Recombinant Full Length Human ACER2 Protein, GST-tagged

• Cat.No.: ACER2-1454HF
• Product Overview: Human ASAH3L full-length ORF ( AAH92487.1, 1 a.a. - 226 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 [PubMed 16940153]).[supplied by OMIM, Jul 2010]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 52.1 kDa
• Protein Length: 226 amino acids
• AA Sequence: MCLFRQYATC FNSGIYLIWT LLVVVGIGSV YFHATLSFLG QMLDELAVLW VLMCALAMWF PRRYLPKIFR NDRGRFKVVV SVLSAVTTCL AFVKPAINNI SLMTLGVPCT ALLIAELKRC DNMRVFKLGL FSGLWWTLAL FCWISDRAFC ELLSSFNFPY LHCMWHILIC LAAYLGCVCF AYFDAASEIP EQGPVIKFWP NEKWAFIGVP YVSLLCANKK SSVKIT
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ACER2 alkaline ceramidase 2 [ Homo sapiens ]
• Official Symbol: ACER2
• Synonyms: ACER2; alkaline ceramidase 2; ASAH3L, N acylsphingosine amidohydrolase 3 like; FLJ41587; haCER2; alkCDase 2; alkaline CDase 2; ceramide hydrolase; ASAH3L; ALKCDase2
• Gene ID: 340485
• mRNA Refseq: NM_001010887
• Protein Refseq: NP_001010887
• MIM: 613492
• UniProt ID: Q5QJU3