• Official Full Name

    SHC1 SHC (Src homology 2 domain containing) transforming protein 1

  • Synonyms

    SHC1; SHC (Src homology 2 domain containing) transforming protein 1; SHC, SHC (Src homology 2 domain containing) transforming protein 1; SHC-transforming protein 1; p66; SH2 domain protein C1; SHC-transforming protein 3; SHC-transforming protein A; SHC (Src homology 2 domain-containing) transforming protein 1; SHC; SHCA; FLJ26504;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
  • MBP
  • C
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SHC1-3579H Recombinant Human SHC1, His-tagged E.coli His
Human SHC1-2654H Recombinant Human SHC1, GST-tagged E.coli GST 1-169AA
Human SHC1-30065TH Recombinant Human SHC1, His-tagged E.coli His 474 amino acids
Human SHC1-1862HCL Recombinant Human SHC1 293 Cell Lysate HEK293 N/A
Human SHC1-1005H Recombinant Human SHC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SHC1-6283H Recombinant Human SHC1 Protein (Glu272-His559), N-His tagged E.coli N-His Glu272-His559
Human SHC1-9383H Recombinant Human SHC1 protein, MBP&His-Avi-tagged, Biotinylated E.coli N-MBP&C-His-Avi 150-320aa
Mouse SHC1-15090M Recombinant Mouse SHC1 Protein Mammalian Cell His
Mouse Shc1-5854M Recombinant Mouse Shc1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SHC1-8141M Recombinant Mouse SHC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SHC1-8141M-B Recombinant Mouse SHC1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SHC1-4192R Recombinant Rhesus monkey SHC1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SHC1-4008R Recombinant Rhesus Macaque SHC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SHC1-4008R-B Recombinant Rhesus Macaque SHC1 Protein Pre-coupled Magnetic Beads HEK293
Chicken SHC1-5568C Recombinant Chicken SHC1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • SHC1 Related Signal Pathway

SHC1 involved in several pathways and played different roles in them. We selected most pathways SHC1 participated on our site, such as ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chemokine signaling pathwaySOS1;PRKACB;CCR8;CCL28;PRKACG;CXCL9;GNAI2;GRK7;MAPK3
Phospholipase D signaling pathwayKITLG;KIT;TSC2;TSC1;ARF6;INS1;IL-8;AVPR1B;RRAS2
Natural killer cell mediated cytotoxicityPIK3R3;SHC4;FYN;IFNA8;PLCG1;MAPK3;KIR3DL2;CD244;TNFRSF10B
Neurotrophin signaling pathwayPLCG1;CAMK2D;RHOA;AKT1;RELA;NTRK1;MAPK7;NFKBIA;MAPK9
Insulin signaling pathwayMAP2K2;RHOQ;PPP1CAA;PRKAG1;PTPN1;PPP1CAB;BADB;RAF1A;G6PC2
Estrogen signaling pathwaySHC4;RAF1;KCNJ3;NRAS;HSPA1B;MAPK3;SOS1;HSP90AB1;GNAS
Prolactin signaling pathwayCSN2;CCND1;AKT1;SOCS6;GSK3B;MAPK8;SHC1;GRB2;SHC4
Bacterial invasion of epithelial cellsCTNNA1;RHOA;ITGB1;DOCK1;PTK2;PIK3R2;DNM3;SHC3;ARPC4
Chronic myeloid leukemiaIKBKB;SHC1;NFKBIA;TP53;CTBP2;STAT5A;MAPK3;BCL2L1;ABL1

SHC1 has several biochemical functions, for example, ephrin receptor binding, epidermal growth factor receptor binding, insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHC1 itself. We selected most functions SHC1 had, and list some proteins which have the same functions with SHC1. You can find most of the proteins on our site.

Function Related Protein
ephrin receptor bindingEFNA3;CDK5R1;CRK;CDK5;EFNA1A;NTRK1;NTRK3;SRC;FYN
epidermal growth factor receptor bindingBTC;ARF4;YES1;AREG;FER;ERBB4;LINGO1;TNK2;AGR2
insulin receptor bindingDOK2;FRS3;PIK3R1;FRS2;GRB10;INS2;IGF1;DOK5;DOK1
insulin-like growth factor receptor bindingIGF1;Ren1;YWHAH;GNAS;SOCS2;INS;IGF2A;IGF3;SHC1
neurotrophin TRKA receptor bindingGRB2;PIK3R1;SHC1;FRS2;NGFR;EFNA5;PLCG1
phosphotyrosine bindingCBL;STAP1;GRB2;MAPK3;CBLB;ACP2;LDLRAP1;PTPN3;ZAP70
protein kinase bindingCD4;CCNL1;CD8A;DNM1;RPS3;TBC1D14;AKAP5;PRKAB1;CCNK
protein phosphatase 2A bindingSMG5;PTPN1;ANKLE2;ENSA;ENSAA;GRIN3A;FOXO1;STRN;CTTNBP2NL
protein tyrosine kinase activityCSF1RA;KITA;BMX;NTRK3A;IGF1R;ZAP70;FGFR2;ERBB3B;MAP3K9
transmembrane receptor protein tyrosine kinase adaptor activitySH2B2;GAB2;PIK3R1;FRS2;TRAT1;IRS1;SHC1;DOK2;STAP1

SHC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC1.


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