    SHC1 involved in several pathways and played different roles in them. We selected most pathways SHC1 participated on our site, such as ErbB signaling pathway,Ras signaling pathway,Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MicroRNAs in cancer NRAS,BMI1,EZH2,SOS1,TRIM71,NOTCH4,ROCK1,CCNG1,DNMT3B,TPM1
    Insulin signaling pathway G6PC,IRS4,INS,PDPK1B,PRKAG3B,PHKG1A,EIF4E2RS1,PRKAG2,MKNK2B,PPARGC1A
    Focal adhesion SEPP1,LAMC2,MYL12.1,ACTB,FN1A,RHOAB,ITGA3,RHOB,LAMA5,RHOAA
    Bacterial invasion of epithelial cells BCAR1,SEPT9,PIK3R5,ELMO1,SRC,ITGB1,GAB1,VCL,CDH1,WASL
    Alcoholism HIST2H2BE,CALM1,HIST3H2BB,DRD1,HDAC11,MAOB,HDAC7A,HIST1H2BJ,GRIN2A,HIST2H4
    Neurotrophin signaling pathway AKT2,GSK3B,GAB1,RELA,MAGED1,PIK3CA,PIK3R1,YWHAE,MAPK9,HRAS
    Glioma PIK3R2,PRKCG,CALML3,PIK3CA,CALM4,SHC2,PDGFRB,RAF1,TP53,NRAS
    Natural killer cell mediated cytotoxicity SYK,TNFRSF10A,ICAM2,KIR2DS5,SHC2,RAC2,PLCG1,PPP3CB,SH2D1B,FASLG
    Chronic myeloid leukemia TGFB2,PIK3CG,SMAD3,TGFBR1,CRK,ARAF,BRAF,GRB2,CBLC,NFKB1

    Protein Function

    SHC1 has several biochemical functions, for example, ephrin receptor binding,epidermal growth factor receptor binding,insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHC1 itself. We selected most functions SHC1 had, and list some proteins which have the same functions with SHC1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding KREMEN1,FNTB,RCC1,ACP1,CSNK1G2,C18orf1,TANK,TRIM43,NBL1,HHEX
    phospholipid binding PSD2,NR5A1,ABCG1,NBEAL2,PLA2G7,PRKCI,SYT14,APOA1,PACSIN1A,APOA2
    protein kinase binding KIF20A,PTK2,PPP1R12C,CHRNA7,POLA1,PRKACA,PAK2,PDGFRB,TRAF2,CDH2
    epidermal growth factor receptor binding SNX2,ERBB4,TNK2,PLSCR1,AGR2,Fert2,EPGN,TGFA,CBLC,HBEGFB
    insulin receptor binding DOK5,SNX2,INS2,PTPN11,PIK3R1,PDPK1,INSL3,IGF2,DOK1B,DOK4
    neurotrophin TRKA receptor binding GRB2,FRS2,EFNA5,NGFR,PIK3R1,PLCG1
    insulin-like growth factor receptor binding YWHAG,YWHAH,INS2,INSR,INSL4,PIK3R1,Ren1,GNAS,IGF2A,IGF3
    protein tyrosine kinase activity IGF1RA,MET,LTK,CSK,MAP2K4,TTN,MAP2K7,ERBB3A,HCK,RET
    protein phosphatase 2A binding ENSA,ENSAA,ARPP19,PTPN1,PPP2R4,AKT1,MAPT,PPME1,TP53,STRN

    Interacting Protein

    SHC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC1.

    GRB2

    SHC1 Related Signal Pathway

    Resources

    References

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