UGT2B17
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Official Full Name
UDP glucuronosyltransferase 2 family, polypeptide B17
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Background
This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis. -
Synonyms
UGT2B17; UDP glucuronosyltransferase 2 family, polypeptide B17; UDP glycosyltransferase 2 family, polypeptide B17; UDP-glucuronosyltransferase 2B17; C19 steroid specific UDP glucuronosyltransferase; C19 steroid specific UDPGT; UDB17; UDP glucuronosyltransferase 2B17; UDPGT 2B17; C19-steroid-specific UDPGT; UDP glycosyltransferase 2 family, member B17; UDP-glucuronyltransferase, family 2, beta-17; C19-steroid-specific UDP-glucuronosyltransferase; UDPGT2B17;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | UGT2B17-173H | Recombinant Human UGT2B17 Full Length Transmembrane protein, His-tagged | In vitro E. coli expression system | His |
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Rat | UGT2B17-6435R | Recombinant Rat UGT2B17 Protein | Mammalian Cell | His |
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Rat | UGT2B17-6091R-B | Recombinant Rat UGT2B17 Protein Pre-coupled Magnetic Beads | HEK293 |
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Rat | UGT2B17-6091R | Recombinant Rat UGT2B17 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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- UGT2B17 Related Articles
Izukawa, T; Nakajima, M; et al. Quantitative Analysis of UDP-Glucuronosyltransferase (UGT) 1A and UGT2B Expression Levels in Human Livers. DRUG METABOLISM AND DISPOSITION 37:1759-1768(2009).
Chouinard, S; Yueh, MF; et al. Inactivation by UDP-glucuronosyltransferase enzymes: The end of androgen signaling. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 109:247-253(2008).
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