• Official Full Name
  • ELOVL fatty acid elongase 4
  • Background
  • This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration.
  • Synonyms
  • ELOVL4; ELOVL fatty acid elongase 4; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast) like 4 , STGD2, STGD3; elongation of very long chain fatty acids protein 4; cancer/testis antigen 118; CT118; 3-keto acyl-CoA synthase ELOVL4; ADMD; Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 4; elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast)-like 4; Elongation of very long chain fatty acids like 4; ELOV L4; ELOV4_HUMAN; ELOVL 4; FLJ17667; FLJ92876; Stargardt disease 3; Stargardt disease 3 autosomal dominant; STGD 2; STGD 3; STGD2; STGD3; Stargardt disease 3 (autosomal dominant); elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ELOVL4 Protein, GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ELOVL4 Protein
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus ELOVL4 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ELOVL4 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ELOVL4

Involved Pathway

ELOVL4 involved in several pathways and played different roles in them. We selected most pathways ELOVL4 participated on our site, such as Fatty acid elongation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELOVL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Fatty acid elongation

Protein Function

ELOVL4 has several biochemical functions, for example, transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ELOVL4 itself. We selected most functions ELOVL4 had, and list some proteins which have the same functions with ELOVL4. You can find most of the proteins on our site.
Related Protein
Function transferase activity
Related Protein AANAT; CD38; NLK2; FUT9A; STK30; MAPK12B; ELOVL7; GYG1A; CCDC111; MGAT4C

ELOVL4 Related Articles

Agbaga, MP; Tam, BM; et al. Mutant ELOVL4 That Causes Autosomal Dominant Stargardt-3 Macular Dystrophy Is Misrouted to Rod Outer Segment Disks. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:3669-3680(2014).
Kuny, S; Gaillard, F; et al. Inner Retina Remodeling in a Mouse Model of Stargardt-like Macular Dystrophy (STGD3). INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 51:2248-2262(2010).