• Official Full Name

    sortilin-related receptor, L(DLR class) A repeats containing

  • Overview

    This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10);domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also;contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded protein is translated as a;preproprotein and likely plays roles in endocytosis and sorting. There may be an association between expression of;this locus and Alzheimers Disease.
  • Synonyms

    SORL1; sortilin-related receptor, L(DLR class) A repeats containing; C11orf32, chromosome 11 open reading frame 32 , sortilin related receptor, L(DLR class) A repeats containing; sortilin-related receptor; gp250; LR11; LRP9; SorLA; SorLA 1; C11orf32; FLJ21930; FLJ39258; LDLR relative with 11 ligand binding repeats; LDLR relative with 11 ligand-binding repeats; Low density lipoprotein receptor relative with 11 ligand binding repeats; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LR 11; LRP 9; Mosaic protein LR11; SORL 1; SORL_HUMAN; SorLA-1; Sortilin related receptor; Sortilin related receptor L(DLR class) A repeats containing; Sorting protein related receptor containing LDLR class A repeats; Sorting protein-related receptor containing LDLR class A repeats; OTTHUMP00000231797; sortilin-related receptor, L(DLR class) A repeats-containing; low-density lipopro;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E. coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SORL1-29617TH Recombinant Human SORL1 Wheat Germ N/A
Human SORL1-01H Active Recombinant Human SORL1 Protein, His-tagged HEK293 His
Human SORL1-801H Recombinant Human SORL1 protein, His-tagged E. coli His
Mouse SORL1-15763M Recombinant Mouse SORL1 Protein Mammalian Cell His
Mouse SORL1-8576M-B Recombinant Mouse SORL1 Protein Pre-coupled Magnetic Beads HEK293
Mouse SORL1-8576M Recombinant Mouse SORL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SORL1 Related Research Area

SORL1 involved in several pathways and played different roles in them. We selected most pathways SORL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SORL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

SORL1 has several biochemical functions, for example, ADP-ribosylation factor binding, beta-amyloid binding, low-density lipoprotein particle binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SORL1 itself. We selected most functions SORL1 had, and list some proteins which have the same functions with SORL1. You can find most of the proteins on our site.

Function Related Protein
ADP-ribosylation factor bindingRAB11FIP4;SORL1;RAB11FIP4B;RAB11FIP4A;GRASP;ADCYAP1R1;GGA2;RAB11FIP3;ZFP652
beta-amyloid bindingApba1;GPRASP2;SORL1;APBA2;BACE1;TM2D1;APBB3;APOA1;FBXO2
low-density lipoprotein particle bindingSCARF1;LDLR;LIPC;MSR1;THBS1;COLEC12;PCSK9;CRP;CDH13
transmembrane signaling receptor activityLYVE1;CD3E;TLR6;KLRC2;TNFRSF10C;FZD7A;P2RX6;CLEC2D;KLRF1

SORL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SORL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SORL1.

GGA2; GGA1; dimyristoylphosphatidyl choline; heparin; calcium(2+); DYRK3; APOE; LRPAP1; APOA5

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