| Description : |
This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
56.6 kDa |
| AA Sequence : |
MHRAPSPTAEQPPGGGDSARRTLQP RLKPSARAMALPRTLGELQLYRVLQ RANLLSYYETFIQQGGDDVQQLCEA GEEEFLEIMALVGMATKPLHVRRLQ KALREWATNPGLFSQPVPAVPVSSI PLFKISETAGTRKGSMSNGHGSPGE KAGSARSFSPKSPLELGEKLSPLPG GPGAGDPRIWPGRSTPESDVGAGGE EEAGSPPFSPPAGGGVPEGTGAGGL AAGGTGGGPDRLEPEMVRMVVESVE RIFRSFPRGDAGEVTSLLKLNKKLA RSVGHIFEMDDNDSQKEEEIRKYSI IYGRFDSKRREGKQLSLHELTINEA AAQFCMRDNTLLLRRVELFSLSRQV ARESTYLSSLKGSRLHPEELGGPPL KKLKQEVGEQSHPEIQQPPPGPESY VPPYRPSLEEDSASLSGESLDGHLQ AVGSCPRLTPPPADLPLALPAHGLW SRHILQQTLMDEGLRLARLVSHDRV GRLSPCVPAKPPLAEFEEGLLDRCP APGPHPALVEGRRSSVKVEAEASRQ TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
