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HADH

  • Official Full Name

    hydroxyacyl-CoA dehydrogenase

  • Overview

    This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15.
  • Synonyms

    HADH; hydroxyacyl-CoA dehydrogenase; HADHSC, hydroxyacyl Coenzyme A dehydrogenase , L 3 hydroxyacyl Coenzyme A dehydrogenase, short chain; hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; HADH1; SCHAD; short-chain 3-hydroxyacyl-CoA dehydrogenase; L-;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • SUMO
  • Myc
  • DDK
  • MYC
  • N/A
  • N
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HADH-845H Recombinant Human Hydroxyacyl-CoA Dehydrogenase, T7-tagged E.coli T7
Human HADH-4557H Recombinant Human HADH Protein, GST-tagged Wheat Germ GST
Human HADH-1694H Recombinant Human Hydroxyacyl-Coenzyme A Dehydrogenase, His-tagged Human His
Human HADH-27760TH Recombinant Human HADH N/A
Human HADH-2032H Recombinant Human HADH, His-tagged E.coli His
Human HADH-5646HCL Recombinant Human HADH 293 Cell Lysate HEK293 N/A
Human HADH-3446HF Recombinant Full Length Human HADH Protein, GST-tagged In Vitro Cell Free System GST 314 amino acids
Human HADH-1041H Recombinant Human HADH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HADH-1041H-B Recombinant Human HADH Protein Pre-coupled Magnetic Beads HEK293
Human HADH-6604H Recombinant Human HADH Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HADH-933HFL Recombinant Full Length Human HADH Protein, C-Flag-tagged Mammalian cells Flag
Human HADH-2866H Recombinant Human HADH Protein (Met1-Arg236), N-His tagged E.coli N-His Met1-Arg236
Mouse Hadh-8167M Recombinant Mouse Hadh protein, His & T7-tagged E.coli His/T7 Met1~Ala167 (Accession # Q61425)
Mouse HADH-7468M Recombinant Mouse HADH Protein Mammalian Cell His
Mouse Hadh-1092M Recombinant Mouse Hadh Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Hadh-4507M Recombinant Mouse Hadh protein, His-SUMO-tagged E.coli His-SUMO 13-314aa
Mouse HADH-4051M Recombinant Mouse HADH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HADH-4051M-B Recombinant Mouse HADH Protein Pre-coupled Magnetic Beads HEK293
Rat HADH-2781R Recombinant Rat HADH Protein Mammalian Cell His
Rat HADH-2435R Recombinant Rat HADH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Hadh-1613R Recombinant Rat Hadh Protein, His-tagged E.coli N-His Met1-Ala167
Rat HADH-2435R-B Recombinant Rat HADH Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HADH-2032R Recombinant Rhesus monkey HADH Protein, His-tagged Mammalian Cell His
Rhesus Macaque HADH-1853R Recombinant Rhesus Macaque HADH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HADH-1853R-B Recombinant Rhesus Macaque HADH Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HADH-956Z Recombinant Zebrafish HADH Mammalian Cell His
Chicken HADH-5234C Recombinant Chicken HADH Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HADH involved in several pathways and played different roles in them. We selected most pathways HADH participated on our site, such as Fatty acid elongation, Fatty acid degradation, Valine, leucine and isoleucine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HADH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Fatty acid elongationELOVL3;PTPLA;ELOVL7A;ELOVL7;HADHAA;PTPLAD2;TECR;ELOVL2;HADH
Fatty acid degradationACOX1;ACAA1;ACADM;ECI2;EHHADH;HADHB;CPT1A;ACAA2;ACSL1B
Valine, leucine and isoleucine degradationMCCC1;HADHB;HMGCS2;IL4I1;HADHA;MCCC2;ALDH2.1;BCAT2;ALDH9A1
Lysine degradationACAT2;SETD1BA;HADHAB;ALDH1B1;ACAT1;SETMAR;ALDH9A1B;SETD8;OGDHA
Tryptophan metabolismAADAT;MAOB;ALDH9A1;AOX3L1;TPH1A;TPH1B;IL4I1;AANAT1;DHCR24
Butanoate metabolismABAT;ECHS1;HMGCS1;GAD1B;ACSM2;OXCT2B;HMGCS2;ACSM4;ACSM3
Metabolic pathwaysST6GALNAC3;ALG3;GUK1B;ALDH2.1;SPHK1;ENO1A;GGT5;OGDHL;IL4I1
Fatty acid metabolismACSL4;ELOVL6;ACAA1A;ELOVL5;ACAA1;HADHAA;FADS2;CPT1A;ACSL4B

HADH has several biochemical functions, for example, 3-hydroxyacyl-CoA dehydrogenase activity, NAD+ binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HADH itself. We selected most functions HADH had, and list some proteins which have the same functions with HADH. You can find most of the proteins on our site.

Function Related Protein
3-hydroxyacyl-CoA dehydrogenase activityHADHAB;HADH;HADHAA;HSD17B8;HADHB;EHHADH;HADHA;HSD17B4;H2-KE6
NAD+ bindingHPGD;SIRT2;SIRT3;SIRT7;SIRT6;UXS1;ALDH1A3;SIRT4;GLUD1

HADH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HADH here. Most of them are supplied by our site. Hope this information will be useful for your research of HADH.

UBA5; ADH1A; STAT1; 2_aha_camp; 8-aha-camp; 8-aha-omethyladenosine

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