GPR50 Protein, G protein-coupled receptor 50

GPR50

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GPR50

Official Full Name G protein-coupled receptor 50
Background This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women.
Synonyms GPR50; G protein-coupled receptor 50; melatonin-related receptor; H9; Mel1c; G protein coupled receptor 50; GPR 50; MGC125342; MTNRL
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GPR50-13478H Recombinant Human GPR50, GST-tagged E.coli GST
    Human GPR50-5249H Recombinant Human GPR50 Protein Wheat Germ N/A
    Human GPR50-5250H Recombinant Human GPR50 Protein, GST-tagged Wheat Germ GST
    Human GPR50-746HCL Recombinant Human GPR50 cell lysate N/A
    Mouse GPR50-7191M Recombinant Mouse GPR50 Protein Mammalian Cell His
    Chicken GPR50-6913C Recombinant Chicken GPR50 Mammalian Cell His
    Kit-1318 GPR50 CHO-K1 β-Arrestin Orphan GPCR Assay Kit N/A

    GPR50 involved in several pathways and played different roles in them. We selected most pathways GPR50 participated on our site, such as GPCRs, Class A Rhodopsin-like, Neuroactive ligand-receptor interaction, Small Ligand GPCRs, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    GPCRs, Class A Rhodopsin-like AGTR2; FPR-RS4; CCR1; OPN3; HRH3; CCR7; GPR65; CMKLR1; SSTR4; GPR1
    Neuroactive ligand-receptor interaction LEPB; SSTR4; GRM2A; GABRA6; HTR1B; TAAR7F; GRIK2; GRM4; TSHB; GRM6B
    Small Ligand GPCRs GPR50

    GPR50 has several biochemical functions, for example, G-protein coupled receptor activity, identical protein binding, melatonin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR50 itself. We selected most functions GPR50 had, and list some proteins which have the same functions with GPR50. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity GPR31; OR7D2; GNRHR3; CALCRL; GPR75; GPR158; TAAR14F; GHSR; TAS1R2.1; NPFFR1L3
    identical protein binding TPRG1L; FHIT; TRIM8; TP53; HAPLN2; SLK; DDX58; RAD52; CDC42BPA; ACADM
    melatonin receptor activity MTNR1A; MTNR1BA; MTNR1AL; MTNR1B; MTNR1AA; GPR50; MTNR1BB; MTNR1C
    protein binding KCNS2; TLE2; MED15; AARSD1; TGFBR3; METAP2; CDKN2D; PBX2; JUP; SOCS7

    GPR50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR50 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR50.

    MT1A; ZNF572; MT2A; GNAI1

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