MYOD1 Protein, myogenic differentiation 1


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Official Full Name myogenic differentiation 1
Background MyoD is a protein with a key role in regulating muscle differentiation. MyoD belongs to a family of proteins known as myogenic regulatory factors (MRFs). These bHLH (basic helix loop helix) transcription factors act sequentially in myogenic differentiation. MRF family members include MyoD, Myf5, myogenin, and MRF4 (Myf6).
Synonyms MyoD; MYOD1; MYF3; MYOD; PUM; bHLHc1; myogenic differentiation 1; myoblast determination protein 1; myf-3; myogenic factor 3; class C basic helix-loop-helix protein 1
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Arg
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MYOD1-143H Recombinant Human MYOD1 protein, Arginine-tagged E.coli Arg
    Human MYOD1-163H Recombinant Human Myogenic Differentiation 1 E.coli N/A
    Human MYOD1-165H Recombinant Human MYOD1, His-tagged E.coli His
    Human MYOD1-166H Recombinant Human MYOD1, GST-tagged E.coli GST
    Human MYOD1-167H Recombinant Human MYOD1, GST-tagged E.coli GST
    Human MYOD1-287H Recombinant Human MYOD1 Mammalian Cell His
    Human MYOD1-4005HCL Recombinant Human MYOD1 293 Cell Lysate HEK293 N/A
    Human MYOD1-5851H Recombinant Human MYOD1 Protein, GST-tagged Wheat Germ GST
    Mouse MYOD1-10349M Recombinant Mouse MYOD1 Protein Mammalian Cell His
    Rat MYOD1-3871R Recombinant Rat MYOD1 Protein Mammalian Cell His
    Chicken MYOD1-5788C Recombinant Chicken MYOD1 Mammalian Cell His
    Zebrafish MYOD1-8857Z Recombinant Zebrafish MYOD1 Mammalian Cell His

    MYOD1 involved in several pathways and played different roles in them. We selected most pathways MYOD1 participated on our site, such as C-MYB transcription factor network, CDO in myogenesis, Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYOD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    C-MYB transcription factor network CEBPA; YEATS4; ADA; CEBPB; ADORA2B; PTCRA; CSF1R; SMARCA2; COL1A2; TRIM28
    CDO in myogenesis CDON; CTNNA2; MEF2AA; MYF6; CTNNA1; TCF3A; CDH4; MEF2B; MYOD1; TCF3B
    Developmental Biology MED29; DNM2; CLASP1; TRPC3; NR6A1; SCN3A; CNTN6; NTN1A; AP2M1; RGMA
    Id Signaling Pathway TCF12; MSC; ELK3; MYOD1; TCF3B; MYOG; IFI16; PAX2; MYF6; ACVRL1
    Myogenesis TCF12; TCF4; MYOG; SPAG9; MYF6; BOC; MYOD1; TCF3B; CDH4; CDON
    Notch-mediated HES/HEY network GATA1; CTBP1; MYOD1; ASCL1; TLE1; HEY1; HES6; MYB; BGLAP; YY1
    Regulation of nuclear SMAD2/3 signaling SNIP1; NKX2; CITED1; FOXH1; GSC; SKI; CBFB; MYOD1
    Regulation of retinoblastoma protein CKM; SMARCB1; CBX4; AATF; GSC; BGLAP; BRD2; ELF1; MYOD1; ATF7

    MYOD1 has several biochemical functions, for example, E-box binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MYOD1 itself. We selected most functions MYOD1 had, and list some proteins which have the same functions with MYOD1. You can find most of the proteins on our site.

    Function Related Protein
    E-box binding TWIST1; C1orf51; NEUROG1; ARNTL2; ARNTL; NEUROD1; PER1; BHLHE40; LMO2; TCF21
    RNA polymerase II core promoter proximal region sequence-specific DNA binding KLF17; PGR; AKNA; ESRRA; TFAP2E; SMAD3; SIX1; ETV1; TFAP2A; CHD7
    RNA polymerase II regulatory region sequence-specific DNA binding SUV39H1; BARX2; PLAGL1; HES6; SATB1; ZNF549; ZNF792; ZFY1; GATA1; NME2
    chromatin DNA binding GRHL2; NOTCH1; MED1; HIST1H1E; SMAD3; RUVBL2; ATOH1; HIST1H1B; VAX1; H2AFY
    core promoter binding PYDC3; GTF2B; MYBBP1A; RELB; HDAC2; CRY1; HDAC6; SAFB; EZH2; NEUROG3
    nuclear hormone receptor binding NRIP1; MED1; HIF1A; NCOA2; ACTN4; NCOA1; CRY1; NCOR1; CTNNB1; TCF7L2
    protein binding MARCH10; ERCC2; CD97; NR2F6; ADRA2C; CSRP2; LRPAP1; RAB3IP; LCP2; MAP2K7
    protein heterodimerization activity SLC51B; SUPT5H; AGTR1; SEPHS1; RELA; SMC3; ADRA2A; UGT1A4; PRSS28; HIF1A
    transcription coactivator activity BRD7; NR5A1; VGLL2; NFKBIB; UTF1; ENY2; SETD3; ZSCAN1; DDX17; DDX5
    transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding SOX17; IRF8; TEAD2; POU4F1; TFAP4; GLI1; MEF2C; RFX1; GATA4; NKX2-5
    transcription factor binding KEAP1; HMGB2; REST; PURB; HDAC11; JUNB; EGR1; JUN; MED25; PPP1R13BA
    transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding SOHLH2; AIRE; OSR2; BARX1; NR1I2; CTCF; REST; CREB3L4; MYOD1; CSRNP3
    ubiquitin protein ligase binding CUL3A; TANK; RNF20; FZD8; Fzd4; CHEK2; SMAD7; BID; TNFRSF14; RIPK1

    MYOD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYOD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYOD1.


    Yaden, BC; Wang, YX; et al. Inhibition of Activin A Ameliorates Skeletal Muscle Injury and Rescues Contractile Properties by Inducing Efficient Remodeling in Female Mice. AMERICAN JOURNAL OF PATHOLOGY 184:1152-1166(2014).
    Czykier, E; Bielecki, W; et al. Case of chronic progressive epididymitis in a European bison. MEDYCYNA WETERYNARYJNA 68:299-302(2012).

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