bst2
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  • Official Full Name
  • bone marrow stromal cell antigen 2
  • Background
  • Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis.
  • Synonyms
  • BST2; bone marrow stromal cell antigen 2; bone marrow stromal antigen 2; CD317; tetherin; BST-2; NPC-A-7; HM1.24 antigen
Cat.#:Bst2-300MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse BST2 Protein, His-tagged
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Cat.#:BST2-2832HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human BST2 Protein, MYC/DDK-tagged
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Cat.#:BST2-3569HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BST2, His-tagged
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Cat.#:BST2-26108THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human BST2
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Cat.#:BST2-26110THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human BST2
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Cat.#:BST2-8582HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human BST2, Fc tagged
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Cat.#:BST2-8583HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human BST2, His tagged
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Cat.#:BST2-954MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse BST2 Protein, Fc-tagged
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Cat.#:BST2-1025RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat BST2 Protein
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Cat.#:BST2-572RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey BST2 Protein, His-tagged
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Cat.#:BST2-1242HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human BST2 cell lysate
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Cat.#:BST2-1623MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse BST2 cell lysate
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Involved Pathway

BST2 involved in several pathways and played different roles in them. We selected most pathways BST2 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with BST2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine Signaling in Immune system
IRAK3; FGF18B; IFIT3; KPNA4; SPTBN1; KPNA3; TRIM14; IFITM3; IFIT8; NEFLB
Immune System
LILRB2; EIF4E3; CLEC2B; DEFB104A; RNF14; BTR06; ISG20; RAPGEF4; RNF41; WIPF2
Interferon Signaling
TRIM46; GBP4; TRIM8; EIF4E3; EIF4G2; TRIM3; TRIM2; MX2; EIF4G2A; IFIT8
Interferon alpha/beta signaling
IFIT2; IRF4; IFI6; IRF6; IFI35; USP18; IRF9; IFIT3; IFI27; GBP2

Protein Function

BST2 has several biochemical functions, for example, metalloendopeptidase inhibitor activity, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BST2 itself. We selected most functions BST2 had, and list some proteins which have the same functions with BST2. You can find most of the proteins on our site.
Function
Related Protein
Function metalloendopeptidase inhibitor activity
Related Protein TIMP2; COL4A3; NGF; TIMP4; TIMP1; FETUB; BST2; TIMP2B; TIMP3; TIMP2A
Function poly(A) RNA binding
Related Protein TPR; PIGC; RPL11; PPHLN1; CROP; THOC4; RPS26; RP9; DUT; SRPR
Function protein binding
Related Protein IFT88; TTC33; POLR1A; PHF7; CTTN; ASUN; ZCCHC10; TTC23L; CCNB1; SNAP91
Function protein homodimerization activity
Related Protein CDH13; CSF1; FLT3LG; XCL1; DST; NETO2; AGXT; DPP4; SMAD2; DARS2
Function signal transducer activity
Related Protein GNRHR3; DRD1B; CBLC; OPN4.1; OPN1LW2; SH2B3; PLCB3; PLEKHG5; LPAR6; DRD2L

Interacting Protein

BST2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BST2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BST2.
vpu; Ap1m1; vpu; HARS2; HAGH; yycF; Bmpr1a; TMPO; CAPZA2; Ptpn23; Chmp4b

BST2 Related Articles

Fang, KH; Kao, HK; et al. Overexpression of BST2 Is Associated With Nodal Metastasis and Poorer Prognosis in Oral Cavity Cancer. LARYNGOSCOPE 124:E354-E360(2014).
Pham, TNQ; Lukhele, S; et al. HIV Nef and Vpu protect HIV-infected CD4+T cells from antibody-mediated cell lysis through down-modulation of CD4 and BST2. RETROVIROLOGY 11:-(2014).