|Official Full Name||G protein-coupled receptor 50|
|Background||This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women.|
|Synonyms||GPR50; G protein-coupled receptor 50; melatonin-related receptor; H9; Mel1c; G protein coupled receptor 50; GPR 50; MGC125342; MTNRL|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GPR50 involved in several pathways and played different roles in them. We selected most pathways GPR50 participated on our site, such as GPCRs, Class A Rhodopsin-like, Neuroactive ligand-receptor interaction, Small Ligand GPCRs, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|GPCRs, Class A Rhodopsin-like||AGTR2; FPR-RS4; CCR1; OPN3; HRH3; CCR7; GPR65; CMKLR1; SSTR4; GPR1|
|Neuroactive ligand-receptor interaction||LEPB; SSTR4; GRM2A; GABRA6; HTR1B; TAAR7F; GRIK2; GRM4; TSHB; GRM6B|
|Small Ligand GPCRs||GPR50|
GPR50 has several biochemical functions, for example, G-protein coupled receptor activity, identical protein binding, melatonin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR50 itself. We selected most functions GPR50 had, and list some proteins which have the same functions with GPR50. You can find most of the proteins on our site.
|G-protein coupled receptor activity||GPR31; OR7D2; GNRHR3; CALCRL; GPR75; GPR158; TAAR14F; GHSR; TAS1R2.1; NPFFR1L3|
|identical protein binding||TPRG1L; FHIT; TRIM8; TP53; HAPLN2; SLK; DDX58; RAD52; CDC42BPA; ACADM|
|melatonin receptor activity||MTNR1A; MTNR1BA; MTNR1AL; MTNR1B; MTNR1AA; GPR50; MTNR1BB; MTNR1C|
|protein binding||KCNS2; TLE2; MED15; AARSD1; TGFBR3; METAP2; CDKN2D; PBX2; JUP; SOCS7|
GPR50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR50 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR50.
MT1A; ZNF572; MT2A; GNAI1