Recombinant Full Length Human HADH Protein, C-Flag-tagged

• Cat.No.: HADH-933HFL
• Product Overview: Recombinant Full Length Human HADH Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 32.8 kDa
• AA Sequence: MAFVTRQFMRSVSSSSTASASAKKI IVKHVTVIGGGLMGAGIAQVAAATG HTVVLVDQTEDILAKSKKGI EESLRKVAKKKFAENPKAGDEFVEK TLSTIATSTDAASVVHSTDLVVEAI VENLKVKNELFKRLDKFAAE HTIFASNTSSLQITSIANATTRQDR FAGLHFFNPVPVMKLVEVIKTPMTS QKTFESLVDFSKALGKHPVS CKDTPGFIVNRLLVPYLMEAIRLYE RGDASKEDIDTAMKLGAGYPMGPFE LLDYVGLDTTKFIVDGWHEM
  DAENPLHQPSPSLNKLVAENKFGKK TGEGFYKYKTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Pathways: Butanoate metabolism, Fatty acid elongation in mitochondria, Fatty acid metabolism, Lysine degradation, Metabolic pathways, Tryptophan metabolism, Valine, leucine and isoleucine degradation

Gene Information

• Gene Name: HADH hydroxyacyl-CoA dehydrogenase [ Homo sapiens (human) ]
• Official Symbol: HADH
• Synonyms: HAD; HCDH; HHF4; HADH1; SCHAD; HADHSC; MSCHAD
• Gene ID: 3033
• mRNA Refseq: NM_005327.7
• Protein Refseq: NP_005318.6
• MIM: 601609
• UniProt ID: Q16836