CDC42EP2 Protein, CDC42 effector protein (Rho GTPase binding) 2


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Official Full Name CDC42 effector protein (Rho GTPase binding) 2
Background CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control.
Synonyms CDC42EP2; CDC42 effector protein (Rho GTPase binding) 2; cdc42 effector protein 2; BORG1; CEP2; CRIB containing BOGR1 protein; Binder of Rho GTPases 1; CRIB-containing BOGR1 protein; OTTHUMP00000231608
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Cdc42ep2-254M Recombinant Mouse Cdc42ep2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human CDC42EP2-0945H Recombinant Human CDC42EP2 Protein, GST-Tagged Wheat Germ GST
    Human CDC42EP2-7653HCL Recombinant Human CDC42EP2 293 Cell Lysate HEK293 N/A
    Mouse CDC42EP2-3144M Recombinant Mouse CDC42EP2 Protein Mammalian Cell His
    Rat CDC42EP2-1281R Recombinant Rat CDC42EP2 Protein Mammalian Cell His
    Rhesus Macaque CDC42EP2-764R Recombinant Rhesus monkey CDC42EP2 Protein, His-tagged Mammalian Cell His
    Zebrafish CDC42EP2-2198Z Recombinant Zebrafish CDC42EP2 Mammalian Cell His

    CDC42EP2 involved in several pathways and played different roles in them. We selected most pathways CDC42EP2 participated on our site, such as MAPK family signaling cascades, MAPK6/MAPK4 signaling, Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC42EP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK family signaling cascades CDC42EP5; MAPK4; IGF2BP1; SEPT7; CDC42EP1B; MAPK6; CDC42EP3; CDC42EP2
    MAPK6/MAPK4 signaling CDC42EP3; CDC42EP2; IGF2BP1; SEPT7; MAPK4; MAPK6; CDC42EP5; CDC42EP1B
    Signal Transduction RSPO4; SST; ADM2A; RHOUA; TAX1BP3; JUPA; GAL; RBP1; SH2B3; DEPDC1B

    CDC42EP2 has several biochemical functions, for example, GTP-Rho binding, GTPase activator activity, opioid peptide activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC42EP2 itself. We selected most functions CDC42EP2 had, and list some proteins which have the same functions with CDC42EP2. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activator activity GARNL3; ARAP2; ADAP1; FAM13B; NF1; LRRK2; TBC1D10B; RASAL1; ARHGAP31; RAP1GAP2B
    opioid peptide activity ZFP106; PNOC; CDC42EP2; PENK; PDYN
    protein binding S1PR2; L3MBTL2; ATG13; SEMA7A; OCLN; MZT1; ZNF599; PRPF6; RRAGB; ZNF274

    CDC42EP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC42EP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC42EP2.

    CDC42; ARHGAP26; NME7

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