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Official Full Name SHC1 SHC (Src homology 2 domain containing) transforming protein 1
Synonyms SHC1; SHC (Src homology 2 domain containing) transforming protein 1; SHC, SHC (Src homology 2 domain containing) transforming protein 1; SHC-transforming protein 1; p66; SH2 domain protein C1; SHC-transforming protein 3; SHC-transforming protein A; SHC (Src homology 2 domain-containing) transforming protein 1; SHC; SHCA; FLJ26504;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SHC1-1005H Recombinant Human SHC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human SHC1-1862HCL Recombinant Human SHC1 293 Cell Lysate HEK293 N/A
    Human SHC1-2654H Recombinant Human SHC1, GST-tagged E.coli GST
    Human SHC1-30065TH Recombinant Human SHC1, His-tagged E.coli His
    Human SHC1-3579H Recombinant Human SHC1, His-tagged E.coli His
    Mouse SHC1-15090M Recombinant Mouse SHC1 Protein Mammalian Cell His
    Mouse Shc1-5854M Recombinant Mouse Shc1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rhesus Macaque SHC1-4192R Recombinant Rhesus monkey SHC1 Protein, His-tagged Mammalian Cell His
    Chicken SHC1-5568C Recombinant Chicken SHC1 Mammalian Cell His

    SHC1 involved in several pathways and played different roles in them. We selected most pathways SHC1 participated on our site, such as ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ErbB signaling pathway EGFRA; MAPK8; AKT2L; PAK2A; SHC2; NRG1; RAF1; GAB1; NCK2; PAK6B
    Ras signaling pathway RAB5B; Fgf15; MAPK10; PRKCB; SHC3; RAC2; ANGPT2; PDGFB; RASGRP3; RASA4
    Chemokine signaling pathway CCL2; IKBKG; PREX1; SHC3; PXN; AMCF-II; CX3CL1; CDC42; CCL17; CCL14
    Phospholipase D signaling pathway INS; PLA2G4D; DGKZ; INSR; PIK3R1; PDGFA; CXCR2; PLD2; PDGFD; PIP5K1A
    Focal adhesion VTN; MYL2B; RAC1B; ITGA6; PPP1R12B; RHOB; PARVB; MET; RAF1B; COL4A1
    Natural killer cell mediated cytotoxicity PIK3R2; PTK2B; MICA; NCR3; FCGR3B; RAET1G; SAMD3; PRKCG; NCR1; BRAF
    Neurotrophin signaling pathway Fasl; SOS1; PLCG2; KIDINS220; BDNF; PRDM4; TP53; MAPK12; PSEN1; MAP3K3
    Insulin signaling pathway TRIP10A; GYS2; RPS6KB1B; INS2; PPP1R3CA; PRKAG2; RAF1; PPP1CB; GSK3B; FOXO1B
    Estrogen signaling pathway SP1; PIK3R1; ATF6B; KCNJ5; NRAS; FKBP4; PIK3CB; MMP2; PLCB3; CREB3L1
    Prolactin signaling pathway MAPK8; PIK3R3; STAT5B; RAF1; AKT2; MAPK10; PRLR; CCND1; NFKB1; ESR2
    Bacterial invasion of epithelial cells VCL; FN1; DNM3; ITGB1; CLTC; PIK3CD; ELMO2; DNM1; SEPT11; PIK3R2
    MicroRNAs in cancer PDGFRA; PDGFA; Abcb1b; TIMP3; TRP63; DNMT1; BMI1; GLS; VEGFA; CCNG1
    Chronic myeloid leukemia MECOM; MAPK3; TGFB2; SOS1; SHC1; PIK3R2; RB1; NRAS; ARAF; NFKB1

    SHC1 has several biochemical functions, for example, ephrin receptor binding, epidermal growth factor receptor binding, insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHC1 itself. We selected most functions SHC1 had, and list some proteins which have the same functions with SHC1. You can find most of the proteins on our site.

    Function Related Protein
    ephrin receptor binding ANKS1B; SIPA1L1; EFNB3; NTRK1; EFNB2; GRB2; EFNB1; SHC1; EFNA5; SRC
    epidermal growth factor receptor binding ATXN2; SNX2; EREG; GRB2; TGFA; EPGN; LINGO1; BTC; ERBB4; SNX1
    insulin receptor binding DOK5; FRS3; GRB10; PHIP; DOK1B; SNX4; PDPK1; INS; INS2; PTPN11
    insulin-like growth factor receptor binding Ren1; REN; INS2; INS; IGF2; IGF1; IRS1; YWHAH; YWHAG; INSR
    neurotrophin TRKA receptor binding PLCG1; PIK3R1; EFNA5; GRB2; NGFR; FRS2; SHC1
    phospholipid binding TEC; SMURF1; PON1; APOC3; PAFAH2; NSMAF; SPTBN1; PLEKHA3; SNCA; ESYT1
    phosphotyrosine binding LDLRAP1; CBL; MAPK1; STAP1; CBLC; GRB2; SHC1; ZAP70; MAPK3; PTPN3
    protein binding RAD9A; DCTPP1; ZNF329; FBXO44; KIAA0408; FAT4; SIX1; C8orf74; BAZ2A; PVR
    protein kinase binding TSACC; USF1; SKI; WAS; CNTLN; FGFR1OP; PEBP1; TRP53; PDGFRB; B4GALT1
    protein phosphatase 2A binding BCL2; ENSAA; ENSA; STRN4; PPP2R2A; EIF4EBP1; HMGCR; RPS6KB1; MASTL; SMG7
    protein tyrosine kinase activity MAP3K11; TESK2; FGFR1A; MAP2K3; FER; FGFR4; KDR; TESK1; CSF1RA; SRC
    transmembrane receptor protein tyrosine kinase adaptor activity TRAT1; SHC1; DOK2; PIK3R1; GAB2; IRS1; BLNK; SH2B2; STAP1; FRS2

    SHC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC1.


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