Active Recombinant Human BST2 Protein, Fc tagged

• Cat.No.: BST2-18H
• Product Overview: The recombinant human CD317-Fc is expressed as a 349-amino acid protein consisting of Ser50-Ser161 region of CD317 and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 50-161 aa
• Description: Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis.
• AASequence: SEACRDGLRAVMECRNVTHLLQQELTEAQKGFQDVEAQAATCNHTVMALMASLDAEKAQGQKKVEELEGEITTLNHKLQDASAEVERLRRENQVLSVRIADKKYYPSSQDSSTTENLYFQGSTGTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
• Molecular Mass: 39.1 kDa
• Bio-activity: Binds to its ligand human ILT7 protein and blocks its signaling activity.
• Calculated PI: 5.97
• Calculated extinction coefficients (M-1 cm-1, at 280nm): 40380
• Endotoxin: < 0.1 EU/μg of purified recombinant protein determined by the LAL method
• Purity: >95% judged by SDS-PAGE under reducing condition
• Storage Buffer: Sterile PBS pH7.4 (carrier & preservative free).
• Concentration: 0.5 mg/mL

Gene Information

• Gene Name: BST2 bone marrow stromal cell antigen 2 [ Homo sapiens (human) ]
• Official Symbol: BST2
• Synonyms: BST2; BST-2; Tetherin; CD317; bone marrow stromal cell antigen 2; HM1.24; bone marrow stromal antigen 2; BST-2; HM1.24 antigen; NPC-A-7; antiviral factor tetherin
• Gene ID: 684
• mRNA Refseq: NM_004335
• Protein Refseq: NP_004326
• MIM: 600534
• UniProt ID: Q10589