BST2 Protein, bone marrow stromal cell antigen 2


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Official Full Name bone marrow stromal cell antigen 2
Background Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis.
Synonyms BST2; bone marrow stromal cell antigen 2; bone marrow stromal antigen 2; CD317; tetherin; BST-2; NPC-A-7; HM1.24 antigen
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Bst2-300M Recombinant Mouse BST2 Protein, His-tagged HEK293 His
    Human BST2-1242HCL Recombinant Human BST2 cell lysate Human Cell N/A
    Human BST2-26108TH Recombinant Human BST2 Wheat Germ N/A
    Human BST2-26110TH Recombinant Human BST2 Wheat Germ N/A
    Human BST2-2832H Recombinant Human BST2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human BST2-3569H Recombinant Human BST2, His-tagged E.coli His
    Human BST2-8582H Recombinant Human BST2, Fc tagged Human Cell Fc
    Human BST2-8583H Recombinant Human BST2, His tagged Human Cell His
    Mouse BST2-1623MCL Recombinant Mouse BST2 cell lysate Human Cell N/A
    Mouse BST2-954M Recombinant Mouse BST2 Protein, Fc-tagged HEK293 Fc
    Rat BST2-1025R Recombinant Rat BST2 Protein Mammalian Cell His
    Rhesus Macaque BST2-572R Recombinant Rhesus monkey BST2 Protein, His-tagged Mammalian Cell His

    BST2 involved in several pathways and played different roles in them. We selected most pathways BST2 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with BST2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine Signaling in Immune system KLB; FRS2; FGF20A; NEFLB; NUP50; PELI3; EDARADD; DUSP1; IFI35; UBE2L6
    Immune System KLRF1; TIRAP; CTLA4; KIF5B; TRIM45; CD207; CLEC2H; IFIT11; CASP4; FCGR1B
    Interferon Signaling TRIM5; TRIM31; IFIT10; USP18; IFIT3; ISG20; EIF4G2; TRIM45; IFIT11; FCGR1B
    Interferon alpha/beta signaling IRF2; IFIT2; XAF1; IFI35; IFI27; USP18; IRF9; ISG20; IFIT3; IFITM2

    BST2 has several biochemical functions, for example, metalloendopeptidase inhibitor activity, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BST2 itself. We selected most functions BST2 had, and list some proteins which have the same functions with BST2. You can find most of the proteins on our site.

    Function Related Protein
    metalloendopeptidase inhibitor activity RECK; NGF; WFIKKN1; BST2; SPOCK1; WFIKKN2; TIMP1; TIMP2; COL4A3; TIMP2A
    poly(A) RNA binding MRPL42; ARL6IP4; LUZP4; PRPF8; NPM1; LARP4; RALYL; EXOSC10; DHX37; UBE2O
    protein binding IL5RA; SCG2; BSCL2; MUTED; NPHP3; HSD17B10; MLF1; GSG2; RPS20; PIK3CG
    protein homodimerization activity EPHX2; PTPRE; PDGFC; FGFR1; BCL2L2; PDK2; ERBB4; TARBP2; Trl; TIMM9
    signal transducer activity TAAR12H; SH2B1; PTGER2B; ILK; HTR1D; TAAR8C; OPN1SW1; GNB1; TAS2R140; TAAR14L

    BST2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BST2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BST2.

    vpu; Ap1m1; vpu; HARS2; HAGH; yycF; Bmpr1a; TMPO; CAPZA2; Ptpn23; Chmp4b

    Fang, KH; Kao, HK; et al. Overexpression of BST2 Is Associated With Nodal Metastasis and Poorer Prognosis in Oral Cavity Cancer. LARYNGOSCOPE 124:E354-E360(2014).
    Pham, TNQ; Lukhele, S; et al. HIV Nef and Vpu protect HIV-infected CD4+T cells from antibody-mediated cell lysis through down-modulation of CD4 and BST2. RETROVIROLOGY 11:-(2014).

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