myod1
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  • Official Full Name
  • myogenic differentiation 1
  • Background
  • MyoD is a protein with a key role in regulating muscle differentiation. MyoD belongs to a family of proteins known as myogenic regulatory factors (MRFs). These bHLH (basic helix loop helix) transcription factors act sequentially in myogenic differentiation. MRF family members include MyoD, Myf5, myogenin, and MRF4 (Myf6).
  • Synonyms
  • MyoD; MYOD1; MYF3; MYOD; PUM; bHLHc1; myogenic differentiation 1; myoblast determination protein 1; myf-3; myogenic factor 3; class C basic helix-loop-helix protein 1
Cat.#:MYOD1-5851HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MYOD1 Protein, GST-tagged
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Cat.#:MYOD1-143HTag:Arg
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MYOD1 protein, Arginine-tagged
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Cat.#:MYOD1-163HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Myogenic Differentiation 1
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Cat.#:MYOD1-165HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MYOD1, His-tagged
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Cat.#:MYOD1-166HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MYOD1, GST-tagged
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Cat.#:MYOD1-167HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MYOD1, GST-tagged
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Cat.#:MYOD1-287HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human MYOD1
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Cat.#:MYOD1-10349MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MYOD1 Protein
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Cat.#:MYOD1-3871RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MYOD1 Protein
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Cat.#:MYOD1-5788CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MYOD1
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Cat.#:MYOD1-8857ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MYOD1
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Cat.#:MYOD1-4005HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MYOD1 293 Cell Lysate
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Involved Pathway

MYOD1 involved in several pathways and played different roles in them. We selected most pathways MYOD1 participated on our site, such as C-MYB transcription factor network, CDO in myogenesis, Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYOD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
C-MYB transcription factor network
LECT2; SKI; CDK6; CREBBP; CBX4; ADORA2B; MYB; PIAS3; TRIM28; ELANE
CDO in myogenesis
MYOG; MYF6; TCF3B; SPAG9; TCF12; CDH2; MYOD1; MEF2AA; BNIP2; CTNNA2
Developmental Biology
EPHA10; RASGRP4; EFNB1; CDON; NR6A1; INSM1A; SPRED3; PRDM14; RND1L; SEMA3AA
Id Signaling Pathway
MYOD1; ACVRL1; KDR; TCF12; IFI16; TCF3B; MYF6; PAX2; MYOG; ELK3
Myogenesis
BNIP2; MYF6; TCF3B; MEF2AA; TCF3A; TCF4; CDON; MEF2B; MYOG; BOC
Notch-mediated HES/HEY network
BGLAP; HES6; CTBP1; TLE1; MYOD1; GATA1; GATA6; MYB; YY1; RCAN1
Regulation of nuclear SMAD2/3 signaling
CBFB; SKI; NKX2; GSC; MYOD1; FOXH1; CITED1; SNIP1
Regulation of retinoblastoma protein
AATF; ATF7; SMARCB1; BGLAP; MYOD1; ELF1; CBX4; GSC; BRD2; CKM

Protein Function

MYOD1 has several biochemical functions, for example, E-box binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MYOD1 itself. We selected most functions MYOD1 had, and list some proteins which have the same functions with MYOD1. You can find most of the proteins on our site.
Function
Related Protein
Function E-box binding
Related Protein C1orf51; ASCL2; ATOH8; GATA3; BHLHE40; TCF21; MYOD1; TWIST1; ZEB1; AHR
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein SOX1; EBF2; CARF; LEF1; E2F8; ZNF395; ZSCAN21; SFPI1; MYF6; RBPJ
Function RNA polymerase II regulatory region sequence-specific DNA binding
Related Protein POU3F4; PHF21A; RELB; ZNF583; FOXF1; RARG; ZNF792; BARX1; PHOX2A; HES6
Function chromatin DNA binding
Related Protein BCL6; ATOH1; INSM1A; INSM1B; WBP2; EZH2; RXRA; PPARGC1A; MYOD1; SLAMF7
Function core promoter binding
Related Protein MTA1; MTF1; XBP1; INSM1A; NKX3; PSPC1; DHX36; RBMX; GATA1; CCAR1
Function nuclear hormone receptor binding
Related Protein NCOA1; CTNNB1; CRY1; EP300; SNW1; TACC2; Ankar; HIF1A; NCOA2; SMARCD3
Function protein binding
Related Protein CACNG2; FCN1; FRK; CAMK1; AKR1C1; C12orf49; HIF1AN; RAB13; LGR4; ITGB4
Function protein heterodimerization activity
Related Protein USF1; CUL3; NKX2; HIST1H2BA; OSTB; HIST1H4B; TCF3A; SOX32; NEFL; THRA
Function transcription coactivator activity
Related Protein SOX10; RARA; SERTAD2; MED13; PPARGC1A; TRIM24; TFDP1B; TDRD3; MED23; NEUROG3
Function transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Related Protein HNF4A; CREB1; MEIS1; ATF2; NFIX; BHLHE40; SPI1; PKNOX1; SNAI2; POU4F1
Function transcription factor binding
Related Protein CEBPG; RBL1; CEBPA; DRG1; PIK3R1; PSMD4; BCL10; THRA; HEY2; HMGA2
Function transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
Related Protein GATA6; GATA1; PAX9; NR1I2; GRHL3; DLX2; CSRNP3; BARHL2; SOHLH1; CREB3L3
Function ubiquitin protein ligase binding
Related Protein UBE2G1A; GSK3B; UBE2KA; JKAMP; SMAD3; RFFL; NPLOC4; TRAF2; TMBIM6; UBE2V2

Interacting Protein

MYOD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYOD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYOD1.
SRF; TCF3; SIRT2; CSRP3; KPNA3; SMAD7; POLR2G; SMAD4; C2orf88; PSME2; KAT2B

MYOD1 Related Articles

Yaden, BC; Wang, YX; et al. Inhibition of Activin A Ameliorates Skeletal Muscle Injury and Rescues Contractile Properties by Inducing Efficient Remodeling in Female Mice. AMERICAN JOURNAL OF PATHOLOGY 184:1152-1166(2014).
Czykier, E; Bielecki, W; et al. Case of chronic progressive epididymitis in a European bison. MEDYCYNA WETERYNARYJNA 68:299-302(2012).