Recombinant Full Length Human GPR50 Protein, GST-tagged

• Cat.No.: GPR50-5597HF
• Product Overview: Human GPR50 full-length ORF ( AAI03697.1, 1 a.a. - 617 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 93.8 kDa
• Protein Length: 617 amino acids
• AA Sequence: MGPTLAVPTPYGCIGCKLPQPEYPP ALIIFMFCAMVITIVVDLIGNSMVI LAVTKNKKLRNSGNIFVVSLSVADM LVAIYPYPLMLHAMSIGGWDLSQLQ CQMVGFITGLSVVGSIFNIVAIAIN RYCYICHSLQYERIFSVRNTCIYLV ITWIMTVLAVLPNMYIGTIEYDPRT YTCIFNYLNNPVFTVTIVCIHFVLP LLIVGFCYVRIWTKVLAARDPAGQN PDNQLAEVRNFLTMFVIFLLFAVCW CPINVLTVLVAVSPKEMAGKIPNWL YLAAYFIAYFNSCLNAVIYGLLNEN FRREYWTIFHAMRHPIIFFSGLISD IREMQEARTLARARAHARDQAREQD RAHACPAVEETPMNVRNVPLPGDAA AGHPDRASGHPKPHSRSSSAYRKSA STHHKSVFSHSKAASGHLKPVSGHS KPASGHPKSATVYPKPASVHFKADS VHFKGDSVHFKPDSVHFKPASSNPK PITGHHVSAGSHSKSAFSAATSHPK PTTGHIKPATSHAEPTTADYPKPAT TSHPKPTAADNPELSASHCPEIPAI AHPVSDDSDLPESASSPAAGPTKPA ASQLESDTIADLPDPTVVTTSTNDY HDVVVVDVEDDPDEMAV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GPR50 G protein-coupled receptor 50 [ Homo sapiens ]
• Official Symbol: GPR50
• Synonyms: GPR50; G protein-coupled receptor 50; melatonin-related receptor; H9; Mel1c; MGC125342
• Gene ID: 9248
• mRNA Refseq: NM_004224
• Protein Refseq: NP_004215
• MIM: 300207
• UniProt ID: Q13585