• Official Full Name
  • NGFI-A binding protein 2 (EGR1 binding protein 2)
  • Background
  • This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
  • Synonyms
  • NAB2; NGFI-A binding protein 2 (EGR1 binding protein 2); NGFI-A-binding protein 2; MADER; EGR1 binding protein 2; EGR-1-binding protein 2; melanoma-associated delayed early response protein; MGC75085
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human NAB2
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey NAB2 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NAB2
Source (Host):Species:Human
Product nameRecombinant Human NAB2 293 Cell Lysate

Protein Function

NAB2 has several biochemical functions, for example, protein binding, transcription corepressor activity, transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NAB2 itself. We selected most functions NAB2 had, and list some proteins which have the same functions with NAB2. You can find most of the proteins on our site.
Related Protein
Function protein binding
Function transcription corepressor activity
Related Protein SRSF2; SIRT1; SNW1; NR2F2; C1QBP; BATF3; PRMT5; WWTR1; ZHX2; DAXX
Function transcription factor binding
Related Protein VDRA; ERCC3; HES2; HEY1; DOT1L; ZBTB49; TP73; HES7; FOXC1; ZEB1

Interacting Protein

NAB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NAB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NAB2.
NEDD9; ZMYND19; a8kad6_human; 80125; g2xkq0_human

NAB2 Related Articles

Vogels, RJC; Vlenterie, M; et al. Solitary fibrous tumor - clinicopathologic, immunohistochemical and molecular analysis of 28 cases. DIAGNOSTIC PATHOLOGY 9:-(2014).
Cheah, AL; Billings, SD; et al. STAT6 rabbit monoclonal antibody is a robust diagnostic tool for the distinction of solitary fibrous tumour from its mimics. PATHOLOGY 46:389-395(2014).