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  • Official Full Name
  • alkaline ceramidase 2
  • Background
  • The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor,;sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate;sphingosine (Xu et al., 2006 (PubMed 16940153)).
  • Synonyms
  • ACER2; alkaline ceramidase 2; ASAH3L, N acylsphingosine amidohydrolase 3 like; FLJ41587; haCER2; alkCDase 2; alkaline CDase 2; ceramide hydrolase; ASAH3L; ALKCDase2
Cat.#:ASAH3L-879HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ASAH3L protein, GST-tagged
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ACER2 Related Articles

Sasaki, H; Toyomura, K; et al. Regulation of alkaline ceramidase activity by the c-Src-mediated pathway. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 550:12-19(2014).
Snider, AJ; Wu, BX; et al. Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease. PROSTAGLANDINS & OTHER LIPID MEDIATORS 99:124-130(2012).